List of EC numbers (EC 1)

This list contains a list of EC numbers for the first group, EC 1, oxidoreductases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee.^[1] The database is developed and maintained by Andrew McDonald.^[2]

EC 1.1 Acting on the CH-OH group of donors

EC 1.1.1 With Nicotinamide adenine dinucleotide or NADP as acceptor

EC 1.1.1.1: alcohol dehydrogenase
EC 1.1.1.2: alcohol dehydrogenase (NADP⁺)
EC 1.1.1.3: homoserine dehydrogenase
EC 1.1.1.4: (R,R)-butanediol dehydrogenase
EC 1.1.1.5: acetoin dehydrogenase. Now EC 1.1.1.303, diacetyl reductase [(R)-acetoin forming] and EC 1.1.1.304, diacetyl reductase [(S)-acetoin forming]
EC 1.1.1.6: glycerol dehydrogenase
EC 1.1.1.7: propanediol-phosphate dehydrogenase
EC 1.1.1.8: glycerol-3-phosphate dehydrogenase (NAD⁺)
EC 1.1.1.9: D-xylulose reductase
EC 1.1.1.10: L-xylulose reductase
EC 1.1.1.11: D-arabinitol 4-dehydrogenase
EC 1.1.1.12: L-arabinitol 4-dehydrogenase
EC 1.1.1.13: L-arabinitol 2-dehydrogenase
EC 1.1.1.14: L-iditol 2-dehydrogenase
EC 1.1.1.15: D-iditol 2-dehydrogenase
EC 1.1.1.16: galactitol 2-dehydrogenase
EC 1.1.1.17: mannitol-1-phosphate 5-dehydrogenase
EC 1.1.1.18: inositol 2-dehydrogenase
EC 1.1.1.19: glucuronate reductase
EC 1.1.1.20: glucuronolactone reductase
EC 1.1.1.207: (-)-menthol dehydrogenase
EC 1.1.1.208: (+)-neomenthol dehydrogenase
EC 1.1.1.21: aldose reductase
EC 1.1.1.22: UDP-glucose 6-dehydrogenase
EC 1.1.1.222: (R)-4-hydroxyphenyllactate dehydrogenase
EC 1.1.1.23: histidinol dehydrogenase|
EC 1.1.1.24: quinate/shikimate dehydrogenase (NAD⁺)
EC 1.1.1.25: shikimate dehydrogenase (NADP⁺)
EC 1.1.1.26: glyoxylate reductase
EC 1.1.1.27: L-lactate dehydrogenase
EC 1.1.1.28: D-lactate dehydrogenase
EC 1.1.1.29: glycerate dehydrogenase
EC 1.1.1.30: 3-hydroxybutyrate dehydrogenase
EC 1.1.1.31: 3-hydroxyisobutyrate dehydrogenase
EC 1.1.1.32: mevaldate reductase
EC 1.1.1.33: mevaldate reductase (NADPH)
EC 1.1.1.34: hydroxymethylglutaryl-CoA reductase (NADPH)
EC 1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase
EC 1.1.1.36: acetoacetyl-CoA reductase
EC 1.1.1.37: malate dehydrogenase
EC 1.1.1.38: malate dehydrogenase (oxaloacetate-decarboxylating)
EC 1.1.1.39: malate dehydrogenase (decarboxylating)
EC 1.1.1.40: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP⁺)
EC 1.1.1.41: isocitrate dehydrogenase (NAD⁺)
EC 1.1.1.42: isocitrate dehydrogenase (NADP⁺)
EC 1.1.1.43: phosphogluconate 2-dehydrogenase
EC 1.1.1.44: phosphogluconate dehydrogenase (NADP⁺-dependent, decarboxylating)
EC 1.1.1.45: L-gulonate 3-dehydrogenase
EC 1.1.1.46: L-arabinose 1-dehydrogenase
EC 1.1.1.47: glucose 1-dehydrogenase [NAD(P)⁺)]
EC 1.1.1.48: D-galactose 1-dehydrogenase
EC 1.1.1.49: glucose-6-phosphate dehydrogenase (NADP⁺)
EC 1.1.1.50: 3α-hydroxysteroid 3-dehydrogenase (Si-specific)
EC 1.1.1.51: 3(or 17)β-hydroxysteroid dehydrogenase
EC 1.1.1.52: 3α-hydroxycholanate dehydrogenase (NAD⁺)
EC 1.1.1.53: 3α(or 20β)-hydroxysteroid dehydrogenase
EC 1.1.1.54: allyl-alcohol dehydrogenase
EC 1.1.1.55: lactaldehyde reductase (NADPH)
EC 1.1.1.56: ribitol 2-dehydrogenase
EC 1.1.1.57: fructuronate reductase
EC 1.1.1.58: tagaturonate reductase
EC 1.1.1.59: 3-hydroxypropionate dehydrogenase
EC 1.1.1.60: 2-hydroxy-3-oxopropionate reductase
EC 1.1.1.61: 4-hydroxybutyrate dehydrogenase
EC 1.1.1.62: 17β-estradiol 17-dehydrogenase
EC 1.1.1.63: testosterone 17β-dehydrogenase. Now EC 1.1.1.239, 3α(17β)-hydroxysteroid dehydrogenase (NAD⁺)
EC 1.1.1.64: testosterone 17β-dehydrogenase (NADP⁺)
EC 1.1.1.65: pyridoxine 4-dehydrogenase
EC 1.1.1.66: ω-hydroxydecanoate dehydrogenase
EC 1.1.1.67: mannitol 2-dehydrogenase
EC 1.1.1.68: 5,10-methylenetetrahydrofolate reductase. Now EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.1.1.69: gluconate 5-dehydrogenase
EC 1.1.1.70: D-glucuronolactone dehydrogenase. Now included with EC 1.2.1.3 aldehyde dehydrogenase (NAD⁺)
EC 1.1.1.71: alcohol dehydrogenase [NAD(P)⁺]
EC 1.1.1.72: glycerol dehydrogenase (NADP⁺)
EC 1.1.1.73: octanol dehydrogenase
EC 1.1.1.74: D-aminopropanol dehydrogenase (reaction due to EC 1.1.1.4 (R,R)-butanediol dehydrogenase)
EC 1.1.1.75: (R)-aminopropanol dehydrogenase
EC 1.1.1.76: (S,S)-butanediol dehydrogenase
EC 1.1.1.77: lactaldehyde reductase
EC 1.1.1.78: methylglyoxal reductase (NADH-dependent)
EC 1.1.1.79: glyoxylate reductase (NADP⁺)
EC 1.1.1.80: isopropanol dehydrogenase (NADP⁺)
EC 1.1.1.81: hydroxypyruvate reductase
EC 1.1.1.82: malate dehydrogenase (NADP⁺)
EC 1.1.1.83: D-malate dehydrogenase (decarboxylating)
EC 1.1.1.84: dimethylmalate dehydrogenase
EC 1.1.1.85: 3-isopropylmalate dehydrogenase
EC 1.1.1.86: ketol-acid reductoisomerase (NADP⁺)
EC 1.1.1.87: homoisocitrate dehydrogenase
EC 1.1.1.88: hydroxymethylglutaryl-CoA reductase
EC 1.1.1.89: dihydroxyisovalerate dehydrogenase (isomerizing). Now included with EC 1.1.1.86 ketol-acid reductoisomerase
EC 1.1.1.90: aryl-alcohol dehydrogenase
EC 1.1.1.91: aryl-alcohol dehydrogenase (NADP⁺)
EC 1.1.1.92: oxaloglycolate reductase (decarboxylating)
EC 1.1.1.93: tartrate dehydrogenase
EC 1.1.1.94: glycerol-3-phosphate dehydrogenase [NAD(P)⁺]
EC 1.1.1.95: phosphoglycerate dehydrogenase
EC 1.1.1.96: diiodophenylpyruvate reductase
EC 1.1.1.97: 3-hydroxybenzyl-alcohol dehydrogenase
EC 1.1.1.98: (R)-2-hydroxy-fatty-acid dehydrogenase
EC 1.1.1.99: (S)-2-hydroxy-fatty-acid dehydrogenase
EC 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase
EC 1.1.1.101: acylglycerone-phosphate reductase
EC 1.1.1.102: 3-dehydrosphinganine reductase
EC 1.1.1.103: L-threonine 3-dehydrogenase
EC 1.1.1.104: 4-oxoproline reductase
EC 1.1.1.105: all-trans-retinol dehydrogenase (NAD⁺)
EC 1.1.1.106: pantoate 4-dehydrogenase
EC 1.1.1.107: pyridoxal 4-dehydrogenase
EC 1.1.1.108: carnitine 3-dehydrogenase
EC 1.1.1.109: Now EC 1.3.1.28, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
EC 1.1.1.110: aromatic 2-oxoacid reductase
EC 1.1.1.111: 3-(imidazol-5-yl)lactate dehydrogenase
EC 1.1.1.112: indanol dehydrogenase
EC 1.1.1.113: L-xylose 1-dehydrogenase
EC 1.1.1.114: apiose 1-reductase
EC 1.1.1.115: ribose 1-dehydrogenase (NADP⁺)
EC 1.1.1.116: D-arabinose 1-dehydrogenase (NAD⁺)
EC 1.1.1.117: D-arabinose 1-dehydrogenase [NAD(P)⁺]
EC 1.1.1.118: glucose 1-dehydrogenase (NAD⁺)
EC 1.1.1.119: glucose 1-dehydrogenase (NADP⁺)
EC 1.1.1.120: galactose 1-dehydrogenase (NADP⁺)
EC 1.1.1.121: aldose 1-dehydrogenase (NAD⁺)
EC 1.1.1.122: D-threo-aldose 1-dehydrogenase
EC 1.1.1.123: sorbose 5-dehydrogenase (NADP⁺)
EC 1.1.1.124: fructose 5-dehydrogenase (NADP⁺)
EC 1.1.1.125: 2-deoxy-D-gluconate 3-dehydrogenase
EC 1.1.1.126: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
EC 1.1.1.127: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
EC 1.1.1.128: The reaction described is covered by EC 1.1.1.264, L-idonate 5-dehydrogenase.
EC 1.1.1.129: L-threonate 3-dehydrogenase
EC 1.1.1.130: 3-dehydro-L-gulonate 2-dehydrogenase
EC 1.1.1.131: mannuronate reductase
EC 1.1.1.132: GDP-mannose 6-dehydrogenase
EC 1.1.1.133: dTDP-4-dehydrorhamnose reductase
EC 1.1.1.134: dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP⁺)
EC 1.1.1.135: GDP-6-deoxy-D-talose 4-dehydrogenase
EC 1.1.1.136: UDP-N-acetylglucosamine 6-dehydrogenase
EC 1.1.1.137: ribitol-5-phosphate 2-dehydrogenase
EC 1.1.1.138: mannitol 2-dehydrogenase (NADP⁺)
EC 1.1.1.139: polyol dehydrogenase (NADP⁺). Now included with EC 1.1.1.21 aldehyde reductase
EC 1.1.1.140: sorbitol-6-phosphate 2-dehydrogenase
EC 1.1.1.141: 15-hydroxyprostaglandin dehydrogenase (NAD⁺)
EC 1.1.1.142: D-pinitol dehydrogenase
EC 1.1.1.143: sequoyitol dehydrogenase
EC 1.1.1.144: perillyl-alcohol dehydrogenase
EC 1.1.1.145: 3β-hydroxy-Δ5-steroid dehydrogenase
EC 1.1.1.146: 11β-hydroxysteroid dehydrogenase
EC 1.1.1.147: 16α-hydroxysteroid dehydrogenase
EC 1.1.1.148: estradiol 17α-dehydrogenase
EC 1.1.1.149: 20α-hydroxysteroid dehydrogenase
EC 1.1.1.150: 21-hydroxysteroid dehydrogenase (NAD⁺)
EC 1.1.1.151: 21-hydroxysteroid dehydrogenase (NADP⁺)
EC 1.1.1.152: 3α-hydroxy-5β-androstane-17-one 3α-dehydrogenase
EC 1.1.1.153: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
EC 1.1.1.154: ureidoglycolate dehydrogenase
EC 1.1.1.155: homoisocitrate dehydrogenase. The enzyme is identical to EC 1.1.1.87, homoisocitrate dehydrogenase
EC 1.1.1.156: glycerol 2-dehydrogenase (NADP⁺)
EC 1.1.1.157: 3-hydroxybutyryl-CoA dehydrogenase
EC 1.1.1.158: Now EC 1.3.1.98, UDP-N-acetylmuramate dehydrogenase
EC 1.1.1.159: 7α-hydroxysteroid dehydrogenase
EC 1.1.1.160: dihydrobunolol dehydrogenase
EC 1.1.1.161: The activity is part of EC 1.14.13.15, cholestanetriol 26-monooxygenase
EC 1.1.1.162: erythrulose reductase
EC 1.1.1.163: cyclopentanol dehydrogenase
EC 1.1.1.164: hexadecanol dehydrogenase
EC 1.1.1.165: 2-alkyn-1-ol dehydrogenase
EC 1.1.1.166: hydroxycyclohexanecarboxylate dehydrogenase
EC 1.1.1.167: hydroxymalonate dehydrogenase
EC 1.1.1.168: 2-dehydropantolactone reductase (Re-specific)
EC 1.1.1.169: 2-dehydropantoate 2-reductase
EC 1.1.1.170: 3β-hydroxysteroid-4α-carboxylate 3-dehydrogenase (decarboxylating)
EC 1.1.1.171: Now EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.1.1.172: 2-oxoadipate reductase
EC 1.1.1.173: L-rhamnose 1-dehydrogenase
EC 1.1.1.174: cyclohexane-1,2-diol dehydrogenase
EC 1.1.1.175: D-xylose 1-dehydrogenase
EC 1.1.1.176: 12α-hydroxysteroid dehydrogenase
EC 1.1.1.177: glycerol-3-phosphate 1-dehydrogenase (NADP⁺)
EC 1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
EC 1.1.1.179: D-xylose 1-dehydrogenase (NADP⁺, D-xylono-1,5-lactone-forming)
EC 1.1.1.180: Now included with EC 1.1.1.131 mannuronate reductase
EC 1.1.1.181: cholest-5-ene-3β,7α-diol 3β-dehydrogenase
EC 1.1.1.182: Now included with EC 1.1.1.198 (+)-borneol dehydrogenase, EC 1.1.1.227 (-)-borneol dehydrogenase and EC 1.1.1.228 (+)-sabinol dehydrogenase
EC 1.1.1.183: geraniol dehydrogenase (NADP⁺)
EC 1.1.1.184: carbonyl reductase (NADPH)
EC 1.1.1.185: L-glycol dehydrogenase
EC 1.1.1.186: dTDP-galactose 6-dehydrogenase
EC 1.1.1.187: GDP-4-dehydro-D-rhamnose reductase
EC 1.1.1.188: prostaglandin-F synthase
EC 1.1.1.189: prostaglandin-E2 9-reductase
EC 1.1.1.190: indole-3-acetaldehyde reductase (NADH)
EC 1.1.1.191: indole-3-acetaldehyde reductase (NADPH)
EC 1.1.1.192: long-chain-alcohol dehydrogenase
EC 1.1.1.193: 5-amino-6-(5-phosphoribosylamino)uracil reductase
EC 1.1.1.194: coniferyl-alcohol dehydrogenase
EC 1.1.1.195: cinnamyl-alcohol dehydrogenase
EC 1.1.1.196: 15-hydroxyprostaglandin-D dehydrogenase (NADP⁺)
EC 1.1.1.197: 15-hydroxyprostaglandin dehydrogenase (NADP⁺)
EC 1.1.1.198: (+)-borneol dehydrogenase
EC 1.1.1.199: (S)-usnate reductase
EC 1.1.1.200: aldose-6-phosphate reductase (NADPH)
EC 1.1.1.228: (+)-sabinol dehydrogenase
EC 1.1.1.251: galactitol-1-phosphate 5-dehydrogenase
EC 1.1.1.252: tetrahydroxynaphthalene reductase
EC 1.1.1.253: Now EC 1.5.1.33, pteridine reductase
EC 1.1.1.254: (S)-carnitine 3-dehydrogenase
EC 1.1.1.255: mannitol dehydrogenase
EC 1.1.1.256: fluoren-9-ol dehydrogenase
EC 1.1.1.257: 4-(hydroxymethyl)benzenesulfonate dehydrogenase
EC 1.1.1.258: 6-hydroxyhexanoate dehydrogenase
EC 1.1.1.259: 3-hydroxypimeloyl-CoA dehydrogenase
EC 1.1.1.260: sulcatone reductase
EC 1.1.1.261: sn-glycerol-1-phosphate dehydrogenase
EC 1.1.1.262: 4-hydroxythreonine-4-phosphate dehydrogenase
EC 1.1.1.263: 1,5-anhydro-D-fructose reductase
EC 1.1.1.264: L-idonate 5-dehydrogenase
EC 1.1.1.265: 3-methylbutanal reductase
EC 1.1.1.266: dTDP-4-dehydro-6-deoxyglucose reductase
EC 1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase
EC 1.1.1.268: 2-(R)-hydroxypropyl-CoM dehydrogenase
EC 1.1.1.269: 2-(S)-hydroxypropyl-CoM dehydrogenase
EC 1.1.1.270: 3β-hydroxysteroid 3-dehydrogenase
EC 1.1.1.271: GDP-L-fucose synthase
EC 1.1.1.272: D-2-hydroxyacid dehydrogenase (NADP⁺)
EC 1.1.1.273: vellosimine dehydrogenase
EC 1.1.1.274: 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
EC 1.1.1.275: (+)-trans-carveol dehydrogenase
EC 1.1.1.276: serine 3-dehydrogenase (NADP⁺⁾
EC 1.1.1.277: 3β-hydroxy-5β-steroid dehydrogenase
EC 1.1.1.278: 3β-hydroxy-5α-steroid dehydrogenase
EC 1.1.1.279: (R)-3-hydroxyacid-ester dehydrogenase
EC 1.1.1.280: (S)-3-hydroxyacid-ester dehydrogenase
EC 1.1.1.281: GDP-4-dehydro-6-deoxy-D-mannose reductase
EC 1.1.1.282: quinate/shikimate dehydrogenase [NAD(P)⁺⁾]
EC 1.1.1.283: methylglyoxal reductase (NADPH-dependent)
EC 1.1.1.284: S-(hydroxymethyl)glutathione dehydrogenase
EC 1.1.1.285: 3′′-deamino-3′′-oxonicotianamine reductase
EC 1.1.1.286: isocitrate—homoisocitrate dehydrogenase
EC 1.1.1.287: D-arabinitol dehydrogenase (NADP⁺)
EC 1.1.1.288: xanthoxin dehydrogenase
EC 1.1.1.289: sorbose reductase
EC 1.1.1.290: 4-phosphoerythronate dehydrogenase
EC 1.1.1.291: 2-hydroxymethylglutarate dehydrogenase
EC 1.1.1.292: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
EC 1.1.1.293: tropinone reductase I. This enzyme was already in the Enzyme List as EC 1.1.1.206, tropine dehydrogenase so EC 1.1.1.293 has been withdrawn at the public-review stage
EC 1.1.1.294: chlorophyll(ide) b reductase
EC 1.1.1.295: momilactone-A synthase
EC 1.1.1.296: dihydrocarveol dehydrogenase
EC 1.1.1.297: limonene-1,2-diol dehydrogenase
EC 1.1.1.298: 3-hydroxypropionate dehydrogenase (NADP⁺)
EC 1.1.1.299: malate dehydrogenase [NAD(P)⁺⁾]
EC 1.1.1.300: NADP-retinol dehydrogenase
EC 1.1.1.301: D-arabitol-phosphate dehydrogenase
EC 1.1.1.302: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5′-phosphate reductase
EC 1.1.1.303: diacetyl reductase [(R)-acetoin forming]
EC 1.1.1.304: diacetyl reductase [(S)-acetoin forming]
EC 1.1.1.305: UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
EC 1.1.1.306: S-(hydroxymethyl)mycothiol dehydrogenase
EC 1.1.1.307: D-xylose reductase
EC 1.1.1.308: sulfopropanediol 3-dehydrogenase
EC 1.1.1.309: phosphonoacetaldehyde reductase (NADH)
EC 1.1.1.310: (S)-sulfolactate dehydrogenase
EC 1.1.1.311: (S)-1-phenylethanol dehydrogenase
EC 1.1.1.312: 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
EC 1.1.1.313: sulfoacetaldehyde reductase
EC 1.1.1.314: Now known to be catalyzed by EC 1.14.14.95, germacrene A hydroxylase
EC 1.1.1.315: 11-cis-retinol dehydrogenase
EC 1.1.1.316: L-galactose 1-dehydrogenase
EC 1.1.1.317: perakine reductase
EC 1.1.1.318: eugenol synthase
EC 1.1.1.319: isoeugenol synthase
EC 1.1.1.320: benzil reductase [(S)-benzoin forming]
EC 1.1.1.321: benzil reductase [(R)-benzoin forming]
EC 1.1.1.322: (–)-endo-fenchol dehydrogenase
EC 1.1.1.323: (+)-thujan-3-ol dehydrogenase
EC 1.1.1.324: 8-hydroxygeraniol dehydrogenase
EC 1.1.1.325: sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
EC 1.1.1.326: zerumbone synthase
EC 1.1.1.327: 5-exo-hydroxycamphor dehydrogenase
EC 1.1.1.328: nicotine blue oxidoreductase
EC 1.1.1.329: 2-deoxy-scyllo-inosamine dehydrogenase
EC 1.1.1.330: very-long-chain 3-oxoacyl-CoA reductase
EC 1.1.1.331: secoisolariciresinol dehydrogenase
EC 1.1.1.332: chanoclavine-I dehydrogenase
EC 1.1.1.333: decaprenylphospho-β-D-erythro-pentofuranosid-2-ulose 2-reductase
EC 1.1.1.334: methylecgonone reductase
EC 1.1.1.335: UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
EC 1.1.1.336: UDP-N-acetyl-D-mannosamine dehydrogenase
EC 1.1.1.337: L-2-hydroxycarboxylate dehydrogenase (NAD⁺)
EC 1.1.1.338: (2R)-3-sulfolactate dehydrogenase (NADP⁺)
EC 1.1.1.339: dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD⁺)
EC 1.1.1.340: 1-deoxy-11β-hydroxypentalenate dehydrogenase
EC 1.1.1.341: CDP-abequose synthase
EC 1.1.1.342: CDP-paratose synthase

