Sitafloxacin

Sitafloxacin
Clinical data
Routes of; administration	Oral
ATC code	J01MA21 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid;
CAS Number	127254-12-0 ;
PubChem CID	461399;
ChemSpider	405945 ;
UNII	3GJC60U4Q8;
KEGG	D02475 ;
ChEMBL	ChEMBL108821 ;
CompTox Dashboard (EPA)	DTXSID5048847 ;
Chemical and physical data
Formula	C19H18ClF2N3O3
Molar mass	409.82 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES F[C@H]5C[C@H]5N2/C=C(/C(=O)O)C(=O)c1cc(F)c(c(Cl)c12)N4C[C@@H](N)C3(CC3)C4;
	InChI InChI=1S/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1 ; Key:PNUZDKCDAWUEGK-CYZMBNFOSA-N ;
	(what is this?) (verify)

Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic^[1] that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.^{[citation needed]}

References

^ Anderson DL (July 2008). "Sitafloxacin hydrate for bacterial infections". Drugs of Today. 44 (7): 489–501. doi:10.1358/dot.2008.44.7.1219561. PMID 18806900.

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Clinical data

Routes of administration	Oral
ATC code	J01MA21 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
CAS Number	127254-12-0^N
PubChem CID	461399
ChemSpider	405945^Y
UNII	3GJC60U4Q8
KEGG	D02475^N
ChEMBL	ChEMBL108821^Y
CompTox Dashboard (EPA)	DTXSID5048847
Chemical and physical data
Formula	C₁₉H₁₈ClF₂N₃O₃
Molar mass	409.82 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES F[C@H]5C[C@H]5N2/C=C(/C(=O)O)C(=O)c1cc(F)c(c(Cl)c12)N4C[C@@H](N)C3(CC3)C4
InChI InChI=1S/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1^Y Key:PNUZDKCDAWUEGK-CYZMBNFOSA-N^Y
^NY (what is this?) (verify)