Adamalysin

Adamalysin
Identifiers
EC no.3.4.24.46
CAS no.74812-51-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
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Adamalysin (EC 3.4.24.46, Crotalus adamanteus metalloendopeptidase, proteinase I and II, Crotalus adamanteus venom proteinase II, adamalysin II) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Phe1-Val, His5-Leu, His10-Leu, Ala14-Leu, Leu15-Tyr, and Tyr16-Leu of insulin B chain

This enzyme is present in the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

See also

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References

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  1. ^ Kurecki T, Laskowski M, Kress LF (November 1978). "Purification and some properties of two proteinases from Crotalus adamanteus venom that inactivate human alpha 1-proteinase inhibitor". The Journal of Biological Chemistry. 253 (22): 8340–5. PMID 309470.
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