At present (October 2021) most of the entries from 343 onwards have no Wikipedia articles

EC 1.1.1.343: phosphogluconate dehydrogenase (NAD⁺-dependent, decarboxylating)
EC 1.1.1.344: dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)⁺]
EC 1.1.1.345: D-2-hydroxyacid dehydrogenase (NAD⁺)
EC 1.1.1.346: 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
EC 1.1.1.347: geraniol dehydrogenase (NAD⁺)
EC 1.1.1.348: (3R)-2′-hydroxyisoflavanone reductase
EC 1.1.1.349: norsolorinic acid ketoreductase
EC 1.1.1.350: ureidoglycolate dehydrogenase (NAD⁺)
EC 1.1.1.351: phosphogluconate dehydrogenase [NAD(P)⁺-dependent, decarboxylating]
EC 1.1.1.352: 5′-hydroxyaverantin dehydrogenase
EC 1.1.1.353: versiconal hemiacetal acetate reductase
EC 1.1.1.354: farnesol dehydrogenase (NAD⁺)
EC 1.1.1.355: 2′-dehydrokanamycin reductase
EC 1.1.1.356: GDP-L-colitose synthase
EC 1.1.1.357: 3α-hydroxysteroid 3-dehydrogenase
EC 1.1.1.358: 2-dehydropantolactone reductase
EC 1.1.1.359: aldose 1-dehydrogenase [NAD(P)⁺]
EC 1.1.1.360: glucose/galactose 1-dehydrogenase
EC 1.1.1.361: glucose-6-phosphate 3-dehydrogenase
EC 1.1.1.362: aklaviketone reductase
EC 1.1.1.363: glucose-6-phosphate dehydrogenase [NAD(P)⁺]
EC 1.1.1.364: dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase
EC 1.1.1.365: D-galacturonate reductase
EC 1.1.1.366: L-idonate 5-dehydrogenase (NAD⁺)
EC 1.1.1.367: UDP-2-acetamido-2,6-β-L-arabino-hexul-4-ose reductase
EC 1.1.1.368: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
EC 1.1.1.369: D-chiro-inositol 1-dehydrogenase
EC 1.1.1.370: scyllo-inositol 2-dehydrogenase (NAD⁺)
EC 1.1.1.371: scyllo-inositol 2-dehydrogenase (NADP⁺)
EC 1.1.1.372: D/L-glyceraldehyde reductase
EC 1.1.1.373: sulfolactaldehyde 3-reductase
EC 1.1.1.374: UDP-N-acetylglucosamine 3-dehydrogenase
EC 1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)⁺]
EC 1.1.1.376: L-arabinose 1-dehydrogenase [NAD(P)⁺]
EC 1.1.1.377: L-rhamnose 1-dehydrogenase (NADP⁺)
EC 1.1.1.378: L-rhamnose 1-dehydrogenase [NAD(P)⁺]
EC 1.1.1.379: (R)-mandelate dehydrogenase
EC 1.1.1.380: L-gulonate 5-dehydrogenase
EC 1.1.1.381: 3-hydroxy acid dehydrogenase
EC 1.1.1.382: ketol-acid reductoisomerase (NAD⁺)
EC 1.1.1.383: ketol-acid reductoisomerase [NAD(P)⁺]
EC 1.1.1.384: dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase
EC 1.1.1.385: dihydroanticapsin dehydrogenase
EC 1.1.1.386: ipsdienol dehydrogenase
EC 1.1.1.387: L-serine 3-dehydrogenase (NAD⁺)
EC 1.1.1.388: glucose-6-phosphate dehydrogenase (NAD⁺)
EC 1.1.1.389: 2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase
EC 1.1.1.390: sulfoquinovose 1-dehydrogenase
EC 1.1.1.391: 3β-hydroxycholanate 3-dehydrogenase (NAD⁺)
EC 1.1.1.392: 3α-hydroxycholanate dehydrogenase (NADP⁺)
EC 1.1.1.393: 3β-hydroxycholanate 3-dehydrogenase (NADP⁺)
EC 1.1.1.394: aurachin B dehydrogenase
EC 1.1.1.395: 3α-hydroxy bile acid-CoA-ester 3-dehydrogenase
EC 1.1.1.396: bacteriochlorophyllide a dehydrogenase
EC 1.1.1.397: β-methylindole-3-pyruvate reductase
EC 1.1.1.398: 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase
EC 1.1.1.399: 2-oxoglutarate reductase
EC 1.1.1.400: 2-methyl-1,2-propanediol dehydrogenase
EC 1.1.1.401: 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD⁺)
EC 1.1.1.402: D-erythritol 1-phosphate dehydrogenase
EC 1.1.1.403: D-threitol dehydrogenase (NAD⁺)
EC 1.1.1.404: tetrachlorobenzoquinone reductase
EC 1.1.1.405: ribitol-5-phosphate 2-dehydrogenase (NADP⁺)
EC 1.1.1.406: galactitol 2-dehydrogenase (L-tagatose-forming)
EC 1.1.1.407: D-altritol 5-dehydrogenase
EC 1.1.1.408: 4-phospho-D-threonate 3-dehydrogenase
EC 1.1.1.409: 4-phospho-D-erythronate 3-dehydrogenase
EC 1.1.1.410: D-erythronate 2-dehydrogenase
EC 1.1.1.411: L-threonate 2-dehydrogenase
EC 1.1.1.412: 2-alkyl-3-oxoalkanoate reductase
EC 1.1.1.413: A-factor type γ-butyrolactone 1′-reductase (1S-forming)
EC 1.1.1.414: L-galactonate 5-dehydrogenase
EC 1.1.1.415: noscapine synthase
EC 1.1.1.416: isopyridoxal dehydrogenase (5-pyridoxolactone-forming)
EC 1.1.1.417: 3β-hydroxysteroid-4β-carboxylate 3-dehydrogenase (decarboxylating)
EC 1.1.1.418: plant 3β-hydroxysteroid-4α-carboxylate 3-dehydrogenase (decarboxylating)
EC 1.1.1.419: nepetalactol dehydrogenase
EC 1.1.1.420: D-apiose dehydrogenase
EC 1.1.1.421: D-apionate oxidoisomerase
EC 1.1.1.422: pseudoephedrine dehydrogenase
EC 1.1.1.423: (1R,2S)-ephedrine 1-dehydrogenase
EC 1.1.1.424: D-xylose 1-dehydrogenase (NADP⁺, D-xylono-1,4-lactone-forming)
EC 1.1.1.425: levoglucosan dehydrogenase
EC 1.1.1.426: UDP-N-acetyl-α-D-quinovosamine dehydrogenase

EC 1.1.2 With a cytochrome as acceptor

EC 1.1.2.1: glycerolphosphate dehydrogenase. As the acceptor is now known, the enzyme has been transferred to EC 1.1.5.3, glycerol-3-phosphate dehydrogenase.
EC 1.1.2.2: mannitol dehydrogenase (cytochrome)
EC 1.1.2.3: L-lactate dehydrogenase (cytochrome)
EC 1.1.2.4: D-lactate dehydrogenase (cytochrome)
EC 1.1.2.5: D-lactate dehydrogenase (cytochrome c-553)
EC 1.1.2.6: polyvinyl alcohol dehydrogenase (cytochrome)
EC 1.1.2.7: methanol dehydrogenase (cytochrome c)
EC 1.1.2.8: alcohol dehydrogenase (cytochrome c)
EC 1.1.2.9: 1-butanol dehydrogenase (cytochrome c) *
EC 1.1.2.10: lanthanide-dependent methanol dehydrogenase *

*No Wikipedia article

EC 1.1.3 With oxygen as acceptor

EC 1.1.3.1: Now included with EC 1.1.3.15 (S)-2-hydroxy-acid oxidase
EC 1.1.3.2: L-lactate oxidase *
EC 1.1.3.3: malate oxidase
EC 1.1.3.4: glucose oxidase
EC 1.1.3.5: hexose oxidase
EC 1.1.3.6: cholesterol oxidase
EC 1.1.3.7: aryl-alcohol oxidase
EC 1.1.3.8: L-gulonolactone oxidase
EC 1.1.3.9: galactose oxidase
EC 1.1.3.10: pyranose oxidase
EC 1.1.3.11: L-sorbose oxidase
EC 1.1.3.12: pyridoxine 4-oxidase
EC 1.1.3.13: alcohol oxidase
EC 1.1.3.14: catechol oxidase (dimerizing)
EC 1.1.3.15: (S)-2-hydroxy-acid oxidase
EC 1.1.3.16: ecdysone oxidase
EC 1.1.3.17: choline oxidase
EC 1.1.3.18: Secondary-alcohol oxidase
EC 1.1.3.19: 4-hydroxymandelate oxidase
EC 1.1.3.20: long-chain-alcohol oxidase
EC 1.1.3.21: glycerol-3-phosphate oxidase
EC 1.1.3.22: Now EC 1.17.3.2, xanthine oxidase. The enzyme was incorrectly classified as acting on a CH-OH group
EC 1.1.3.23: Thiamine oxidase
EC 1.1.3.24: L-galactonolactone oxidase
EC 1.1.3.25: Now included with EC 1.1.99.18, cellobiose dehydrogenase (acceptor)
EC 1.1.3.26: Now EC 1.21.3.2, columbamine oxidase
EC 1.1.3.27: hydroxyphytanate oxidase
EC 1.1.3.28: nucleoside oxidase
EC 1.1.3.29: N-acylhexosamine oxidase
EC 1.1.3.30: polyvinyl-alcohol oxidase
EC 1.1.3.31: deleted, cannot be distinguished from EC 1.1.3.13, alcohol oxidase
EC 1.1.3.32: Now EC 1.14.21.1, (S)-stylopine synthase
EC 1.1.3.33: Now EC 1.14.21.2, (S)-cheilanthifoline synthase
EC 1.1.3.34: Now EC 1.14.21.3, berbamunine synthase
EC 1.1.3.35: Now EC 1.14.21.4, salutaridine synthase
EC 1.1.3.36: Now EC 1.14.21.5, (S)-canadine synthase
EC 1.1.3.37: D-arabinono-1,4-lactone oxidase
EC 1.1.3.38: vanillyl-alcohol oxidase
EC 1.1.3.39: nucleoside oxidase (H₂O₂-forming)
EC 1.1.3.40: D-mannitol oxidase
EC 1.1.3.41: xylitol oxidase
EC 1.1.3.42: prosolanapyrone-II oxidase
EC 1.1.3.43: paromamine 6′-oxidase
EC 1.1.3.44: 6′′′-hydroxyneomycin C oxidase
EC 1.1.3.45: aclacinomycin-N oxidase *
EC 1.1.3.46: 4-hydroxymandelate oxidase *
EC 1.1.3.47: 5-(hydroxymethyl)furfural oxidase *
EC 1.1.3.48: 3-deoxy-α-D-manno-octulosonate 8-oxidase *
EC 1.1.3.49: (R)-mandelonitrile oxidase *

