Cu2+-exporting ATPase
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| Cu2+-exporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.3.4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Cu2+-exporting ATPase (EC 3.6.3.4) is an enzyme with systematic name ATP phosphohydrolase (Cu2+-exporting).[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + H2O + Cu2+in ADP + phosphate + Cu2+out
This P-type ATPase undergoes covalent phosphorylation during the transport cycle.
See also[edit]
References[edit]
- ^ Vulpe C, Levinson B, Whitney S, Packman S, Gitschier J (January 1993). "Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase". Nature Genetics. 3 (1): 7–13. doi:10.1038/ng0193-7. PMID 8490659.
- ^ Petrukhin K, Lutsenko S, Chernov I, Ross BM, Kaplan JH, Gilliam TC (September 1994). "Characterization of the Wilson disease gene encoding a P-type copper transporting ATPase: genomic organization, alternative splicing, and structure/function predictions". Human Molecular Genetics. 3 (9): 1647–56. doi:10.1093/hmg/3.9.1647. PMID 7833924.
- ^ Fagan MJ, Saier MH (January 1994). "P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic trees". Journal of Molecular Evolution. 38 (1): 57–99. doi:10.1007/bf00175496. PMID 8151716.
External links[edit]
- Cu2+-exporting+ATPase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
