Protein-coding gene in the species Homo sapiens
Potassium channel, subfamily K, member 13 , also known as KCNK13 is a human gene . The protein encoded by this gene, K2P 13.1 is a potassium channel containing two pore-forming P domains.[ 5] [ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000152315 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045404 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C (March 2001). "THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels" . J. Biol. Chem . 276 (10): 7302–11. doi :10.1074/jbc.M008985200 PMID 11060316 . ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (December 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels" . Pharmacol. Rev . 57 (4): 527–40. doi :10.1124/pr.57.4.12 . PMID 16382106 . S2CID 7356601 . Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Fearon IM, Campanucci VA, Brown ST, Hudasek K, o'Kelly IM, Nurse CA (2006). "Acute Hypoxic Regulation of Recombinant THIK-1 Stably Expressed in HEK293 Cells" . The Arterial Chemoreceptors . ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. Vol. 580. pp. 203–8, discussion 351–9 . doi :10.1007/0-387-31311-7_31 . ISBN 978-0-387-31310-8 PMID 16683720 . Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (2001). "Potassium leak channels and the KCNK family of two-P-domain subunits" . Nat. Rev. Neurosci . 2 (3): 175–84. doi :10.1038/35058574 . PMID 11256078 . S2CID 9682396 . Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Theilig F, Goranova I, Hirsch JR, Wieske M, ÜNsal S, Bachmann S, Veh RW, Derst C (2008). "Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney" . Cell. Physiol. Biochem . 21 (1–3): 63–74. doi :10.1159/000113748 PMID 18209473 . Gierten J, Ficker E, Bloehs R, Schlömer K, Kathöfer S, Scholz E, Zitron E, Kiesecker C, Bauer A (2008). "Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein" . Br. J. Pharmacol . 154 (8): 1680–90. doi :10.1038/bjp.2008.213 . PMC 2518462 PMID 18516069 .
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