AHCTF1
Protein ELYS jest protein koji je kod ljudi kodiran genom AHCTF1 sa hromosoma 1.[5][6]
Aminokiselinska sekvenca
[uredi | uredi izvor]Dužina polipeptidnog lanca je 2.266 aminokiselina, a molekulska 252 498 težina Da.[7]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MRDLRAQVTS | GLLPFPEVTL | QALGEDEITL | ESVLRGKFAA | GKNGLACLAC | ||||
| GPQLEVVNSI | TGERLSAYRF | SGVNEQPPVV | LAVKEFSWQK | RTGLLIGLEE | ||||
| TEGSVLCLYD | LGISKVVKAV | VLPGRVTAIE | PIINHGGASA | STQHLHPSLR | ||||
| WLFGVAAVVT | DVGQILLVDL | CLDDLSCNQN | EVEASDLEVL | TGIPAEVPHI | ||||
| RESVMRQGRH | LCFQLVSPTG | TAVSTLSYIS | RTNQLAVGFS | DGYLALWNMK | ||||
| SMKREYYIQL | ESGQVPVYAV | TFQEPENDPR | NCCYLWAVQS | TQDSEGDVLS | ||||
| LHLLQLAFGN | RKCLASGQIL | YEGLEYCEER | YTLDLTGGMF | PLRGQTSNTK | ||||
| LLGCQSIEKF | RSHGDREEGV | NEALSPDTSV | SVFTWQVNIY | GQGKPSVYLG | ||||
| LFDINRWYHA | QMPDSLRSGE | YLHNCSYFAL | WSLESVVSRT | SPHGILDILV | ||||
| HERSLNRGVP | PSYPPPEQFF | NPSTYNFDAT | CLLNSGVVHL | TCTGFQKETL | ||||
| TFLKKSGPSL | NELIPDGYNR | CLVAGLLSPR | FVDVQPSSLS | QEEQLEAILS | ||||
| AAIQTSSLGL | LTGYIRRWIT | EEQPNSATNL | RFVLEWTWNK | VVLTKEEFDR | ||||
| LCVPLFDGSC | HFMDPQTIQS | IQQCYLLLSN | LNIVLSCFAS | EAREITERGL | ||||
| IDLSNKFVVS | HLICQYAQVV | LWFSHSGLLP | EGIDDSVQLS | RLCYNYPVIQ | ||||
| NYYTSRRQKF | ERLSRGKWNP | DCLMIDGLVS | QLGERIEKLW | KRDEGGTGKY | ||||
| PPASLHAVLD | MYLLDGVTEA | AKHSITIYLL | LDIMYSFPNK | TDTPIESFPT | ||||
| VFAISWGQVK | LIQGFWLIDH | NDYESGLDLL | FHPATAKPLS | WQHSKIIQAF | ||||
| MSQGEHRQAL | RYIQTMKPTV | SSGNDVILHL | TVLLFNRCMV | EAWNFLRQHC | ||||
| NRLNIEELLK | HMYEVCQEMG | LMEDLLKLPF | TDTEQECLVK | FLQSSASVQN | ||||
| HEFLLVHHLQ | RANYVPALKL | NQTLKINVMN | DRDPRLRERS | LARNSILDQY | ||||
| GKILPRVHRK | LAIERAKPYH | LSTSSVFRLV | SRPKPLSAVP | KQVVTGTVLT | ||||
| RSVFINNVLS | KIGEVWASKE | PINSTTPFNS | SKIEEPSPIV | YSLPAPELPE | ||||
| AFFGTPISKA | SQKISRLLDL | VVQPVPRPSQ | CSEFIQQSSM | KSPLYLVSRS | ||||
| LPSSSQLKGS | PQAISRASEL | HLLETPLVVK | KAKSLAMSVT | TSGFSEFTPQ | ||||
| SILRSTLRST | PLASPSPSPG | RSPQRLKETR | ISFVEEDVHP | KWIPGAADDS | ||||
| KLEVFTTPKK | CAVPVETEWL | KSKDRTTSFF | LNSPEKEHQE | MDEGSQSLEK | ||||
| LDVSKGNSSV | SITSDETTLE | YQDAPSPEDL | EETVFTASKP | KSSSTALTTN | ||||
| VTEQTEKDGD | KDVFASEVTP | SDLQKQMGNL | EDAETKDLLV | AAEAFSELNH | ||||
