HOXC9

HOXC9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LP0, 2MSY
Identifiers
Aliases	HOXC9, HOX3, HOX3B, homeobox C9
External IDs	OMIM: 142971 MGI: 96199 HomoloGene: 130558 GeneCards: HOXC9
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.13 Start 53,994,895 bp[1] End 54,003,337 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 F3|15 58.04 cM Start 102,884,874 bp[2] End 102,893,531 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon gastrocnemius muscle vastus lateralis muscle subcutaneous adipose tissue tibialis anterior muscle popliteal artery tibial nerve skin of abdomen left uterine tube kidney Top expressed in female urethra ankle joint extensor digitorum longus muscle plantaris muscle serosa of urinary bladder quadriceps femoris muscle soleus muscle vastus lateralis muscle tibialis anterior muscle abdominal wall More reference expression data BioGPS More reference expression data
Gene ontology Molecular function sequence-specific DNA binding DNA binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleoplasm aggresome Biological process embryonic skeletal system morphogenesis multicellular organism development regulation of transcription, DNA-templated transcription, DNA-templated anterior/posterior pattern specification embryonic skeletal system development regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3225 15427 Ensembl ENSG00000180806 ENSMUSG00000036139 UniProt P31274 P09633 RefSeq (mRNA) NM_006897 NM_008272 RefSeq (protein) NP_008828 NP_032298 Location (UCSC) Chr 12: 53.99 – 54 Mb Chr 15: 102.88 – 102.89 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Homeobox protein Hox-C9 is a protein that in humans is encoded by the HOXC9 gene.^[5][6]

Function[edit]

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.^[6]

See also[edit]

• Homeobox

References[edit]

Further reading[edit]

External links[edit]

• HOXC9+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Overview of all the structural information available in the PDB for UniProt: P31274 (Homeobox protein Hox-C9) at the PDBe-KB.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

• v
• t
• e