*No Wikipedia article

EC 1.1.4 With a disulfide as acceptor

EC 1.1.4.1: Now EC 1.17.4.4, vitamin-K-epoxide reductase (warfarin-sensitive)
EC 1.1.4.2: Now EC 1.17.4.5, vitamin-K-epoxide reductase (warfarin-insensitive)

EC 1.1.5 With a quinone or similar compound as acceptor

EC 1.1.5.1: deleted, see EC 1.1.99.18 cellobiose dehydrogenase (acceptor)
EC 1.1.5.2: quinoprotein glucose dehydrogenase
EC 1.1.5.3: glycerol-3-phosphate dehydrogenase (quinone)
EC 1.1.5.4: malate dehydrogenase (quinone)
EC 1.1.5.5: alcohol dehydrogenase (quinone)
EC 1.1.5.6: formate dehydrogenase-N
EC 1.1.5.7: cyclic alcohol dehydrogenase (quinone)
EC 1.1.5.8: quinate dehydrogenase (quinone)

EC 1.1.9 With a copper protein as acceptor

EC 1.1.9.1: alcohol dehydrogenase (azurin)

EC 1.1.98 With other, known, acceptors

EC 1.1.98.1: Now EC 1.1.9.1, alcohol dehydrogenase (azurin)
EC 1.1.98.2: glucose-6-phosphate dehydrogenase (coenzyme-F₄₂₀)
EC 1.1.98.3: decaprenylphospho-β-D-ribofuranose 2-oxidase
EC 1.1.98.3: decaprenylphospho-β-D-ribofuranose 2-dehydrogenase *
EC 1.1.98.4: F₄₂₀H₂:quinone oxidoreductase *
EC 1.1.98.5: secondary-alcohol dehydrogenase (coenzyme-F₄₂₀) *
EC 1.1.98.6: ribonucleoside-triphosphate reductase (formate) *
EC 1.1.98.7: serine-type anaerobic sulfatase-maturating enzyme *

*No Wikipedia article

EC 1.1.99 With unknown physiological acceptors

EC 1.1.99.1: choline dehydrogenase
EC 1.1.99.2: L-2-hydroxyglutarate dehydrogenase
EC 1.1.99.3: gluconate 2-dehydrogenase (acceptor)
EC 1.1.99.4: dehydrogluconate dehydrogenase
EC 1.1.99.5: now EC 1.1.5.3, glycerol-3-phosphate dehydrogenase
EC 1.1.99.6: D-2-hydroxy-acid dehydrogenase
EC 1.1.99.7: lactate—malate transhydrogenase
EC 1.1.99.8: Now EC 1.1.2.7, methanol dehydrogenase (cytochrome c) and EC 1.1.2.8, alcohol dehydrogenase (cytochrome c).
EC 1.1.99.9: pyridoxine 5-dehydrogenase
EC 1.1.99.10: Now EC 1.1.5.9, glucose 1-dehydrogenase (FAD, quinone)
EC 1.1.99.11: Now classified as EC 1.1.5.14, fructose 5-dehydrogenase
EC 1.1.99.12: sorbose dehydrogenase
EC 1.1.99.13: glucoside 3-dehydrogenase
EC 1.1.99.14: glycolate dehydrogenase
EC 1.1.99.15: Now EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.1.99.16: Now EC EC 1.1.5.4, malate dehydrogenase (quinone)
EC 1.1.99.17: Now EC 1.1.5.2, quinoprotein glucose dehydrogenase
EC 1.1.99.18: cellobiose dehydrogenase (acceptor)
EC 1.1.99.19: Now EC 1.17.99.4, uracil/thymine dehydrogenase
EC 1.1.99.20: alkan-1-ol dehydrogenase (acceptor)
EC 1.1.99.21: D-sorbitol dehydrogenase (acceptor)
EC 1.1.99.22: glycerol dehydrogenase (acceptor)
EC 1.1.99.23: Now EC 1.1.2.6, polyvinyl alcohol dehydrogenase (cytochrome)
EC 1.1.99.24: hydroxyacid-oxoacid transhydrogenase
EC 1.1.99.25: Now EC 1.1.5.8, quinate dehydrogenase (quinone),
EC 1.1.99.26: 3-hydroxycyclohexanone dehydrogenase
EC 1.1.99.27: (R)-pantolactone dehydrogenase (flavin)
EC 1.1.99.28: glucose-fructose oxidoreductase
EC 1.1.99.29: pyranose dehydrogenase (acceptor)
EC 1.1.99.30: 2-oxoacid reductase
EC 1.1.99.31: (S)-mandelate dehydrogenase
EC 1.1.99.32: L-sorbose 1-dehydrogenase
EC 1.1.99.33: Now EC 1.17.99.7, formate dehydrogenase (acceptor)
EC 1.1.99.34: now EC 1.1.98.2, glucose-6-phosphate dehydrogenase (coenzyme-F₄₂₀)
EC 1.1.99.35: soluble quinoprotein glucose dehydrogenase
EC 1.1.99.36: alcohol dehydrogenase (nicotinoprotein)
EC 1.1.99.37: methanol dehydrogenase (nicotinoprotein)
EC 1.1.99.38: 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
EC 1.1.99.39: D-2-hydroxyglutarate dehydrogenase
EC 1.1.99.40: (R)-2-hydroxyglutarate—pyruvate transhydrogenase *
EC 1.1.99.41: 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase *
EC 1.1.99.42: 4-pyridoxic acid dehydrogenase *

*No Wikipedia article

EC 1.2 Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.2.1.1: deleted, replaced by EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase and EC 4.4.1.22, S-(hydroxymethyl)glutathione synthase
EC 1.2.1.2: Now EC 1.17.1.9, formate dehydrogenase
EC 1.2.1.3: aldehyde dehydrogenase (NAD⁺)
EC 1.2.1.4: aldehyde dehydrogenase (NADP⁺)
EC 1.2.1.5: aldehyde dehydrogenase (NAD(P)⁺)
EC 1.2.1.6: deleted (was benzaldehyde dehydrogenase)
EC 1.2.1.7: benzaldehyde dehydrogenase (NADP⁺)
EC 1.2.1.8: betaine-aldehyde dehydrogenase
EC 1.2.1.9: glyceraldehyde-3-phosphate dehydrogenase (NADP⁺)
EC 1.2.1.10: acetaldehyde dehydrogenase (acetylating)
EC 1.2.1.11: aspartate-semialdehyde dehydrogenase
EC 1.2.1.12: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
EC 1.2.1.13: glyceraldehyde-3-phosphate dehydrogenase (NADP⁺) (phosphorylating)
EC 1.2.1.14: Now EC 1.1.1.205, IMP dehydrogenase
EC 1.2.1.15: malonate-semialdehyde dehydrogenase
EC 1.2.1.16: succinate-semialdehyde dehydrogenase [NAD(P)⁺]
EC 1.2.1.17: glyoxylate dehydrogenase (acylating)
EC 1.2.1.18: malonate-semialdehyde dehydrogenase (acetylating)
EC 1.2.1.19: aminobutyraldehyde dehydrogenase
EC 1.2.1.20: glutarate-semialdehyde dehydrogenase
EC 1.2.1.21: glycolaldehyde dehydrogenase
EC 1.2.1.22: lactaldehyde dehydrogenase
EC 1.2.1.23: 2-oxoaldehyde dehydrogenase (NAD⁺)
EC 1.2.1.24: succinate-semialdehyde dehydrogenase (NAD⁺)
EC 1.2.1.25: branched-chain α-keto acid dehydrogenase system
EC 1.2.1.26: 2,5-dioxovalerate dehydrogenase
EC 1.2.1.27: methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
EC 1.2.1.28: benzaldehyde dehydrogenase (NAD⁺)
EC 1.2.1.29: aryl-aldehyde dehydrogenase
EC 1.2.1.30: carboxylate reductase (NADP⁺)
EC 1.2.1.31: L-aminoadipate-semialdehyde dehydrogenase
EC 1.2.1.32: aminomuconate-semialdehyde dehydrogenase
EC 1.2.1.33: (R)-dehydropantoate dehydrogenase
EC 1.2.1.34: Now EC 1.1.1.131, mannuronate reductase
EC 1.2.1.35: Now EC 1.1.1.203, uronate dehydrogenase
EC 1.2.1.36: retinal dehydrogenase
EC 1.2.1.37: Now EC 1.17.1.4, xanthine dehydrogenase
EC 1.2.1.38: N-acetyl-γ-glutamyl-phosphate reductase
EC 1.2.1.39: phenylacetaldehyde dehydrogenase
EC 1.2.1.40: part of EC 1.14.13.15, cholestanetriol 26-monooxygenase
EC 1.2.1.41: glutamate-5-semialdehyde dehydrogenase
EC 1.2.1.42: hexadecanal dehydrogenase (acylating)
EC 1.2.1.43: Now EC 1.17.1.10, formate dehydrogenase (NADP⁺)
EC 1.2.1.44: cinnamoyl-CoA reductase
EC 1.2.1.45: Now EC 1.1.1.312, 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
EC 1.2.1.46: formaldehyde dehydrogenase
EC 1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase
EC 1.2.1.48: long-chain-aldehyde dehydrogenase
EC 1.2.1.49: 2-oxoaldehyde dehydrogenase (NADP⁺)
EC 1.2.1.50: long-chain-fatty-acyl-CoA reductase
EC 1.2.1.51: pyruvate dehydrogenase (NADP⁺)
EC 1.2.1.52: oxoglutarate dehydrogenase (NADP⁺)
EC 1.2.1.53: 4-hydroxyphenylacetaldehyde dehydrogenase
EC 1.2.1.54: γ-guanidinobutyraldehyde dehydrogenase
EC 1.2.1.55: Now EC 1.1.1.279, (R)-3-hydroxyacid-ester dehydrogenase
EC 1.2.1.56: Now EC 1.1.1.280, (S)-3-hydroxyacid-ester dehydrogenase
EC 1.2.1.57: butanal dehydrogenase
EC 1.2.1.58: phenylglyoxylate dehydrogenase (acylating)
EC 1.2.1.59: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)⁺)
EC 1.2.1.60: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
EC 1.2.1.61: 4-hydroxymuconic-semialdehyde dehydrogenase
EC 1.2.1.62: 4-formylbenzenesulfonate dehydrogenase
EC 1.2.1.63: 6-oxohexanoate dehydrogenase
EC 1.2.1.64: 4-hydroxybenzaldehyde dehydrogenase (NAD⁺)
EC 1.2.1.65: salicylaldehyde dehydrogenase
EC 1.2.1.66: Now EC 1.1.1.306, S-(hydroxymethyl)mycothiol dehydrogenase]]
EC 1.2.1.67: vanillin dehydrogenase
EC 1.2.1.68: coniferyl-aldehyde dehydrogenase
EC 1.2.1.69: fluoroacetaldehyde dehydrogenase
EC 1.2.1.70: glutamyl-tRNA reductase
EC 1.2.1.71: succinylglutamate-semialdehyde dehydrogenase
EC 1.2.1.72: erythrose-4-phosphate dehydrogenase
EC 1.2.1.73: sulfoacetaldehyde dehydrogenase
EC 1.2.1.74: abieta-7,13-dien-18-al dehydrogenase
EC 1.2.1.75: malonyl CoA reductase (malonate semialdehyde-forming)
EC 1.2.1.76: succinate-semialdehyde dehydrogenase (acylating)
EC 1.2.1.77: 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP⁺)
EC 1.2.1.78: 2-formylbenzoate dehydrogenase
EC 1.2.1.79: succinate-semialdehyde dehydrogenase (NADP⁺)
EC 1.2.1.80: long-chain acyl-[acyl-carrier-protein] reductase
EC 1.2.1.81: sulfoacetaldehyde dehydrogenase (acylating)
EC 1.2.1.82: β-apo-4′-carotenal oxygenase
EC 1.2.1.83: 3-succinoylsemialdehyde-pyridine dehydrogenase
EC 1.2.1.84: alcohol-forming fatty acyl-CoA reductase
EC 1.2.1.85: 2-hydroxymuconate-6-semialdehyde dehydrogenase
EC 1.2.1.86: geranial dehydrogenase
EC 1.2.1.87: propanal dehydrogenase (CoA-propanoylating) *
EC 1.2.1.88: L-glutamate γ-semialdehyde dehydrogenase *
EC 1.2.1.89: D-glyceraldehyde dehydrogenase (NADP⁺) *
EC 1.2.1.90: glyceraldehyde-3-phosphate dehydrogenase [NAD(P)⁺] *
EC 1.2.1.91: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase *
EC 1.2.1.92: 3,6-anhydro-α-L-galactose dehydrogenase *
EC 1.2.1.93: formate dehydrogenase (NAD+, ferredoxin). Now EC 1.17.1.11, formate dehydrogenase (NAD⁺, ferredoxin) *
EC 1.2.1.94: farnesal dehydrogenase *
EC 1.2.1.95: L-2-aminoadipate reductase *
EC 1.2.1.96: 4-hydroxybenzaldehyde dehydrogenase (⁺+) *
EC 1.2.1.97: 3-sulfolactaldehyde dehydrogenase *
EC 1.2.1.98: 2-hydroxy-2-methylpropanal dehydrogenase *
EC 1.2.1.99: 4-(γ-glutamylamino)butanal dehydrogenase *
EC 1.2.1.100: 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase *
EC 1.2.1.101: L-tyrosine reductase *
EC 1.2.1.102: isopyridoxal dehydrogenase (5-pyridoxate-forming) *
EC 1.2.1.103: [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase *
EC 1.2.1.104: pyruvate dehydrogenase system *
EC 1.2.1.105: 2-oxoglutarate dehydrogenase system *
EC 1.2.1.106: [amino-group carrier protein]-5-phospho-L-glutamate reductase *
EC 1.2.1.107: glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring) *

* No Wikipedia article

EC 1.2.2 With a cytochrome as acceptor

EC 1.2.2.1: formate dehydrogenase (cytochrome)
EC 1.2.2.2: Now covered by EC 1.2.5.1, pyruvate dehydrogenase (quinone)
EC 1.2.2.3: Now EC 1.17.2.3, formate dehydrogenase (cytochrome-c-553)
EC 1.2.2.4: Now classified as EC 1.2.5.3, aerobic carbon monoxide dehydrogenase

