40S ribosomal protein S11

RPS11
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 5AJ0, 4KZY, 3J7R, 4D61, 4KZX, 4D5L, 4V5Z, 5FLX, 4UJD, 3J7P, 4KZZ, 4UJE, 4UJC
Identifiers
Aliases	RPS11, S11, ribosomal protein S11
External IDs	OMIM: 180471 MGI: 1351329 HomoloGene: 88443 GeneCards: RPS11
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.33 Start 49,496,365 bp[1] End 49,499,708 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 B3 Start 44,771,803 bp[2] End 44,773,863 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence urethra human penis superficial temporal artery nipple caput epididymis canal of the cervix germinal epithelium lymph node thymus Top expressed in ganglionic eminence blastocyst thymus morula zone of skin ileum spleen yolk sac lung esophagus More reference expression data BioGPS n/a
Gene ontology Molecular function rRNA binding structural constituent of ribosome protein binding RNA binding Cellular component cytoplasm cytosol ribosome focal adhesion intracellular anatomical structure nucleolus extracellular exosome nucleoplasm extracellular matrix membrane cytosolic small ribosomal subunit Biological process viral transcription SRP-dependent cotranslational protein targeting to membrane translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein biosynthesis rRNA processing osteoblast differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6205 27207 Ensembl ENSG00000142534 ENSMUSG00000003429 UniProt P62280 P62281 RefSeq (mRNA) NM_001015 NM_013725 RefSeq (protein) NP_001006 NP_038753 Location (UCSC) Chr 19: 49.5 – 49.5 Mb Chr 7: 44.77 – 44.77 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

40S ribosomal protein S11 is a protein that in humans is encoded by the RPS11 gene.^[5][6][7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved in the recognition of termination codons. This gene is co-transcribed with a small nucleolar RNA gene, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[7]

References[edit]

Further reading[edit]

External links[edit]

• Overview of all the structural information available in the PDB for UniProt: P62280 (40S ribosomal protein S11) at the PDBe-KB.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

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