3-demethylubiquinone-9 3-O-methyltransferase
From Wikipedia the free encyclopedia
| 3-demethylubiquinone-9 3-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.64 | ||||||||
| CAS no. | 63774-48-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-demethylubiquinone-9 3-O-methyltransferase (EC 2.1.1.64) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 3-demethylubiquinone-9 S-adenosyl-L-homocysteine + ubiquinone-9
Thus, the two substrates of this enzyme are S-adenosyl methionine and 3-demethylubiquinone-9, whereas its two products are S-adenosylhomocysteine and ubiquinone-9.
This enzyme participates in ubiquinone biosynthesis.
Nomenclature[edit]
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1, 4-benzoquinone 3-O-methyltransferase. Other names in common use include 5-demethylubiquinone-9 methyltransferase, OMHMB-methyltransferase, 2-Octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone, methyltransferase, S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-, and 1,4-benzoquinone-O-methyltransferase.
References[edit]
- Houser RM, Olson RE (June 1977). "5-demethylubiquinone-9-methyltransferase from rat liver mitochondria. Characterization, localization, and solubilization". The Journal of Biological Chemistry. 252 (12): 4017–21. PMID 863914.
- Leppik RA, Stroobant P, Shineberg B, Young IG, Gibson F (March 1976). "Membrane-associated reactions in ubiquinone biosynthesis. 2-Octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase". Biochimica et Biophysica Acta (BBA) - General Subjects. 428 (1): 146–56. doi:10.1016/0304-4165(76)90116-1. PMID 769831.