EC 1.2.3 With oxygen as acceptor

EC 1.2.3.1: aldehyde oxidase
EC 1.2.3.2: Now EC 1.17.3.2, xanthine oxidase
EC 1.2.3.3: pyruvate oxidase
EC 1.2.3.4: oxalate oxidase
EC 1.2.3.5: glyoxylate oxidase
EC 1.2.3.6: pyruvate oxidase (CoA-acetylating)
EC 1.2.3.7: indole-3-acetaldehyde oxidase
EC 1.2.3.8: pyridoxal oxidase
EC 1.2.3.9: aryl-aldehyde oxidase
EC 1.2.3.10: deleted, activity due to EC 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome b-561)
EC 1.2.3.11: retinal oxidase
EC 1.2.3.12: Now included with EC 1.2.3.1, aldehyde oxidase
EC 1.2.3.13: Now EC 1.14.13.82, vanillate monooxygenase
EC 1.2.3.14: Abscisic-aldehyde oxidase
EC 1.2.3.15: (methyl)glyoxal oxidase *

* No Wikipedia article

EC 1.2.4 With a disulfide as acceptor

EC 1.2.4.1: pyruvate dehydrogenase (acetyl-transferring)
EC 1.2.4.2: oxoglutarate dehydrogenase (succinyl-transferring)
EC 1.2.4.3: Now included with EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
EC 1.2.4.4: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)

EC 1.2.5 With a quinone or similar compound as acceptor

EC 1.2.5.1: pyruvate dehydrogenase (quinone)
EC 1.2.5.2: aldehyde dehydrogenase (quinone) *
EC 1.2.5.3: aerobic carbon monoxide dehydrogenase *

*No Wikipedia article

EC 1.2.7 With an iron–sulfur protein as acceptor

EC 1.2.7.1: pyruvate synthase
EC 1.2.7.2: Now included with EC 1.2.7.1, pyruvate synthase.
EC 1.2.7.3: 2-oxoglutarate synthase
EC 1.2.7.4: anaerobic carbon monoxide dehydrogenase
EC 1.2.7.5: aldehyde ferredoxin oxidoreductase
EC 1.2.7.6: glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)
EC 1.2.7.7: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
EC 1.2.7.8: indolepyruvate ferredoxin oxidoreductase
EC 1.2.7.9: deleted, identical to EC 1.2.7.3, 2-oxoglutarate synthase
EC 1.2.7.10: oxalate oxidoreductase
EC 1.2.7.11: 2-oxoacid oxidoreductase (ferredoxin) *
EC 1.2.7.12: formylmethanofuran dehydrogenase *

*No Wikipedia article

EC 1.2.99: With unknown physiological acceptors

EC 1.2.99.1: Now EC 1.17.99.4, uracil/thymine dehydrogenase
EC 1.2.99.2: Now EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin)
EC 1.2.99.3: Now EC 1.2.5.2, aldehyde dehydrogenase (quinone)
EC 1.2.99.4: Now EC 1.2.98.1, formaldehyde dismutase
EC 1.2.99.5: Now EC 1.2.7.12, formylmethanofuran dehydrogenase
EC 1.2.99.6: carboxylate reductase
EC 1.2.99.7: aldehyde dehydrogenase (FAD-independent)
EC 1.2.99.8: glyceraldehyde dehydrogenase (FAD-containing) *
EC 1.2.99.9: Now EC 1.17.98.3, formate dehydrogenase (coenzyme F₄₂₀)
EC 1.2.99.10: 4,4′-diapolycopenoate synthase *

*No Wikipedia article

EC 1.3 Acting on the CH-CH group of donors

EC 1.3.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.3.1.1: dihydrouracil dehydrogenase (NAD⁺)
EC 1.3.1.2: dihydropyrimidine dehydrogenase (NADP⁺)
EC 1.3.1.3: Δ⁴-3-oxosteroid 5β-reductase
EC 1.3.1.4: transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺)
EC 1.3.1.5: cucurbitacin Δ²³-reductase
EC 1.3.1.6: fumarate reductase (NADH)
EC 1.3.1.7: meso-tartrate dehydrogenase
EC 1.3.1.8: acyl-CoA dehydrogenase (NADP⁺)
EC 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH)
EC 1.3.1.10: enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
EC 1.3.1.11: 2-coumarate reductase
EC 1.3.1.12: prephenate dehydrogenase
EC 1.3.1.13: prephenate dehydrogenase (NADP⁺)
EC 1.3.1.14: dihydroorotate dehydrogenase (NAD⁺)
EC 1.3.1.15: dihydroorotate dehydrogenase (NADP⁺)
EC 1.3.1.16: β-nitroacrylate reductase
EC 1.3.1.17: 3-methyleneoxindole reductase
EC 1.3.1.18: kynurenate-7,8-dihydrodiol dehydrogenase
EC 1.3.1.19: cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.20: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.21: 7-dehydrocholesterol reductase
EC 1.3.1.22: 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺)
EC 1.3.1.23: identical to EC 1.3.1.3, Δ4-3-oxosteroid 5β-reductase
EC 1.3.1.24: biliverdin reductase
EC 1.3.1.25: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
EC 1.3.1.26: Now EC 1.17.1.8, 4-hydroxy-tetrahydrodipicolinate reductase
EC 1.3.1.27: 2-hexadecenal reductase
EC 1.3.1.28: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
EC 1.3.1.29: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
EC 1.3.1.30: transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺)
EC 1.3.1.31: 2-enoate reductase
EC 1.3.1.32: maleylacetate reductase
EC 1.3.1.33: protochlorophyllide reductase
EC 1.3.1.34: 2,4-dienoyl-CoA reductase (NADPH)|2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
EC 1.3.1.35: Now EC 1.14.19.22, microsomal oleoyl-lipid 12-desaturase
EC 1.3.1.36: geissoschizine dehydrogenase
EC 1.3.1.37: cis-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.38: trans-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.39: trans-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.40: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
EC 1.3.1.41: xanthommatin reductase
EC 1.3.1.42: 12-oxophytodienoate reductase
EC 1.3.1.43: arogenate dehydrogenase
EC 1.3.1.44: trans-2-enoyl-CoA reductase (NAD⁺)
EC 1.3.1.45: 2′-hydroxyisoflavone reductase
EC 1.3.1.46: biochanin-A reductase
EC 1.3.1.47: α-santonin 1,2-reductase
EC 1.3.1.48: 13,14-dehydro-15-oxoprostaglandin 13-reductase
EC 1.3.1.49: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
EC 1.3.1.50: n Now EC 1.1.1.252 tetrahydroxynaphthalene reductase
EC 1.3.1.51: 2′-hydroxydaidzein reductase
EC 1.3.1.52: Now EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.1.53: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
EC 1.3.1.54: precorrin-6A reductase
EC 1.3.1.55: identical to EC 1.3.1.25, 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
EC 1.3.1.56: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
EC 1.3.1.57: phloroglucinol reductase
EC 1.3.1.58: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
EC 1.3.1.59: There is no evidence that the enzyme exists
EC 1.3.1.60: dibenzothiophene dihydrodiol dehydrogenase
EC 1.3.1.61: identical to EC 1.3.1.53, (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
EC 1.3.1.62: pimeloyl-CoA dehydrogenase
EC 1.3.1.63: Now EC 1.21.1.2, 2,4-dichlorobenzoyl-CoA reductase
EC 1.3.1.64: phthalate 4,5-cis-dihydrodiol dehydrogenase
EC 1.3.1.65: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
EC 1.3.1.66: cis-dihydroethylcatechol dehydrogenase
EC 1.3.1.67: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
EC 1.3.1.68: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
EC 1.3.1.69: zeatin reductase
EC 1.3.1.70: Δ¹⁴-sterol reductase
EC 1.3.1.71: Δ^24(24¹)-sterol reductase
EC 1.3.1.72: Δ²⁴-sterol reductase
EC 1.3.1.73: 1,2-dihydrovomilenine reductase
EC 1.3.1.74: 2-alkenal reductase [NAD(P)⁺]
EC 1.3.1.75: 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
EC 1.3.1.76: precorrin-2 dehydrogenase
EC 1.3.1.77: anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
EC 1.3.1.78: arogenate dehydrogenase (NADP⁺)
EC 1.3.1.79: arogenate dehydrogenase (NAD(P)⁺)
EC 1.3.1.80: Now classified as EC 1.3.7.12, red chlorophyll catabolite reductase
EC 1.3.1.81: (+)-pulegone reductase
EC 1.3.1.82: (-)-isopiperitenone reductase
EC 1.3.1.83: geranylgeranyl diphosphate reductase
EC 1.3.1.84: acrylyl-CoA reductase (NADPH)
EC 1.3.1.85: crotonyl-CoA carboxylase/reductase
EC 1.3.1.86: crotonyl-CoA reductase
EC 1.3.1.87: 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase
EC 1.3.1.88: tRNA-dihydrouridine^16/17 synthase (NAD(P)⁺)
EC 1.3.1.89: tRNA-dihydrouridine⁴⁷ synthase (NAD(P)⁺)
EC 1.3.1.90: tRNA-dihydrouridine^20a/20b synthase (NAD(P)⁺)
EC 1.3.1.91: tRNA-dihydrouridine²⁰ synthase (NAD(P)⁺)
EC 1.3.1.92: artemisinic aldehyde Δ¹¹⁽¹³⁾-reductase
EC 1.3.1.93: very-long-chain enoyl-CoA reductase
EC 1.3.1.94: polyprenol reductase
EC 1.3.1.95: acrylyl-CoA reductase (NADH)
EC 1.3.1.96: Botryococcus squalene synthase
EC 1.3.1.97: botryococcene synthase
EC 1.3.1.98: Now known to be catalyzed by two different enzymes, EC 1.3.1.122, (S)-8-oxocitronellyl enol synthase, and EC 5.5.1.34, (+)-cis,trans-nepetalactol synthase
EC 1.3.1.100: chanoclavine-I aldehyde reductase *
EC 1.3.1.101: 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H] *
EC 1.3.1.102: 2-alkenal reductase (NADP+) *
EC 1.3.1.103: 2-haloacrylate reductase *
EC 1.3.1.104: enoyl-[acyl-carrier-protein] reductase (NADPH) *
EC 1.3.1.105: 2-methylene-furan-3-one reductase *
EC 1.3.1.106: cobalt-precorrin-6A reductase *
EC 1.3.1.107: sanguinarine reductase *
EC 1.3.1.108: caffeoyl-CoA reductase *
EC 1.3.1.109: butanoyl-CoA dehydrogenase complex (NAD⁺, ferredoxin) *
EC 1.3.1.110: lactate dehydrogenase (NAD⁺,ferredoxin) *
EC 1.3.1.111: geranylgeranyl-bacteriochlorophyllide a reductase *
EC 1.3.1.112: anthocyanidin reductase [(2S)-flavan-3-ol-forming] *
EC 1.3.1.113: (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase *
EC 1.3.1.114: 3-dehydro-bile acid Δ^4,6-reductase *
EC 1.3.1.115: 3-oxocholoyl-CoA 4-desaturase *
EC 1.3.1.116: 7β-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase *
EC 1.3.1.117: hydroxycinnamoyl-CoA reductase *
EC 1.3.1.118: meromycolic acid enoyl-[acyl-carrier-protein] reductase *
EC 1.3.1.119: chlorobenzene dihydrodiol dehydrogenase *
EC 1.3.1.120: cyclohexane-1-carbonyl-CoA reductase NADP⁺) *
EC 1.3.1.121: 4-amino-4-deoxyprephenate dehydrogenase *
EC 1.3.1.122: (S)-8-oxocitronellyl enol synthase *
EC 1.3.1.123: 8-oxogeranial reductase *
EC 1.3.1.124: 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] *

*No Wikipedia article

EC 1.3.2 With a cytochrome as acceptor

EC 1.3.2.1: now EC 1.3.99.2
EC 1.3.2.2: now EC 1.3.99.3
EC 1.3.2.3: galactonolactone dehydrogenase

EC 1.3.3 With oxygen as acceptor

EC 1.3.5 With a quinone or related compound as acceptor

EC 1.3.7 With an iron–sulfur protein as acceptor

EC 1.3.8 With a flavin as acceptor

EC 1.3.8.1: short-chain acyl-CoA dehydrogenase
EC 1.3.8.2: 4,4′-diapophytoene desaturase (4,4′-diapolycopene-forming)
EC 1.3.8.3: (R)-benzylsuccinyl-CoA dehydrogenase
EC 1.3.8.4: isovaleryl-CoA dehydrogenase
EC 1.3.8.5: 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.8.6: glutaryl-CoA dehydrogenase (ETF)
EC 1.3.8.7: medium-chain acyl-CoA dehydrogenase
EC 1.3.8.8: long-chain acyl-CoA dehydrogenase
EC 1.3.8.9: very-long-chain acyl-CoA dehydrogenase
EC 1.3.8.10: cyclohex-1-ene-1-carbonyl-CoA dehydrogenase *
EC 1.3.8.11: cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein) *
EC 1.3.8.12: (2S)-methylsuccinyl-CoA dehydrogenase *
EC 1.3.8.13: crotonobetainyl-CoA reductase *
EC 1.3.8.14: L-prolyl-[peptidyl-carrier protein] dehydrogenase *
EC 1.3.8.15: 3-(aryl)acrylate reductase *
EC 1.3.8.16: 2-amino-4-deoxychorismate dehydrogenase *
EC 1.3.8.17: dehydro coenzyme F₄₂₀ reductase *

*No Wikipedia article

EC 1.3.98 With FMN acceptor

EC 1.3.98.1: dihydroorotate dehydrogenase (fumarate)
EC 1.3.98.2: Now EC 1.3.4.1, fumarate reductase (CoM/CoB)
EC 1.3.98.3: coproporphyrinogen dehydrogenase *
EC 1.3.98.4: 5a,11a-dehydrotetracycline reductase *
EC 1.3.98.5: hydrogen peroxide-dependent heme synthase *
EC 1.3.98.6: AdoMet-dependent heme synthase *
EC 1.3.98.7: [mycofactocin precursor peptide]-tyrosine decarboxylase

*No Wikipedia article

EC 1.3.99 With unknown physiological acceptors

EC 1.3.99.1: The activity is included in EC 1.3.5.1, succinate dehydrogenase (quinone)
EC 1.3.99.2: Now EC 1.3.8.1, butyryl-CoA dehydrogenase.
EC 1.3.99.3: now EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, EC 1.3.8.8, long-chain acyl-CoA dehydrogenase and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase
EC 1.3.99.4: 3-oxosteroid 1-dehydrogenase
EC 1.3.99.5: 3-oxo-5α-steroid 4-dehydrogenase (acceptor)
EC 1.3.99.6: 3-oxo-5β-steroid 4-dehydrogenase
EC 1.3.99.7: Now EC 1.3.8.6, glutaryl-CoA dehydrogenase
EC 1.3.99.8: 2-furoyl-CoA dehydrogenase
EC 1.3.99.9: Now EC 1.21.99.1, β-cyclopiazonate dehydrogenase
EC 1.3.99.10: Now EC 1.3.8.4, isovaleryl-CoA dehydrogenase
EC 1.3.99.11: transferred to EC 1.3.5.2, dihydroorotate dehydrogenase
EC 1.3.99.12: Now classified as EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.99.13: Now EC 1.3.8.8, long-chain-acyl-CoA dehydrogenase
EC 1.3.99.14: cyclohexanone dehydrogenase
EC 1.3.99.15: Now EC 1.3.7.8
EC 1.3.99.16: isoquinoline 1-oxidoreductase
EC 1.3.99.17: quinoline 2-oxidoreductase
EC 1.3.99.18: quinaldate 4-oxidoreductase
EC 1.3.99.19: quinoline-4-carboxylate 2-oxidoreductase
EC 1.3.99.20: Now EC 1.3.7.9, 4-hydroxybenzoyl-CoA reductase
EC 1.3.99.21: Now EC 1.3.8.3, (R)-benzylsuccinyl-CoA dehydrogenase
EC 1.3.99.22: Now EC 1.3.98.3, coproporphyrinogen dehydrogenase
EC 1.3.99.23: all-trans-retinol 13,14-reductase
EC 1.3.99.24: Now EC 1.3.8.16, 2-amino-4-deoxychorismate dehydrogenase
EC 1.3.99.25: carvone reductase
EC 1.3.99.26: all-trans-ζ-carotene desaturase
EC 1.3.99.27: 1-hydroxycarotenoid 3,4-desaturase
EC 1.3.99.28: phytoene desaturase (neurosporene-forming)
EC 1.3.99.29: phytoene desaturase (zeta-carotene-forming)
EC 1.3.99.30: phytoene desaturase (3,4-didehydrolycopene-forming)
EC 1.3.99.31: phytoene desaturase (lycopene-forming)
EC 1.3.99.32: glutaryl-CoA dehydrogenase (non-decarboxylating)
EC 1.3.99.33: urocanate reductase *
EC 1.3.99.34: Now classified as EC 1.3.7.11, 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase
EC 1.3.99.35: Now EC 1.3.7.15, chlorophyllide a reductase *
EC 1.3.99.36: cypemycin cysteine dehydrogenase (decarboxylating) *
EC 1.3.99.37: 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase *
EC 1.3.99.38: menaquinone-9 β-reductase *
EC 1.3.99.39: carotenoid φ-ring synthase *
EC 1.3.99.40: carotenoid χ-ring synthase *

