Dimaprit

Dimaprit
Names
	Preferred IUPAC name 3-(Dimethylamino)propyl carbamimidothioate
	Other names 3-dimethylaminopropyl sulfanylmethanimidamide
Identifiers
CAS Number	65119-89-3 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL12344 ;
ChemSpider	2968 ;
IUPHAR/BPS	1248;
KEGG	C17930 ;
PubChem CID	3077;
UNII	ZZQ699148P ;
CompTox Dashboard (EPA)	DTXSID0037154 ;
	InChI InChI=1S/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8) Key: OLHQOJYVQUNWPL-UHFFFAOYSA-N ; InChI=1/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8) Key: OLHQOJYVQUNWPL-UHFFFAOYAQ;
	SMILES CN(C)CCCSC(=N)N;
Properties
Chemical formula	C6H15N3S
Molar mass	161.2684 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Dimaprit is a histamine analog working as a selective H₂ histamine receptor agonist.^[1]^[2]^[3]

References[edit]

^ Kartzung, Betram G.; Trevor, Anthony J., eds. (2014). Basic and Clinical Pharmacology (13th ed.). New York: McGraw-Hill Education. p. 364. ISBN 978-0071825054.
^ Kohno, S; Ogawa, K; Nabe, T; Yamamura, H; Ohata, K (May 1993). "Dimaprit, a Histamine H₂-agonist, Inhibits Anaphylactic Histamine Release from Mast Cells and the Decreased Release is Restored by Thioperamide (H₃-antagonist), but not by Cimetidine (H₂-antagonist)". Japanese Journal of Pharmacology. 62 (1): 75–9. doi:10.1254/jjp.62.75. PMID 7688057.
^ Nakamura, T; Ueno, Y; Goda, Y; Nakamura, A; Shinjo, K; Nagahisa, A (March 1997). "Efficacy of a Selective Histamine H₂ Receptor Agonist, Dimaprit, in Experimental Models of Endotoxin Shock and Hepatitis in Mice". European Journal of Pharmacology. 322 (1): 83–89. doi:10.1016/S0014-2999(96)00987-9. PMID 9088875.

Names

Preferred IUPAC name 3-(Dimethylamino)propyl carbamimidothioate
Other names 3-dimethylaminopropyl sulfanylmethanimidamide
Identifiers
CAS Number	65119-89-3^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL12344^N
ChemSpider	2968^N
IUPHAR/BPS	1248
KEGG	C17930^N
PubChem CID	3077
UNII	ZZQ699148P^N
CompTox Dashboard (EPA)	DTXSID0037154
InChI InChI=1S/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8)^N Key: OLHQOJYVQUNWPL-UHFFFAOYSA-N^N InChI=1/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8) Key: OLHQOJYVQUNWPL-UHFFFAOYAQ
SMILES CN(C)CCCSC(=N)N
Properties
Chemical formula	C₆H₁₅N₃S
Molar mass	161.2684 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references