MTMR12

MTMR12
Identifiers
AliasesMTMR12, 3-PAP, PIP3AP, myotubularin related protein 12
External IDsOMIM: 606501; MGI: 2443034; HomoloGene: 10403; GeneCards: MTMR12; OMA:MTMR12 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001040446
NM_001294343
NM_001294344
NM_019061

NM_172958
NM_001356498

RefSeq (protein)

NP_001035536
NP_001281272
NP_001281273

NP_766546
NP_001343427

Location (UCSC)Chr 5: 32.23 – 32.31 MbChr 15: 12.21 – 12.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myotubularin related protein 12 is a protein that in humans is encoded by the MTMR12 gene.[5]

Function

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Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000150712Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039458Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Myotubularin related protein 12". Retrieved 2017-05-19.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.