*No Wikipedia article

EC 1.4 Acting on the CH-NH₂ group of donors

EC 1.4.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.4.1.1: alanine dehydrogenase
EC 1.4.1.2: glutamate dehydrogenase
EC 1.4.1.3: glutamate dehydrogenase (NAD(P)⁺)
EC 1.4.1.4: glutamate dehydrogenase (NADP⁺)
EC 1.4.1.5: L-amino-acid dehydrogenase
EC 1.4.1.6: deleted, Now included with EC 1.21.4.1, D-proline reductase (dithiol)
EC 1.4.1.7: serine 2-dehydrogenase
EC 1.4.1.8: valine dehydrogenase (NADP⁺)
EC 1.4.1.9: leucine dehydrogenase
EC 1.4.1.10: glycine dehydrogenase
EC 1.4.1.11: L-erythro-3,5-diaminohexanoate dehydrogenase
EC 1.4.1.12: 2,4-diaminopentanoate dehydrogenase
EC 1.4.1.13: glutamate synthase (NADPH)
EC 1.4.1.14: glutamate synthase (NADH)
EC 1.4.1.15: lysine dehydrogenase
EC 1.4.1.16: diaminopimelate dehydrogenase
EC 1.4.1.17: N-methylalanine dehydrogenase
EC 1.4.1.18: lysine 6-dehydrogenase
EC 1.4.1.19: tryptophan dehydrogenase
EC 1.4.1.20: phenylalanine dehydrogenase
EC 1.4.1.21: aspartate dehydrogenase
EC 1.4.1.22: there is no overall consumption of NAD⁺ during the reaction. As a result, transfer of the enzyme from EC 4.3.1.12 was not necessary and EC 1.4.1.22 was withdrawn before being made official
EC 1.4.1.23: valine dehydrogenase (NAD⁺)
EC 1.4.1.24: 3-dehydroquinate synthase II
EC 1.4.1.25: L-arginine dehydrogenase *
EC 1.4.1.26: 2,4-diaminopentanoate dehydrogenase (NAD⁺) *
EC 1.4.1.27: glycine cleavage system *

*No Wikipedia article

EC 1.4.2 With a cytochrome as acceptor

EC 1.4.2.1: glycine dehydrogenase (cytochrome)

EC 1.4.3 With oxygen as acceptor

EC 1.4.3.1: D-aspartate oxidase
EC 1.4.3.2: L-amino-acid oxidase
EC 1.4.3.3: D-amino-acid oxidase
EC 1.4.3.4: monoamine oxidase
EC 1.4.3.5: pyridoxal 5′-phosphate synthase
EC 1.4.3.6: replaced by two enzymes, EC 1.4.3.21 (primary-amine oxidase) and EC 1.4.3.22 (diamine oxidase)
EC 1.4.3.7: D-glutamate oxidase
EC 1.4.3.8: ethanolamine oxidase
EC 1.4.3.9: Now included with EC 1.4.3.4 amine oxidase (flavin-containing)
EC 1.4.3.10: putrescine oxidase
EC 1.4.3.11: L-glutamate oxidase
EC 1.4.3.12: cyclohexylamine oxidase
EC 1.4.3.13: protein-lysine 6-oxidase
EC 1.4.3.14: L-lysine oxidase
EC 1.4.3.15: D-glutamate(D-aspartate) oxidase
EC 1.4.3.16: L-aspartate oxidase
EC 1.4.3.17: Now EC 1.3.3.10, tryptophan α,β-oxidase
EC 1.4.3.18: Not approved as the enzyme was shown to be a dehydrogenase and not an oxidase (see EC 1.5.99.12, cytokinin dehydrogenase)
EC 1.4.3.19: glycine oxidase
EC 1.4.3.20: L-lysine 6-oxidase
EC 1.4.3.21: primary-amine oxidase
EC 1.4.3.22: diamine oxidase
EC 1.4.3.23: 7-chloro-L-tryptophan oxidase
EC 1.4.3.24: pseudooxynicotine oxidase
EC 1.4.3.25: L-arginine oxidase *
EC 1.4.3.26: pre-mycofactocin synthase *

*No Wikipedia article

EC 1.4.4 With a disulfide as acceptor

EC 1.4.4.1: Now EC 1.21.4.1, D-proline reductase (dithiol)
EC 1.4.4.2: glycine dehydrogenase (aminomethyl-transferring)

EC 1.4.5 With a quinone or other compound as acceptor

EC 1.4.5.1: D-amino acid dehydrogenase (quinone)

EC 1.4.7 With an iron–sulfur protein as acceptor

EC 1.4.7.1: glutamate synthase (ferredoxin)

EC 1.4.9 With a copper protein as acceptor

EC 1.4.98 With tryptophan tryptophylquinone acceptors

EC 1.4.98.1: methylamine dehydrogenase (amicyanin)

EC 1.4.99 With unknown physiological acceptors

EC 1.4.99.1: Now lEC 1.4.99.6, D-arginine dehydrogenase
EC 1.4.99.2: taurine dehydrogenase
EC 1.4.99.3: Now EC 1.4.9.1, methylamine dehydrogenase (amicyanin)
EC 1.4.99.4: Now EC 1.4.9.2, aralkylamine dehydrogenase (azurin)
EC 1.4.99.5: glycine dehydrogenase (cyanide-forming)
EC 1.4.99.6: D-arginine dehydrogenase *

*No Wikipedia article

EC 1.5 Acting on the CH-NH group of donors

EC 1.5.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.5.1.1: 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H
EC 1.5.1.2: pyrroline-5-carboxylate reductase
EC 1.5.1.3: dihydrofolate reductase
EC 1.5.1.4: Now included with EC 1.5.1.3 dihydrofolate reductase
EC 1.5.1.5: methylenetetrahydrofolate dehydrogenase (NADP⁺)
EC 1.5.1.6: formyltetrahydrofolate dehydrogenase
EC 1.5.1.7: saccharopine dehydrogenase (NAD⁺, L-lysine-forming)
EC 1.5.1.8: saccharopine dehydrogenase (NADP⁺, L-lysine-forming)
EC 1.5.1.9: saccharopine dehydrogenase (NAD⁺, L-glutamate-forming)
EC 1.5.1.10: saccharopine dehydrogenase (NADP⁺, L-glutamate-forming)
EC 1.5.1.11: D-octopine dehydrogenase
EC 1.5.1.12: Now EC 1.2.1.88, L-glutamate γ-semialdehyde dehydrogenase
EC 1.5.1.13: Now EC 1.17.1.5, nicotinate dehydrogenase
EC 1.5.1.14: Now included with EC 1.5.1.21 Δ¹-piperideine-2-carboxylate reductase
EC 1.5.1.15: methylenetetrahydrofolate dehydrogenase (NAD⁺)
EC 1.5.1.16: D-lysopine dehydrogenase
EC 1.5.1.17: alanopine dehydrogenase
EC 1.5.1.18: ephedrine dehydrogenase
EC 1.5.1.19: D-nopaline dehydrogenase
EC 1.5.1.20: methylenetetrahydrofolate reductase (NAD(P)H)
EC 1.5.1.21: 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
EC 1.5.1.22: strombine dehydrogenase
EC 1.5.1.23: tauropine dehydrogenase
EC 1.5.1.24: N⁵-(carboxyethyl)ornithine synthase
EC 1.5.1.25: thiomorpholine-carboxylate dehydrogenase
EC 1.5.1.26: β-alanopine dehydrogenase
EC 1.5.1.27: 1,2-dehydroreticulinium reductase (NADPH)
EC 1.5.1.28: opine dehydrogenase
EC 1.5.1.29: Now covered by EC 1.5.1.38 [FMN reductase (NADPH)], EC 1.5.1.39 [FMN reductase [NAD(P)H])] and EC 1.5.1.41 (riboflavin reductase [NAD(P)H])
EC 1.5.1.30: flavin reductase (NADPH)
EC 1.5.1.31: berberine reductase
EC 1.5.1.32: vomilenine reductase
EC 1.5.1.33: pteridine reductase
EC 1.5.1.34: 6,7-dihydropteridine reductase
EC 1.5.1.35: identical to EC 1.2.1.19, aminobutyraldehyde dehydrogenase, as the substrates 1-pyrroline and 4-aminobutanal are interconvertible
EC 1.5.1.36: flavin reductase (NADH)
EC 1.5.1.37: FAD reductase (NADH)
EC 1.5.1.38: FMN reductase (NADPH)
EC 1.5.1.39: FMN reductase (NAD(P)H)
EC 1.5.1.40: 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
EC 1.5.1.41: riboflavin reductase (NAD(P)H)
EC 1.5.1.42: FMN reductase (NADH)
EC 1.5.1.43: carboxynorspermidine synthase
EC 1.5.1.44: festuclavine dehydrogenase
EC 1.5.1.45: FAD reductase (NAD(P)H)
EC 1.5.1.46: agroclavine dehydrogenase *
EC 1.5.1.47: dihydromethanopterin reductase [NAD(P)⁺] *
EC 1.5.1.48: 2-methyl-1-pyrroline reductase *
EC 1.5.1.49: 1-pyrroline-2-carboxylate reductase [NAD(P)H] *
EC 1.5.1.50: dihydromonapterin reductase *
EC 1.5.1.51: N-[(2S)-2-amino-2-carboxyethyl]-L-lutamate dehydrogenase *
EC 1.5.1.52: staphylopine dehydrogenase *
EC 1.5.1.53: methylenetetrahydrofolate reductase (NADPH) *
EC 1.5.1.54: methylenetetrahydrofolate reductase (NADH) *

*No Wikipedia article

EC 1.5.3 With oxygen as acceptor

EC 1.5.3.1: sarcosine oxidase
EC 1.5.3.2: N-methyl-L-amino-acid oxidase
EC 1.5.3.3: deleted
EC 1.5.3.4: N⁶-methyl-lysine oxidase
EC 1.5.3.5: (S)-6-hydroxynicotine oxidase
EC 1.5.3.6: (R)-6-hydroxynicotine oxidase
EC 1.5.3.7: L-pipecolate oxidase
EC 1.5.3.8: Now included with EC 1.3.3.8, tetrahydroberberine oxidase
EC 1.5.3.9: Now EC 1.21.3.3, reticuline oxidase
EC 1.5.3.10: dimethylglycine oxidase
EC 1.5.3.11: Now included with EC 1.5.3.13 (N¹-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.15 (N⁸-acetylspermidine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase)
EC 1.5.3.12: dihydrobenzophenanthridine oxidase
EC 1.5.3.13: N¹-acetylpolyamine oxidase
EC 1.5.3.14: polyamine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.15: N⁸-acetylspermidine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.16: spermine oxidase
EC 1.5.3.17: non-specific polyamine oxidase
EC 1.5.3.18: L-saccharopine oxidase
EC 1.5.3.19: 4-methylaminobutanoate oxidase (formaldehyde-forming)
EC 1.5.3.20: N-alkylglycine oxidase
EC 1.5.3.21: 4-methylaminobutanoate oxidase (methylamine-forming)
EC 1.5.3.22: coenzyme F₄₂₀H₂ oxidase *
EC 1.5.3.23: glyphosate oxidoreductase *

*No Wikipedia article

EC 1.5.4 With a disulfide as acceptor

EC 1.5.4.1: pyrimidodiazepine synthase

EC 1.5.5 With a quinone or similar compound as acceptor

EC 1.5.5.1: electron-transferring-flavoprotein dehydrogenase
EC 1.5.5.2: proline dehydrogenase *
EC 1.5.5.3: hydroxyproline dehydrogenase *

*No Wikipedia article

EC 1.5.7 With an iron–sulfur protein as acceptor

EC 1.5.7.1: methylenetetrahydrofolate reductase (ferredoxin)
EC 1.5.7.2: coenzyme F₄₂₀ oxidoreductase (ferredoxin) *

*No Wikipedia article

EC 1.5.8 With a flavin or flavoprotein as acceptor

EC 1.5.98 With other, known, physiological acceptors

EC 1.5.98.1: ethylenetetrahydromethanopterin dehydrogenase
EC 1.5.98.2: 5,10-methylenetetrahydromethanopterin reductase
EC 1.5.98.3: coenzyme F₄₂₀:methanophenazine dehydrogenase

EC 1.5.99 With unknown physiological acceptors

EC 1.5.99.1: Now EC 1.5.8.3, sarcosine dehydrogenase
EC 1.5.99.2: Now EC 1.5.8.4, dimethylglycine dehydrogenase
EC 1.5.99.3: L-pipecolate dehydrogenase
EC 1.5.99.4: nicotine dehydrogenase
EC 1.5.99.5: methylglutamate dehydrogenase
EC 1.5.99.6: spermidine dehydrogenase
EC 1.5.99.7: Now EC 1.5.8.2, trimethylamine dehydrogenase
EC 1.5.99.8: Now EC 1.5.5.2, proline dehydrogenase
EC 1.5.99.9: transferred to EC 1.5.98.1, methylenetetrahydromethanopterin dehydrogenase
EC 1.5.99.10: Now EC 1.5.8.1, dimethylamine dehydrogenase
EC 1.5.99.11: transferred to EC 1.5.98.2, 5,10-methylenetetrahydromethanopterin reductase
EC 1.5.99.12: cytokinin dehydrogenase
EC 1.5.99.13: D-proline dehydrogenase
EC 1.5.99.14: 6-hydroxypseudooxynicotine dehydrogenase
EC 1.5.99.15: dihydromethanopterin reductase (acceptor) *

*No Wikipedia article

EC 1.6 Acting on NADH or NADPH

EC 1.6.1 With NAD or NADP as acceptor

EC 1.6.2 With a heme protein as acceptor

EC 1.6.2.1: now EC 1.6.99.3 NADH dehydrogenase
EC 1.6.2.2: cytochrome-b₅ reductase
EC 1.6.2.3: deleted
EC 1.6.2.4: NADPH—hemoprotein reductase
EC 1.6.2.5: NADPH—cytochrome-c₂ reductase
EC 1.6.2.6: leghemoglobin reductase

EC 1.6.3 With oxygen as acceptor

EC 1.6.3.1: NAD(P)H oxidase (H₂O₂-forming)
EC 1.6.3.2: NAD(P)H oxidase (H₂O-forming) *
EC 1.6.3.3: NADH oxidase (H₂O₂-forming) *
EC 1.6.3.4: NADH oxidase (H₂O-forming) *
EC 1.6.3.5: renalase *

*No Wikipedia article

EC 1.6.4 With a disulfide as acceptor (deleted sub-class)

EC 1.6.4.1: now EC 1.8.1.6 cystine reductase
EC 1.6.4.2: now EC 1.8.1.7 glutathione-disulfide reductase
EC 1.6.4.3: now EC 1.8.1.4 dihydrolipoyl dehydrogenase
EC 1.6.4.4: now EC 1.8.1.8 protein-disulfide reductase
EC 1.6.4.5: now EC 1.8.1.9 thioredoxin-disulfide reductase
EC 1.6.4.6: now EC 1.8.1.10 CoA-glutathione reductase
EC 1.6.4.7: now EC 1.8.1.11 asparagusate reductase
EC 1.6.4.8: now EC 1.8.1.12 trypanothione-disulfide reductase
EC 1.6.4.9: now EC 1.8.1.13 bis-γ-glutamylcystine reductase
EC 1.6.4.10: now EC 1.8.1.14 CoA-disulfide reductase

