Acidic leucine-rich nuclear phosphoprotein 32 family member D is a protein that in humans is encoded by the ANP32Dgene.[3][4][5]
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns.[5]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kadkol SS, Brody JR, Pevsner J, Bai J, Pasternack GR (Apr 1999). "Modulation of oncogenic potential by alternative gene use in human prostate cancer". Nat Med. 5 (3): 275–9. doi:10.1038/6488. PMID10086381. S2CID24559649.
Kadkol SS, El Naga GA, Brody JR, et al. (2002). "Expression of pp32 gene family members in breast cancer". Breast Cancer Res. Treat. 68 (1): 65–73. doi:10.1023/A:1017919507109. PMID11678310. S2CID11915912.
