Norepinephrine–dopamine releasing agent

A norepinephrine–dopamine releasing agent (NDRA) is a type of drug which induces the release of norepinephrine (and epinephrine) and dopamine in the body and/or brain.

Examples of NDRAs include phenethylamine, tyramine, amphetamine, methamphetamine, lisdexamfetamine, cathinone, methcathinone, phentermine, propylhexedrine, phenmetrazine, pemoline, 4-methylaminorex, and benzylpiperazine.

NDRAs have psychostimulant effects and are used to treat medical conditions like attention-deficit hyperactivity disorder (ADHD), binge eating disorder, obesity, narcolepsy, and for other indications. They are also used to increase motivation and to enhance performance.

A closely related type of drug is a norepinephrine–dopamine reuptake inhibitor (NDRI), for instance methylphenidate.

• Monoamine releasing agent

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