EC 1.6.5 With a quinone or similar compound as acceptor

EC 1.6.5.1: deleted
EC 1.6.5.2: NAD(P)H dehydrogenase (quinone)
EC 1.6.5.3: now EC 7.1.1.2 NADH:ubiquinone reductase (H⁺-translocating)
EC 1.6.5.4: monodehydroascorbate reductase (NADH)
EC 1.6.5.5: NADPH:quinone reductase
EC 1.6.5.6: p-benzoquinone reductase (NADPH)
EC 1.6.5.7: 2-hydroxy-1,4-benzoquinone reductase
EC 1.6.5.8: Now EC 7.2.1.1, NADH:ubiquinone reductase (Na⁺-transporting)
EC 1.6.5.9: NADH:ubiquinone reductase (non-electrogenic)
EC 1.6.5.10: NADPH dehydrogenase (quinone)
EC 1.6.5.11: Identical to EC 1.6.5.9, NADH:quinone reductase (non-electrogenic) *
EC 1.6.5.12: demethylphylloquinone reductase *

*No Wikipedia article

EC 1.6.6 With a nitrogenous group as acceptor

EC 1.6.6.1: Now EC 1.7.1.1, nitrate reductase (NADH)
EC 1.6.6.2: Now EC 1.7.1.2, nitrate reductase [NAD(P)H]
EC 1.6.6.3: Now EC 1.7.1.3, nitrate reductase (NADPH)
EC 1.6.6.4: Now EC 1.7.1.4, nitrite reductase [NAD(P)H]
EC 1.6.6.5: Now EC 1.7.2.1, nitrite reductase (NO-forming)
EC 1.6.6.6: Now EC 1.7.1.5, hyponitrite reductase
EC 1.6.6.7: Now EC 1.7.1.6, azobenzene reductase
EC 1.6.6.8: Now EC 1.7.1.7, GMP reductase
EC 1.6.6.9: Now known to be catalysed by EC 1.7.2.3, trimethylamine-N-oxide reductase
EC 1.6.6.10: Now EC 1.7.1.9, nitroquinoline-N-oxide reductase]
EC 1.6.6.11: Now EC 1.7.1.10, hydroxylamine reductase (NADH)
EC 1.6.6.12: Now EC 1.7.1.11, 4-(dimethylamino)phenylazoxybenzene reductase
EC 1.6.6.13: Now EC 1.7.1.12, N-hydroxy-2-acetamidofluorene reductase

EC 1.6.7 With an iron–sulfur protein as acceptor (deleted sub-subclass)

EC 1.6.7.1: now EC 1.18.1.2 ferredoxin—NADP⁺ reductase
EC 1.6.7.2: now EC 1.18.1.1 rubredoxin—NAD⁺ reductase
EC 1.6.7.3: now EC 1.18.1.3 ferredoxin—NAD⁺ reductase

EC 1.6.8 With a flavin as acceptor (deleted sub-subclass)

EC 1.6.8.1: Now EC 1.5.1.29 FMN reductase
EC 1.6.8.2: Now EC 1.5.1.30 flavin reductase

EC 1.6.99 With unknown physiological acceptors

EC 1.6.99.1: NADPH dehydrogenase
EC 1.6.99.2: Now EC 1.6.5.2, NAD(P)H dehydrogenase (quinone
EC 1.6.99.3: The activity is covered by EC 7.1.1.2, NADH:ubiquinone reductase (H⁺-translocating)
EC 1.6.99.4: Now EC 1.18.1.2, ferredoxin—NADP⁺ reductase
EC 1.6.99.5: Now EC 1.6.5.11, NADH dehydrogenase (quinone)
EC 1.6.99.6: Now EC 1.6.5.10, NADPH dehydrogenase (quinone)
EC 1.6.99.7: Now EC 1.5.1.34, 6,7-dihydropteridine reductase
EC 1.6.99.8: Deleted
EC 1.6.99.9: Now EC 1.16.1.4, cob(II)alamin reductase
EC 1.6.99.10: included in EC 1.5.1.34, 6,7-dihydropteridine reductase
EC 1.6.99.11: Deleted
EC 1.6.99.12: Now EC 1.16.1.6, cyanocobalamin reductase (cyanide-eliminating)
EC 1.6.99.13: Now EC 1.16.1.7, ferric-chelate reductase

EC 1.7 Acting on other nitrogenous compounds as donors

EC 1.7.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.7.1.1: nitrate reductase (NADH)
EC 1.7.1.2: nitrate reductase (NAD(P)H)
EC 1.7.1.3: nitrate reductase (NADPH)
EC 1.7.1.4: nitrite reductase (NAD(P)H)
EC 1.7.1.5: hyponitrite reductase
EC 1.7.1.6: azobenzene reductase
EC 1.7.1.7: GMP reductase
EC 1.7.1.8: deleted
EC 1.7.1.9: nitroquinoline-N-oxide reductase
EC 1.7.1.10: hydroxylamine reductase (NADH)
EC 1.7.1.11: 4-(dimethylamino)phenylazoxybenzene reductase
EC 1.7.1.12: N-hydroxy-2-acetamidofluorene reductase
EC 1.7.1.13: preQ₁ synthase
EC 1.7.1.14: nitric oxide reductase (NAD(P), nitrous oxide-forming)
EC 1.7.1.15: nitrite reductase (NADH)
EC 1.7.1.16: nitrobenzene nitroreductase
EC 1.7.1.17: FMN-dependent NADH-azoreductase

EC 1.7.2 With a cytochrome as acceptor

EC 1.7.2.1: nitrite reductase (NO-forming)
EC 1.7.2.2: nitrite reductase (cytochrome; ammonia-forming)
EC 1.7.2.3: trimethylamine-N-oxide reductase
EC 1.7.2.4: nitrous-oxide reductase
EC 1.7.2.5: nitric oxide reductase (cytochrome c)
EC 1.7.2.6: hydroxylamine dehydrogenase
EC 1.7.2.7: hydrazine synthase *
EC 1.7.2.8: hydrazine dehydrogenase *

*No Wikipedia article

EC 1.7.3 With oxygen as acceptor

EC 1.7.3.1: nitroalkane oxidase
EC 1.7.3.2: acetylindoxyl oxidase
EC 1.7.3.3: factor-independent urate hydroxylase
EC 1.7.3.4: Now covered by EC 1.7.2.6, hydroxylamine dehydrogenase, and EC 1.7.3.6, hydroxylamine oxidase (cytochrome)
EC 1.7.3.5: 3-aci-nitropropanoate oxidase
EC 1.7.3.6: hydroxylamine oxidase (cytochrome) *

*No Wikipedia article

EC 1.7.5 With a quinone or similar compound as acceptor

EC 1.7.6 With a nitrogenous group as acceptor

EC 1.7.6.1: nitrite dismutase

EC 1.7.7 With an iron–sulfur protein as acceptor

EC 1.7.99 With other acceptors

EC 1.7.99.1: hydroxylamine reductase
EC 1.7.99.2: deleted: reaction may have been due to the combined action of EC 1.7.99.6 nitrous-oxide reductase and EC 1.7.99.7 nitric-oxide reductase
EC 1.7.99.3: Now included with EC 1.7.2.1, nitrite reductase (NO-forming)
EC 1.7.99.4: Now EC 1.7.1.1, nitrate reductase (NADH), EC 1.7.1.2, nitrate reductase [NAD(P)H], EC 1.7.1.3, nitrate reductase (NADPH), EC 1.7.5.1, nitrate reductase (quinone), EC 1.7.7.2, nitrate reductase (ferredoxin) and EC 1.9.6.1, nitrate reductase (cytochrome)
EC 1.7.99.5: Now included with EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.7.99.6: Now EC 1.7.2.4 nitrous-oxide reductase
EC 1.7.99.7: Now EC 1.7.2.5 nitric oxide reductase (cytochrome c)
EC 1.7.99.8: hydroxylamine oxidoreductase
EC 1.7.99.8: Now classified as EC 1.7.2.8, hydrazine dehydrogenase

EC 1.8 Acting on a sulfur group of donors

EC 1.8.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.8.1.1: deleted
EC 1.8.1.2: sulfite reductase (NADPH)
EC 1.8.1.3: hypotaurine dehydrogenase
EC 1.8.1.4: dihydrolipoyl dehydrogenase
EC 1.8.1.5: 2-oxopropyl-CoM reductase (carboxylating)
EC 1.8.1.6: cystine reductase
EC 1.8.1.7: glutathione-disulfide reductase
EC 1.8.1.8: protein-disulfide reductase
EC 1.8.1.9: thioredoxin-disulfide reductase
EC 1.8.1.10: CoA-glutathione reductase
EC 1.8.1.11: asparagusate reductase
EC 1.8.1.12: trypanothione-disulfide reductase
EC 1.8.1.13: bis-γ-glutamylcystine reductase
EC 1.8.1.14: CoA-disulfide reductase
EC 1.8.1.15: mycothione reductase
EC 1.8.1.16: glutathione amide reductase
EC 1.8.1.17: dimethylsulfone reductase
EC 1.8.1.18: NAD(P)H sulfur oxidoreductase (CoA-dependent) *
EC 1.8.1.19: sulfide dehydrogenase *
EC 1.8.1.20: 4,4′-dithiodibutanoate disulfide reductase *
EC 1.8.1.21: dissimilatory dimethyldisulfide reductase *

*No Wikipedia article

EC 1.8.2 With a cytochrome as acceptor

EC 1.8.2.1: sulfite dehydrogenase (cytochrome)
EC 1.8.2.2: thiosulfate dehydrogenase
EC 1.8.2.3: sulfide-cytochrome-c reductase (flavocytochrome c)
EC 1.8.2.4: dimethyl sulfide:cytochrome c₂ reductase *
EC 1.8.2.5: thiosulfate reductase (cytochrome) *
EC 1.8.2.6: S-disulfanyl-L-cysteine oxidoreductase *
EC 1.8.2.7: thiocyanate desulfurase *

*No Wikipedia article

EC 1.8.3 With oxygen as acceptor

EC 1.8.3.1: sulfite oxidase
EC 1.8.3.2: thiol oxidase
EC 1.8.3.3: glutathione oxidase
EC 1.8.3.4: methanethiol oxidase
EC 1.8.3.5: prenylcysteine oxidase
EC 1.8.3.6: farnesylcysteine lyase
EC 1.8.3.7: formylglycine-generating enzyme *

*No Wikipedia article

EC 1.8.4 With a disulfide as acceptor

EC 1.8.4.1: glutathione—homocystine transhydrogenase
EC 1.8.4.2: protein-disulfide reductase (glutathione)
EC 1.8.4.3: glutathione—CoA-glutathione transhydrogenase
EC 1.8.4.4: glutathione—cystine transhydrogenase
EC 1.8.4.5: Now EC 1.8.4.13, L-methionine (S)-S-oxide reductase and EC 1.8.4.14, L-methionine (R)-S-oxide reductase
EC 1.8.4.6: due to EC 1.8.4.11, peptide-methionine (S)-S-oxide reductase
EC 1.8.4.7: enzyme-thiol transhydrogenase (glutathione-disulfide)
EC 1.8.4.8: phosphoadenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.9: adenylyl-sulfate reductase (glutathione)
EC 1.8.4.10: adenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.11: peptide-methionine (S)-S-oxide reductase
EC 1.8.4.12: peptide-methionine (R)-S-oxide reductase
EC 1.8.4.13: L-methionine (S)-S-oxide reductase
EC 1.8.4.14: L-methionine (R)-S-oxide reductase
EC 1.8.4.15: protein dithiol oxidoreductase (disulfide-forming) *
EC 1.8.4.16: thioredoxin:protein disulfide reductase *

*No Wikipedia article

EC 1.8.5 With a quinone or similar compound as acceptor

EC 1.8.5.1: glutathione dehydrogenase (ascorbate)
EC 1.8.5.2: thiosulfate dehydrogenase (quinone)
EC 1.8.5.3: respiratory dimethylsulfoxide reductase
EC 1.8.5.4: bacterial sulfide:quinone reductase
EC 1.8.5.5: thiosulfate reductase (quinone) *
EC 1.8.5.6: sulfite dehydrogenase (quinone) *
EC 1.8.5.7: glutathionyl-hydroquinone reductase *
EC 1.8.5.8: eukaryotic sulfide quinone oxidoreductase *
EC 1.8.5.9: protein dithiol:quinone oxidoreductase DsbB *

*No Wikipedia article

EC 1.8.6 With a nitrogenous group as acceptor (deleted sub-subclass)

EC 1.8.6.1: Now included with EC 2.5.1.18 glutathione transferase

EC 1.8.7 With an iron–sulfur protein as acceptor

EC 1.8.7.1: assimilatory sulfite reductase (ferredoxin)
EC 1.8.7.2: ferredoxin:thioredoxin reductase
EC 1.8.7.3: ferredoxin:CoB-CoM heterodisulfide reductase *

*No Wikipedia article

EC 1.8.98 With other, known, acceptors

EC 1.8.99 With other acceptors

EC 1.8.99.1: Now covered by EC 1.8.1.2, assimilatory sulfite reductase (NADPH) and EC 1.8.7.1, assimilatory sulfite reductase (ferredoxin)
EC 1.8.99.2: adenylyl-sulfate reductase
EC 1.8.99.3: an in vitro artifact of EC 1.8.99.5, dissimilatory sulfite reductase
EC 1.8.99.4: Now EC 1.8.4.8, phosphoadenylyl-sulfate reductase (thioredoxin)
EC 1.8.99.5: dissimilatory sulfite reductase *

*No Wikipedia article

EC 1.9 Acting on a heme group of donors

EC 1.9.3 With oxygen as acceptor

EC 1.9.3.1: Now EC 7.1.1.9, cytochrome-c oxidase
EC 1.9.3.2: Now included with EC 1.7.2.1, nitrite reductase (NO-forming)

EC 1.9.6 With a nitrogenous group as acceptor

EC 1.9.6.1: nitrate reductase (cytochrome)

EC 1.9.98 With other, known, physiological acceptors

EC 1.9.98.1: iron—cytochrome-c reductase

EC 1.9.99 With other acceptors

EC 1.9.99.1: Now EC 1.9.98.1, iron—cytochrome-c reductase

EC 1.10 Acting on diphenols and related substances as donors

EC 1.10.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.10.1.1: trans-acenaphthene-1,2-diol dehydrogenase

EC 1.10.2 With a cytochrome as acceptor

EC 1.10.2.1: The activity is covered by EC 7.2.1.3, ascorbate ferrireductase (transmembrane)
EC 1.10.2.2: Now EC 7.1.1.8, quinol—cytochrome-c reductase

EC 1.10.3 With oxygen as acceptor

EC 1.10.3.1: catechol oxidase
EC 1.10.3.2: laccase
EC 1.10.3.3: L-ascorbate oxidase
EC 1.10.3.4: o-aminophenol oxidase
EC 1.10.3.5: 3-hydroxyanthranilate oxidase
EC 1.10.3.6: rifamycin-B oxidase
EC 1.10.3.7: Now EC 1.21.3.4, sulochrin oxidase [(+)-bisdechlorogeodin-forming]
EC 1.10.3.8: Now EC 1.21.3.5, sulochrin oxidase [(-)-bisdechlorogeodin-forming]
EC 1.10.3.9: photosystem II
EC 1.10.3.10: Now EC 7.1.1.3, ubiquinol oxidase (H⁺-transporting)
EC 1.10.3.11: ubiquinol oxidase (non-electrogenic)
EC 1.10.3.12: Now EC 7.1.1.5, menaquinol oxidase (H⁺-transporting)
EC 1.10.3.13: Now EC 7.1.1.4, caldariellaquinol oxidase (H⁺-transporting)
EC 1.10.3.14: Now EC 7.1.1.7, ubiquinol oxidase (electrogenic, proton-motive force generating)
EC 1.10.3.15: grixazone synthase *
EC 1.10.3.16: dihydrophenazinedicarboxylate synthase *
EC 1.10.3.17: superoxide oxidase *

