AHSA2
| AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) | |||||||
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| Identifiers | |||||||
| Symbol | AHSA2 | ||||||
| Alt. symbols | Hch1 | ||||||
| NCBI gene | 130872 | ||||||
| HGNC | 20437 | ||||||
| RefSeq | NM_152392 | ||||||
| UniProt | Q719I0 | ||||||
| Other data | |||||||
| Locus | Chr. 2 p14 | ||||||
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AHSA2 also known as AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) is a human gene which encodes a protein which acts as co-chaperone of Hsp90 (heat shock protein 90).[1] AHSA2 and the related AHSA1 belongs to the AHA (Activator of Hsp90 ATPase) family of stress-regulated proteins that bind directly to Hsp90 and are required for Hsp90-dependent activation of client proteins.[1]
References
[edit]- ^ a b Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C (December 2002). "Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1" (PDF). Mol. Cell. 10 (6): 1307–18. doi:10.1016/S1097-2765(02)00785-2. PMID 12504007.
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