2-dehydro-3-deoxygluconokinase
From Wikipedia the free encyclopedia
| 2-dehydro-3-deoxygluconokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 2-Keto-3-deoxygluconate kinase homohexamer, Thermus thermophilus | |||||||||
| Identifiers | |||||||||
| EC no. | 2.7.1.45 | ||||||||
| CAS no. | 9026-54-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) is an enzyme that catalyzes the chemical reaction
- ATP + 2-dehydro-3-deoxy-D-gluconate ADP + 6-phospho-2-dehydro-3-deoxy-D-gluconate
Thus, the two substrates of this enzyme are ATP and 2-dehydro-3-deoxy-D-gluconate, whereas its two products are ADP and 6-phospho-2-dehydro-3-deoxy-D-gluconate.[1]
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase. Other names in common use include 2-keto-3-deoxygluconokinase, 2-keto-3-deoxy-D-gluconic acid kinase, 2-keto-3-deoxygluconokinase (phosphorylating), 2-keto-3-deoxygluconate kinase, and ketodeoxygluconokinase. This enzyme participates in pentose phosphate pathway and pentose and glucuronate interconversions.
Structural studies[edit]
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1WYE.
References[edit]