*No Wikipedia article

EC 1.10.5 With a quinone or related compound as acceptor

EC 1.10.5.1: ribosyldihydronicotinamide dehydrogenase (quinone)

*No Wikipedia article

EC 1.10.9 With a copper protein as acceptor

EC 1.10.9.1: Now EC 7.1.1.6, plastoquinol—plastocyanin reductase

EC 1.10.99 With unknown physiological acceptors

EC 1.10.99.1: Now EC 1.10.9.1 plastoquinol—plastocyanin reductase
EC 1.10.99.2: Now EC 1.10.5.1 ribosyldihydronicotinamide dehydrogenase (quinone)
EC 1.10.99.3: Now EC 1.23.5.1 violaxanthin de-epoxidase

EC 1.11 Acting on a peroxide as acceptor

EC 1.11.1 Peroxidases

EC 1.11.1.1: NADH peroxidase
EC 1.11.1.2: NADPH peroxidase
EC 1.11.1.3: fatty-acid peroxidase
EC 1.11.1.4: Now EC 1.13.11.11 EC 1.13.11.11 tryptophan 2,3-dioxygenase
EC 1.11.1.5: cytochrome-c peroxidase
EC 1.11.1.6: catalase
EC 1.11.1.7: peroxidase
EC 1.11.1.8: iodide peroxidase
EC 1.11.1.9: glutathione peroxidase
EC 1.11.1.10: chloride peroxidase
EC 1.11.1.11: L-ascorbate peroxidase
EC 1.11.1.12: phospholipid-hydroperoxide glutathione peroxidase
EC 1.11.1.13: manganese peroxidase
EC 1.11.1.14: lignin peroxidase
EC 1.11.1.15: Now described by EC 1.11.1.24, thioredoxin-dependent peroxiredoxin; EC 1.11.1.25, glutaredoxin-dependent peroxiredoxin; EC 1.11.1.26, NADH-dependent peroxiredoxin; EC 1.11.1.27, glutathione-dependent peroxiredoxin; EC 1.11.1.28, lipoyl-dependent peroxiredoxin; and EC 1.11.1.29, mycoredoxin-dependent peroxiredoxin
EC 1.11.1.16: versatile peroxidase
EC 1.11.1.17: glutathione amide-dependent peroxidase
EC 1.11.1.18: bromide peroxidase
EC 1.11.1.19: dye decolorizing peroxidase
EC 1.11.1.20: prostamide/prostaglandin F_2α synthase
EC 1.11.1.21: catalase-peroxidase
EC 1.11.1.22: hydroperoxy fatty acid reductase *
EC 1.11.1.23: (S)-2-hydroxypropylphosphonic acid epoxidase *
EC 1.11.1.24: thioredoxin-dependent peroxiredoxin *
EC 1.11.1.25: glutaredoxin-dependent peroxiredoxin *
EC 1.11.1.26: NADH-dependent peroxiredoxin *
EC 1.11.1.27: glutathione-dependent peroxiredoxin *
EC 1.11.1.28: lipoyl-dependent peroxiredoxin *
EC 1.11.1.29: mycoredoxin-dependent peroxiredoxin *

*No Wikipedia article

EC 1.11.2 Peroxygenase

EC 1.11.2.1: unspecific peroxygenase
EC 1.11.2.2: myeloperoxidase
EC 1.11.2.3: plant seed peroxygenase
EC 1.11.2.4: fatty-acid peroxygenase
EC 1.11.2.5: 3-methyl-L-tyrosine peroxygenase *
EC 1.11.2.6: L-tyrosine peroxygenase *

*No Wikipedia article

EC 1.12 Acting on hydrogen as donor

EC 1.12.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.12.1.1: Now EC 1.12.7.2, ferredoxin hydrogenase
EC 1.12.1.2: hydrogen dehydrogenase
EC 1.12.1.3: hydrogen dehydrogenase (NADP⁺)
EC 1.12.1.4: hydrogenase (NAD⁺, ferredoxin)
EC 1.12.1.5: hydrogen dehydrogenase [NAD(P)⁺] *

*No Wikipedia article

EC 1.12.2 With a cytochrome as acceptor

EC 1.12.2.1: cytochrome-c₃ hydrogenase

EC 1.12.5 With a quinone or similar compound as acceptor

EC 1.12.5.1: hydrogen:quinone oxidoreductase

EC 1.12.7 With an iron–sulfur protein as acceptor

EC 1.12.7.1: Now EC 1.12.7.2, ferredoxin hydrogenase
EC 1.12.7.2: ferredoxin hydrogenase

EC 1.12.98 With other known acceptors

EC 1.12.99 With unknown physiological acceptors

EC 1.12.99.1: Now EC 1.12.98.1, coenzyme F₄₂₀ hydrogenase
EC 1.12.99.2: Now shown to be two enzymes, EC 1.12.98.3, Methanosarcina-phenazine hydrogenase and EC 1.8.98.1, CoB—CoM heterodisulfide reductase
EC 1.12.99.3: Now EC 1.12.5.1, hydrogen:quinone oxidoreductase
EC 1.12.99.4: Now EC 1.12.98.2, 5,10-methenyltetrahydromethanopterin hydrogenase
EC 1.12.99.5: Identical to EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
EC 1.12.99.6: hydrogenase (acceptor)

EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

EC 1.13.11 With incorporation of two atoms of oxygen

EC 1.13.11.1: catechol 1,2-dioxygenase
EC 1.13.11.2: catechol 2,3-dioxygenase
EC 1.13.11.3: protocatechuate 3,4-dioxygenase
EC 1.13.11.4: gentisate 1,2-dioxygenase
EC 1.13.11.5: homogentisate 1,2-dioxygenase
EC 1.13.11.6: 3-hydroxyanthranilate 3,4-dioxygenase
EC 1.13.11.7: deleted
EC 1.13.11.8: protocatechuate 4,5-dioxygenase
EC 1.13.11.9: 2,5-dihydroxypyridine 5,6-dioxygenase
EC 1.13.11.10: 7,8-dihydroxykynurenate 8,8a-dioxygenase
EC 1.13.11.11: tryptophan 2,3-dioxygenase
EC 1.13.11.12: linoleate 13S-lipoxygenas
EC 1.13.11.13: The activity is the sum of several enzymatic and spontaneous reactions
EC 1.13.11.14: 2,3-dihydroxybenzoate 3,4-dioxygenase
EC 1.13.11.15: 3,4-dihydroxyphenylacetate 2,3-dioxygenase
EC 1.13.11.16: 3-carboxyethylcatechol 2,3-dioxygenase
EC 1.13.11.17: indole 2,3-dioxygenase
EC 1.13.11.18: persulfide dioxygenase
EC 1.13.11.19: cysteamine dioxygenase
EC 1.13.11.20: cysteine dioxygenase
EC 1.13.11.21: Now EC 1.14.99.36, β-carotene 15,15′-monooxygenase
EC 1.13.11.22: caffeate 3,4-dioxygenase
EC 1.13.11.23: 2,3-dihydroxyindole 2,3-dioxygenase
EC 1.13.11.24: quercetin 2,3-dioxygenase
EC 1.13.11.25: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
EC 1.13.11.26: peptide-tryptophan 2,3-dioxygenase
EC 1.13.11.27: 4-hydroxyphenylpyruvate dioxygenase
EC 1.13.11.28: 2,3-dihydroxybenzoate 2,3-dioxygenase
EC 1.13.11.29: stizolobate synthase
EC 1.13.11.30: stizolobinate synthase
EC 1.13.11.31: arachidonate 12-lipoxygenase
EC 1.13.11.32: Now EC 1.13.12.16, nitronate monooxygenase
EC 1.13.11.33: arachidonate 15-lipoxygenase
EC 1.13.11.34: arachidonate 5-lipoxygenase
EC 1.13.11.35: pyrogallol 1,2-oxygenase
EC 1.13.11.36: chloridazon-catechol dioxygenase
EC 1.13.11.37: hydroxyquinol 1,2-dioxygenase
EC 1.13.11.38: 1-hydroxy-2-naphthoate 1,2-dioxygenase
EC 1.13.11.39: biphenyl-2,3-diol 1,2-dioxygenase
EC 1.13.11.40: arachidonate 8-lipoxygenase
EC 1.13.11.41: 2,4′-dihydroxyacetophenone dioxygenase
EC 1.13.11.42: identical to EC 1.13.11.11, tryptophan 2,3-dioxygenase
EC 1.13.11.43: lignostilbene αβ-dioxygenase
EC 1.13.11.44: Activity is covered by EC 1.13.11.60, linoleate 8R-lipoxygenase and EC 5.4.4.6, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase
EC 1.13.11.45: linoleate 11-lipoxygenase
EC 1.13.11.46: 4-hydroxymandelate synthase
EC 1.13.11.47: 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
EC 1.13.11.48: 3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase
EC 1.13.11.49: chlorite O₂-lyase
EC 1.13.11.50: acetylacetone-cleaving enzyme
EC 1.13.11.51: 9-cis-epoxycarotenoid dioxygenase
EC 1.13.11.52: indoleamine 2,3-dioxygenase
EC 1.13.11.53: acireductone dioxygenase (Ni²⁺-requiring)
EC 1.13.11.54: acireductone dioxygenase [iron(II)-requiring]
EC 1.13.11.55: sulfur oxygenase/reductase
EC 1.13.11.56: 1,2-dihydroxynaphthalene dioxygenase
EC 1.13.11.57: gallate dioxygenase
EC 1.13.11.58: linoleate 9S-lipoxygenase
EC 1.13.11.59: torulene dioxygenase
EC 1.13.11.60: inoleate 8R-lipoxygenase
EC 1.13.11.61: linolenate 9R-lipoxygenase
EC 1.13.11.62: linoleate 10R-lipoxygenase
EC 1.13.11.63: β-carotene 15,15′-dioxygenase
EC 1.13.11.64: 5-nitrosalicylate dioxygenase
EC 1.13.11.65: carotenoid isomerooxygenase
EC 1.13.11.66: hydroquinone 1,2-dioxygenase
EC 1.13.11.67: 8′-apo-β-carotenoid 14′,13′-cleaving dioxygenase
EC 1.13.11.68: 9-cis-β-carotene 9′,10′-cleaving dioxygenase
EC 1.13.11.69: carlactone synthase
EC 1.13.11.70: all-trans-10′-apo-β-carotenal 13,14-cleaving dioxygenase
EC 1.13.11.71: carotenoid-9′,10′-cleaving dioxygenase
EC 1.13.11.72: 2-hydroxyethylphosphonate dioxygenase
EC 1.13.11.73: methylphosphonate synthase
EC 1.13.11.74: 2-aminophenol 1,6-dioxygenase *
EC 1.13.11.75: all-trans-8′-apo-β-carotenal 15,15′-oxygenase *
EC 1.13.11.76: 2-amino-5-chlorophenol 1,6-dioxygenase *
EC 1.13.11.77: oleate 10S-lipoxygenase *
EC 1.13.11.78: 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) *
EC 1.13.11.79: aerobic 5,6-dimethylbenzimidazole synthase *
EC 1.13.11.80: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase *
EC 1.13.11.81: 7,8-dihydroneopterin oxygenase *
EC 1.13.11.82: 8′-apo-carotenoid 13,14-cleaving dioxygenase *
EC 1.13.11.83: 4-hydroxy-3-prenylphenylpyruvate oxygenase *
EC 1.13.11.84: crocetin dialdehyde synthase *
EC 1.13.11.85: exo-cleaving rubber dioxygenase *
EC 1.13.11.86: 5-aminosalicylate 1,2-dioxygenase *
EC 1.13.11.87: endo-cleaving rubber dioxygenase *
EC 1.13.11.88: isoeugenol monooxygenase *
EC 1.13.11.89: (hydroxymethyl)phosphonate dioxygenase *
EC 1.13.11.90: [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming) *
EC 1.13.11.91: 3-mercaptopropionate dioxygenase *
EC 1.13.11.92: fatty acid α-dioxygenase *

*No Wikipedia article

EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)

EC 1.13.12.1: arginine 2-monooxygenase
EC 1.13.12.2: lysine 2-monooxygenase
EC 1.13.12.3: tryptophan 2-monooxygenase
EC 1.13.12.4: lactate 2-monooxygenase
EC 1.13.12.5: Renilla-type luciferase
EC 1.13.12.6: Cypridina-luciferin 2-monooxygenase
EC 1.13.12.7: firefly luciferase
EC 1.13.12.8: Watasenia-luciferin 2-monooxygenase
EC 1.13.12.9: phenylalanine 2-monooxygenase
EC 1.13.12.10: Reaction covered by EC 1.14.13.59, L-lysine 6-monooxygenase (NADPH)
EC n1.13.12.11: The activity is due to EC 1.14.13.8, flavin-containing monooxygenase
EC 1.13.12.12: transferred to EC 1.13.11.67, 8-apo-β-carotenoid 14′,13′-cleaving dioxygenase
EC 1.13.12.13: Oplophorus-luciferin 2-monooxygenase
EC 1.13.12.14: Now EC 1.14.13.122, chlorophyllide-a oxygenase
EC 1.13.12.15: 3,4-dihydroxyphenylalanine oxidative deaminase
EC 1.13.12.16: nitronate monooxygenase
EC 1.13.12.17: dichloroarcyriaflavin A synthase
EC 1.13.12.18: dinoflagellate luciferase
EC 1.13.12.19: 2-oxoglutarate dioxygenase (ethene-forming)
EC 1.13.12.20: noranthrone monooxygenase *
EC 1.13.12.21: tetracenomycin-F1 monooxygenase *
EC 1.13.12.22: deoxynogalonate monooxygenase *
EC 1.13.12.23: 4-hydroxy-3-prenylbenzoate synthase *
EC 1.13.12.24: calcium-regulated photoprotein *

*No Wikipedia article

EC 1.13.99 Miscellaneous

EC 1.13.99.1: inositol oxygenase
EC 1.13.99.2: Now EC 1.14.12.10, benzoate 1,2-dioxygenase
EC 1.13.99.3: tryptophan 2′-dioxygenase
EC 1.13.99.4: Now EC 1.14.12.9, 4-chlorophenylacetate 3,4-dioxygenase
EC 1.13.99.5: now EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase

EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

EC 1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)

EC 1.14.1.1: now EC 1.14.14.1, unspecific monooxygenase
EC 1.14.1.2: now EC 1.14.13.9, kynurenine 3-monooxygenase
EC 1.14.1.3: deleted, covered by EC 1.14.99.7, squalene monooxygenase and EC 5.4.99.7, lanosterol synthase
EC 1.14.1.4: now EC 1.14.99.2, kynurenine 7,8-hydroxylase
EC 1.14.1.5: now EC 1.14.13.5; imidazoleacetate 4-monooxygenase
EC 1.14.1.6: now EC 1.14.15.4, steroid 11β-monooxygenase
EC 1.14.1.7: now EC 1.14.99.9, steroid 17α-monooxygenase
EC 1.14.1.8: now EC 1.14.99.10, steroid 21-monooxygenase
EC 1.14.1.9: deleted
EC 1.14.1.10: now EC 1.14.99.11 estradiol 6β-monooxygenase
EC 1.14.1.11: deleted

EC 1.14.2 With ascorbate as one donor (deleted sub-subclass)

EC 1.14.2.1: now EC 1.14.17.1, dopamine β-monooxygenase
EC 1.14.2.2: now EC 1.13.11.27, 4-hydroxyphenylpyruvate dioxygenase

EC 1.14.3 With reduced pteridine as one donor (deleted sub-subclass)