| LSPVQGTEAS | LCAPSVYEGK | IFTQKSKVPV | LDEGLTSVET | YTPAIRANDN | ||||
| KSMADVLGDG | GNSSLTISEG | PIVSERRLNQ | EVALNLKEDH | EVEVGVLKES | ||||
| VDLPEEKLPI | SDSPPDTQEI | HVIEQEKLEA | QDSGEEARNL | SFNELYPSGT | ||||
| LKLQYNFDTI | DQQFCDLADN | KDTAECDIAE | VDGELFVAQS | NFTLILEGEE | ||||
| GEVEPGDFAS | SDVLPKAANT | ATEEKLVCSG | ENDNHGQIAN | LPSAVTSDQK | ||||
| SQKVDTLPYV | PEPIKVAIAE | NLLDVIKDTR | SKEITSDTME | QSIHETIPLV | ||||
| SQNIMCPTKL | VKSAFKTAQE | TSTMTMNVSQ | VDDVVSSKTR | TRGQRIQNVN | ||||
| VKSAQQEASA | DVATPKMPGQ | SVRKKTRKAK | EISEASENIY | SDVRGLSQNQ | ||||
| QIPQNSVTPR | RGRRKKEVNQ | DILENTSSVE | QELQITTGRE | SKRLKSSQLL | ||||
| EPAVEETTKK | EVKVSSVTKR | TPRRIKRSVE | NQESVEIIND | LKVSTVTSPS | ||||
| RMIRKLRSTN | LDASENTGNK | QDDKSSDKQL | RIKHVRRVRG | REVSPSDVRE | ||||
| DSNLESSQLT | VQAEFDMSAI | PRKRGRPRKI | NPSEDVGSKA | VKEERSPKKK | ||||
| EAPSIRRRST | RNTPAKSENV | DVGKPALGKS | ILVPNEELSM | VMSSKKKLTK | ||||
| KTESQSQKRS | LHSVSEERTD | EMTHKETNEQ | EERLLATASF | TKSSRSSRTR | ||||
| SSKAILLPDL | SEPNNEPLFS | PASEVPRKAK | AKKIEVPAQL | KELVSDLSSQ | ||||
| FVISPPALRS | RQKNTSNKNK | LEDELKDDAQ | SVETLGKPKA | KRIRTSKTKQ | ||||
| ASKNTEKESA | WSPPPIEIRL | ISPLASPADG | VKSKPRKTTE | VTGTGLGRNR | ||||
| KKLSSYPKQI | LRRKML |
Također pogledajte
[uredi | uredi izvor]Reference
[uredi | uredi izvor]- ^ a b c GRCh38: Ensembl release 89: ENSG00000153207 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026491 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Nobuhisa I, Taga T (Apr 2002). "Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues". Genes Cells. 7 (4): 435–46. doi:10.1046/j.1365-2443.2002.00529.x. PMID 11952839.
- ^ "Entrez Gene: AHCTF1 AT hook containing transcription factor 1".
- ^ "UniProt, Q8WYP5" (jezik: en.). Pristupljeno 7. 12. 2021.CS1 održavanje: nepoznati jezik (link)
Vanjski linkovi
[uredi | uredi izvor]- Lokacija ljudskog genoma AHCTF1 i stranica sa detaljima o genu AHCTF1 u UCSC Genome Browseru.
Dopunska literatura
[uredi | uredi izvor]- Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17801–6. doi:10.1073/pnas.0608484103. PMC 1635652. PMID 17098863.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
- Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.