Russell A. Brown
Russell A. Brown, an American physician and computer scientist, is the inventor[1] of the N-localizer[2] technology that enables guidance of stereotactic surgery or radiosurgery using medical images that are obtained via computed tomography (CT),[3] magnetic resonance imaging (MRI),[4] or positron emission tomography (PET).[5]
Brown invented the N-localizer in 1978 when he was a medical student[6] investigating image-guided surgery in the laboratory of his mentor, James A. Nelson, at the University of Utah. A few months later, Brown designed and built the first CT-compatible stereotactic frame in order to test the concept of the N-localizer.[7]
Brown also made contributions to the k-d tree[8] and to the generalized Born model[9] of implicit solvation.
References
[edit]- ^ "System Using Computed Tomography as for Selective Body Treatment". U.S. Patent 4608977. 1986.
- ^ Galloway, RL Jr. (2015). "Introduction and Historical Perspectives on Image-Guided Surgery". In Golby, AJ (ed.). Image-Guided Neurosurgery. Amsterdam: Elsevier. pp. 3–4.
- ^ Thomas DG, Anderson RE, du Boulay GH (1984). "CT-guided stereotactic neurosurgery: experience in 24 cases with a new stereotactic system". Journal of Neurology, Neurosurgery & Psychiatry. 47 (1): 9–16. doi:10.1136/jnnp.47.1.9. PMC 1027634. PMID 6363629.
- ^ Heilbrun MP, Sunderland PM, McDonald PR, Wells TH Jr, Cosman E, Ganz E (1987). "Brown-Roberts-Wells stereotactic frame modifications to accomplish magnetic resonance imaging guidance in three planes". Applied Neurophysiology. 50 (1–6): 143–152. doi:10.1159/000100700. PMID 3329837.
- ^ Maciunas RJ, Kessler RM, Maurer C, Mandava V, Watt G, Smith G (1992). "Positron emission tomography imaging-directed stereotactic neurosurgery". Stereotactic and Functional Neurosurgery. 58 (1–4): 134–140. doi:10.1159/000098986. PMID 1439330.
- ^ Gildenberg, PL; Krauss, JK (2009). "History of Stereotactic Surgery". In Lozano, AM; Gildenberg, PL; Tasker, RR (eds.). Textbook of Stereotactic and Functional Neurosurgery. Berlin: Springer-Verlag. p. 23.
- ^ Mozdy, Michael (2017-08-10). "Inventing the N-Localizer for Stereotactic Neurosurgery: the Story of a Young Researcher in Radiology and Imaging Sciences". Radiology. Retrieved 2024-08-09.
- ^ Brown R (2015). "Building a balanced k-d tree in O(kn log n) time". Journal of Computer Graphics Techniques. 4 (1): 50–68.
- ^ Brown RA, Case DA (2006). "Second derivatives in generalized Born theory". Journal of Computational Chemistry. 27 (14): 1662–1675. doi:10.1002/jcc.20479. PMID 16900491. S2CID 38418374.
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