EC 1.14.3.1: now EC 1.14.16.1, phenylalanine 4-monooxygenase

EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

EC 1.14.11.1: γ-butyrobetaine dioxygenase
EC 1.14.11.2: procollagen-proline dioxygenase
EC 1.14.11.3: pyrimidine-deoxynucleoside 2′-dioxygenase
EC 1.14.11.4: procollagen-lysine 5-dioxygenase
EC 1.14.11.5: Now included with EC 1.14.11.6 thymine dioxygenase
EC 1.14.11.6: thymine dioxygenase
EC 1.14.11.7: procollagen-proline 3-dioxygenase
EC 1.14.11.8: trimethyllysine dioxygenase
EC 1.14.11.9: flavanone 3-dioxygenase
EC 1.14.11.10: pyrimidine-deoxynucleoside 1′-dioxygenase
EC 1.14.11.11: hyoscyamine (6S)-dioxygenase
EC 1.14.11.12: gibberellin-44 dioxygenase
EC 1.14.11.13: gibberellin 2β-dioxygenase
EC 1.14.11.14: Now EC 1.14.20.13, 6β-hydroxyhyoscyamine epoxidase
EC 1.14.11.15: gibberellin 3β-dioxygenase
EC 1.14.11.16: peptide-aspartate β-dioxygenase
EC 1.14.11.17: taurine dioxygenase
EC 1.14.11.18: phytanoyl-CoA dioxygenase
EC 1.14.11.19: Now EC 1.14.20.4, anthocyanidin synthase
EC 1.14.11.20: deacetoxyvindoline 4-hydroxylase
EC 1.14.11.21: clavaminate synthase
EC 1.14.11.22: Now EC 1.14.20.5, flavone synthase
EC 1.14.11.23: Now EC 1.14.20.6, flavonol synthase
EC 1.14.11.24: 2′-deoxymugineic-acid 2′-dioxygenase
EC 1.14.11.25: mugineic-acid 3-dioxygenase
EC 1.14.11.26: deacetoxycephalosporin-C hydroxylase
EC 1.14.11.27: [histone H3]-dimethyl-L-lysine³⁶ demethylase
EC 1.14.11.28: proline 3-hydroxylase
EC 1.14.11.29: hypoxia-inducible factor-proline dioxygenase
EC 1.14.11.30: hypoxia-inducible factor-asparagine dioxygenase
EC 1.14.11.31: thebaine 6-O-demethylase
EC 1.14.11.32: codeine 3-O-demethylase
EC 1.14.11.33: DNA oxidative demethylase
EC 1.14.11.34: Now EC 1.14.20.7, 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)
EC 1.14.11.35: 1-deoxypentalenic acid 11β-hydroxylase
EC 1.14.11.36: pentalenolactone F synthase
EC 1.14.11.36: pentalenolactone F synthase *
EC 1.14.11.37: kanamycin B dioxygenase *
EC 1.14.11.38: verruculogen synthase *
EC 1.14.11.39: L-asparagine hydroxylase *
EC 1.14.11.40: enduracididine β-hydroxylase *
EC 1.14.11.41: L-arginine hydroxylase *
EC 1.14.11.42: tRNA^Phe (7-(3-amino-3-carboxypropyl)wyosine³⁷-C²)-hydroxylase *
EC 1.14.11.43: (S)-dichlorprop dioxygenase (2-oxoglutarate) *
EC 1.14.11.44: (R)-dichlorprop dioxygenase (2-oxoglutarate) *
EC 1.14.11.45: L-isoleucine 4-hydroxylase *
EC 1.14.11.46: 2-aminoethylphosphonate dioxygenase *
EC 1.14.11.47: [50S ribosomal protein L16]-arginine 3-hydroxylase *
EC 1.14.11.48: xanthine dioxygenase *
EC 1.14.11.49: uridine-5′-phosphate dioxygenase *
EC|1.14.11.50: Now EC 1.14.20.8, (–)-deoxypodophyllotoxin synthase
EC 1.14.11.51: DNA N⁶-methyladenine demethylase *
EC 1.14.11.52: validamycin A dioxygenase *
EC 1.14.11.53: mRNA N⁶-methyladenine demethylase *
EC 1.14.11.54: mRNA N¹-methyladenine demethylase *
EC 1.14.11.55: ectoine hydroxylase *
EC 1.14.11.56: L-proline cis-4-hydroxylase *
EC 1.14.11.57: L-proline trans-4-hydroxylase *
EC 1.14.11.58: ornithine lipid ester-linked acyl 2-hydroxylase *
EC 1.14.11.59: 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase *
EC 1.14.11.60: scopoletin 8-hydroxylase *
EC 1.14.11.61: feruloyl-CoA 6-hydroxylase *
EC 1.14.11.62: trans-4-coumaroyl-CoA 2-hydroxylase *
EC 1.14.11.63: peptidyl-lysine (3S)-dioxygenase *
EC 1.14.11.64: glutarate dioxygenase *
EC 1.14.11.65: [histone H3]-dimethyl-L-lysine⁹ demethylase *
EC 1.14.11.66: [histone H3]-trimethylL-lysine⁹ demethylase *
EC 1.14.11.67: [histone H3]-trimethyl-LL-lysine⁴ demethylase *
EC 1.14.11.68: [histone H3]-trimethyl-L-lysine²⁷ demethylase *
EC 1.14.11.69: [histone H3]-trimethyl-L-lysine³⁷ demethylase *
EC 1.14.11.70: 7-deoxycylindrospermopsin hydroxylase *
EC 1.14.11.71: methylphosphonate hydroxylase *
EC 1.14.11.72: [2-(trimethylamino)ethyl]phosphonate dioxygenase *
EC 1.14.11.73: [protein]-arginine 3-hydroxylase *
EC 1.14.11.74: L-isoleucine 3¹-dioxygenase *
EC 1.14.11.75: 3¹-hydroxy-L-isoleucine 4-dioxygenase *
EC 1.14.11.76: L-glutamate 3(R)-hydroxylase *
EC 1.14.11.77: alkyl sulfatase *

EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor

EC 1.14.12.1: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
EC 1.14.12.2: Now EC 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
EC 1.14.12.3: benzene 1,2-dioxygenase
EC 1.14.12.4: EC 1.14.13.242, 3-hydroxy-2-methylpyridinecarboxylate monooxygenase
EC 1.14.12.5: Now EC .14.13.241, 5-pyridoxate monooxygenase
EC 1.14.12.6: Now EC 1.14.13.66, 2-hydroxycyclohexanone 2-monooxygenase
EC 1.14.12.7: phthalate 4,5-dioxygenase
EC 1.14.12.8: 4-sulfobenzoate 3,4-dioxygenase
EC 1.14.12.9: 4-chlorophenylacetate 3,4-dioxygenase
EC 1.14.12.10: benzoate 1,2-dioxygenase
EC 1.14.12.11: toluene dioxygenase
EC 1.14.12.12: naphthalene 1,2-dioxygenase
EC 1.14.12.13: 2-halobenzoate 1,2-dioxygenase
EC 1.14.12.14: 2-aminobenzenesulfonate 2,3-dioxygenase
EC 1.14.12.15: terephthalate 1,2-dioxygenase
EC 1.14.12.16: 2-hydroxyquinoline 5,6-dioxygenase
EC 1.14.12.17: nitric oxide dioxygenase
EC 1.14.12.18: biphenyl 2,3-dioxygenase
EC 1.14.12.19: 3-phenylpropionate dioxygenase
EC 1.14.12.20: Now classified as EC 1.14.15.17, pheophorbide a oxygenase.
EC 1.14.12.21: Now EC 1.14.13.208, benzoyl-CoA 2,3-epoxidase
EC 1.14.12.22: carbazole 1,9a-dioxygenase
EC 1.14.12.23: nitroarene dioxygenase *
EC 1.14.12.24: 2,4-dinitrotoluene dioxygenase *
EC 1.14.12.25: p-cumate 2,3-dioxygenase *
EC 1.14.12.26: chlorobenzene dioxygenase *

*No Wikipedia article

EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

EC 1.14.13.1: salicylate 1-monooxygenase
EC 1.14.13.2: 4-hydroxybenzoate 3-monooxygenase
EC 1.14.13.3: Now EC 1.14.14.9, 4-hydroxyphenylacetate 3-monooxygenase
EC 1.14.13.4: melilotate 3-monooxygenase
EC 1.14.13.5: imidazoleacetate 4-monooxygenase
EC 1.14.13.6: orcinol 2-monooxygenase
EC 1.14.13.7: phenol 2-monooxygenase
EC 1.14.13.8: flavin-containing monooxygenase
EC 1.14.13.9: kynurenine 3-monooxygenase
EC 1.14.13.10: 2,6-dihydroxypyridine 3-monooxygenase
EC 1.14.13.11: Now EC 1.14.14.91, trans-cinnamate 4-monooxygenase
EC 1.14.13.12: Now EC 1.14.14.92, benzoate 4-monooxygenase
EC 1.14.13.13: Now classified as EC 1.14.15.18, calcidiol 1-monooxygenase
EC 1.14.13.14: trans-cinnamate 2-monooxygenase
EC 1.14.13.15: Now EC 1.14.15.15, cholestanetriol 26-monooxygenase
EC 1.14.13.16: cyclopentanone monooxygenase
EC 1.14.13.17: Now EC 1.14.14.23, cholesterol 7α-monooxygenase
EC 1.14.13.18: 4-hydroxyphenylacetate 1-monooxygenase
EC 1.14.13.19: taxifolin 8-monooxygenase
EC 1.14.13.20: 2,4-dichlorophenol 6-monooxygenase
EC 1.14.13.21: Now EC 1.14.14.82, flavonoid 3′-monooxygenase
EC 1.14.13.22: cyclohexanone monooxygenase
EC 1.14.13.23: 3-hydroxybenzoate 4-monooxygenase
EC 1.14.13.24: 3-hydroxybenzoate 6-monooxygenase
EC 1.14.13.25: methane monooxygenase (soluble)
EC 1.14.13.26: Now classified as EC 1.14.18.4, phosphatidylcholine 12-monooxygenase
EC 1.14.13.27: 4-aminobenzoate 1-monooxygenase
EC 1.14.13.28: Now EC 1.14.14.93, 3,9-dihydroxypterocarpan 6a-monooxygenase
EC 1.14.13.29: 4-nitrophenol 2-monooxygenase
EC 1.14.13.30: Now EC 1.14.14.94, leukotriene-B₄ 20-monooxygenase
EC 1.14.13.31: 2-nitrophenol 2-monooxygenase
EC 1.14.13.32: albendazole monooxygenase
EC 1.14.13.33: 4-hydroxybenzoate 3-monooxygenase (NAD(P)H)
EC 1.14.13.34: leukotriene-E₄ 20-monooxygenase
EC 1.14.13.35: anthranilate 3-monooxygenase (deaminating)
EC 1.14.13.36: Now EC 1.14.14.96, 5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase
EC 1.14.13.37: Now EC 1.14.14.97, methyltetrahydroprotoberberine 14-monooxygenase
EC 1.14.13.38: anhydrotetracycline monooxygenase
EC 1.14.13.39: nitric-oxide synthase
EC 1.14.13.40: anthraniloyl-CoA monooxygenase
EC 1.14.13.41: Now EC 1.14.14.36, tyrosine N-monooxygenase
EC 1.14.13.42: The activity is covered by EC 1.14.13.68, 4-hydroxyphenylacetaldehyde oxime monooxygenase
EC 1.14.13.43: questin monooxygenase
EC 1.14.13.44: 2-hydroxybiphenyl 3-monooxygenase
EC 1.14.13.45: Now EC 1.14.18.2, CMP-N-acetylneuraminate monooxygenase
EC 1.14.13.46: (-)-menthol monooxygenase
EC 1.14.13.47: Now EC

[1]

[2]

List of EC numbers (EC 1)

EC 1.1 Acting on the CH-OH group of donors

EC 1.1.1 With Nicotinamide adenine dinucleotide or NADP as acceptor

EC 1.1.2 With a cytochrome as acceptor

EC 1.1.3 With oxygen as acceptor

EC 1.1.4 With a disulfide as acceptor

EC 1.1.5 With a quinone or similar compound as acceptor

EC 1.1.9 With a copper protein as acceptor

EC 1.1.98 With other, known, acceptors

EC 1.1.99 With unknown physiological acceptors

EC 1.2 Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD+ or NADP+ as acceptor

EC 1.2.2 With a cytochrome as acceptor

EC 1.2.3 With oxygen as acceptor

EC 1.2.4 With a disulfide as acceptor

EC 1.2.5 With a quinone or similar compound as acceptor

EC 1.2.7 With an iron–sulfur protein as acceptor

EC 1.2.99: With unknown physiological acceptors

EC 1.3 Acting on the CH-CH group of donors

EC 1.3.1 With NAD+ or NADP+ as acceptor

EC 1.3.2 With a cytochrome as acceptor

EC 1.3.3 With oxygen as acceptor

EC 1.3.5 With a quinone or related compound as acceptor

EC 1.3.7 With an iron–sulfur protein as acceptor

EC 1.3.8 With a flavin as acceptor

EC 1.3.98 With FMN acceptor

EC 1.3.99 With unknown physiological acceptors

EC 1.4 Acting on the CH-NH2 group of donors

EC 1.4.1 With NAD+ or NADP+ as acceptor

EC 1.4.2 With a cytochrome as acceptor

EC 1.4.3 With oxygen as acceptor

EC 1.4.4 With a disulfide as acceptor

EC 1.4.5 With a quinone or other compound as acceptor

EC 1.4.7 With an iron–sulfur protein as acceptor

EC 1.4.9 With a copper protein as acceptor

EC 1.4.98 With tryptophan tryptophylquinone acceptors

EC 1.4.99 With unknown physiological acceptors

EC 1.5 Acting on the CH-NH group of donors

EC 1.5.1 With NAD+ or NADP+ as acceptor

EC 1.5.3 With oxygen as acceptor

EC 1.5.4 With a disulfide as acceptor

EC 1.5.5 With a quinone or similar compound as acceptor

EC 1.5.7 With an iron–sulfur protein as acceptor

EC 1.5.8 With a flavin or flavoprotein as acceptor

EC 1.5.98 With other, known, physiological acceptors

EC 1.5.99 With unknown physiological acceptors

EC 1.6 Acting on NADH or NADPH

EC 1.6.1 With NAD or NADP as acceptor

EC 1.6.2 With a heme protein as acceptor

EC 1.6.3 With oxygen as acceptor

EC 1.6.4 With a disulfide as acceptor (deleted sub-class)

EC 1.6.5 With a quinone or similar compound as acceptor

EC 1.6.6 With a nitrogenous group as acceptor

EC 1.6.7 With an iron–sulfur protein as acceptor (deleted sub-subclass)

EC 1.6.8 With a flavin as acceptor (deleted sub-subclass)

EC 1.6.99 With unknown physiological acceptors

EC 1.7 Acting on other nitrogenous compounds as donors

EC 1.7.1 With NAD+ or NADP+ as acceptor

EC 1.7.2 With a cytochrome as acceptor

EC 1.7.3 With oxygen as acceptor

EC 1.7.5 With a quinone or similar compound as acceptor

EC 1.7.6 With a nitrogenous group as acceptor

EC 1.7.7 With an iron–sulfur protein as acceptor

EC 1.7.99 With other acceptors

EC 1.8 Acting on a sulfur group of donors

EC 1.8.1 With NAD+ or NADP+ as acceptor

EC 1.8.2 With a cytochrome as acceptor

EC 1.8.3 With oxygen as acceptor

EC 1.8.4 With a disulfide as acceptor

EC 1.8.5 With a quinone or similar compound as acceptor

EC 1.8.6 With a nitrogenous group as acceptor (deleted sub-subclass)

EC 1.8.7 With an iron–sulfur protein as acceptor

EC 1.8.98 With other, known, acceptors

EC 1.8.99 With other acceptors

EC 1.9 Acting on a heme group of donors

EC 1.9.3 With oxygen as acceptor

EC 1.9.6 With a nitrogenous group as acceptor

EC 1.9.98 With other, known, physiological acceptors

EC 1.9.99 With other acceptors

EC 1.10 Acting on diphenols and related substances as donors

EC 1.2.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.3.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.4 Acting on the CH-NH₂ group of donors

EC 1.4.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.5.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.7.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.8.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.10.1 With NAD⁺ or NADP⁺ as acceptor

EC 1.12.1 With NAD⁺ or NADP⁺ as acceptor