List of enzymes

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Enzymes are listed here by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission (EC) numbering system:

Category:Oxidoreductases (EC 1) (Oxidoreductase)[edit]

Category:EC 1.1 (act on the CH-OH group of donors)[edit]

Category:EC 1.2 (act on the aldehyde or oxo group of donors)[edit]

Category:EC 1.3 (act on the CH-CH group of donors)[edit]

Category:EC 1.4 (act on the CH-NH2 group of donors)[edit]

Category:EC 1.5 (act on CH-NH group of donors)[edit]

Category:EC 1.6 (act on NADH or NADPH)[edit]

Category:EC 1.7 (act on other nitrogenous compounds as donors)[edit]

Category:EC 1.8 (act on a sulfur group of donors)[edit]

Category:EC 1.9 (act on a heme group of donors)[edit]

Category:EC 1.10 (act on diphenols and related substances as donors)[edit]

Category:EC 1.11 (act on peroxide as an acceptor -- peroxidases)[edit]

Category:EC 1.12 (act on hydrogen as a donor)[edit]

Category:EC 1.13 (act on single donors with incorporation of molecular oxygen)[edit]

Category:EC 1.14 (act on paired donors with incorporation of molecular oxygen)[edit]

Category:EC 1.15 (act on superoxide radicals as acceptors)[edit]

Category:EC 1.16 (oxidize metal ions)[edit]

Category:EC 1.17 (act on CH or CH2 groups)[edit]

Category:EC 1.18 (act on iron–sulfur proteins as donors)[edit]

Category:EC 1.19 (act on reduced flavodoxin as donor)[edit]

Category:EC 1.20 (act on phosphorus or arsenic as donors)[edit]

Category:EC 1.21 (act on X-H and Y-H to form an X-Y bond)[edit]

Category:EC 1.97 (other oxidoreductases)[edit]

Category:Transferases (EC 2) (Transferase)[edit]

Category:EC 2.1 (transfer one-carbon groups, Methylase)[edit]

Category:EC 2.2 (transfer aldehyde or ketone groups)[edit]

Category:EC 2.3 (acyltransferases)[edit]

Category:EC 2.4 (glycosyltransferases)[edit]

Category:EC 2.5

Category:EC 2.5 (transfer alkyl or aryl groups, other than methyl groups)[edit]

Category:EC 2.6 (transfer nitrogenous groups)[edit]

Category:EC 2.7 (transfer phosphorus-containing groups)[edit]

Category:EC 2.8 (transfer sulfur-containing groups)[edit]

Category:EC 2.9 (transfer selenium-containing groups)[edit]

  • EC L-seryl-tRNA(Sec) selenium transferase
  • EC O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase

Category:Hydrolases (EC 3) (Hydrolase)[edit]

Category:EC 3.1 (act on ester bonds)[edit]

Category:EC 3.2 (act on sugars - glycosylases)[edit]

Function and clinical importance of some enzymes in category 3.2.1[edit]


Function: Amylase is an enzyme that is responsible for the breaking of the bonds in starches, polysaccharides, and complex carbohydrates to be turned into simple sugars that will be easier to absorb.

Clinical Significance: Amylase also has medical history in the use of Pancreatic Enzyme Replacement Therapy (PERT). One of the components is Sollpura (liprotamase), which help in the breakdown of saccharides into simple sugars.


Function: An enzyme that is produced by animals that forms part of the innate immune system and is abundant in the secretions of saliva, human milk, tears, and mucus. It functions as an antimicrobial agent by splitting the peptidoglycan component of bacterial cell walls, which then leads to cell death.

Clinical Significance: Toxic levels of blood are caused by the excessive production of lysozyme's by cancer cells. Lysozyme's have also been associated with Bronchopulmonary dysplasia (BPD) in newborns and is a key factor in providing the immunology of infants during breast feeding.


Function: Sucrase is a stomachs related protein that mobilizes hydrolysis to convert sucrose into glucose and fructose.

Clinical Significance: Low amounts of Sucrose also known as Sucrose intolerance happens when sucrose isn't being discharged in the small digestive tract. A result of this is extra gas.


Function: lactase is located in the small digestives system of people and other creatures such as mammals. Lactase is the bases of the total absorption of milk.

Clinical Significance: People who are lactose intolerant have medicine that can help with the digestion. When you are lactose intolerant you might experience gas, bloating, and pain along with other symptoms regarding your digestive system.

Category:EC 3.3 (act on ether bonds)[edit]

Category:EC 3.4 (act on peptide bonds - Peptidase)[edit]

Category:EC 3.5 (act on carbon–nitrogen bonds, other than peptide bonds)[edit]

Category:EC 3.6 (act on acid anhydrides)[edit]

Category:EC 3.7 (act on carbon–carbon bonds)[edit]

Category:EC 3.8 (act on halide bonds)[edit]

Category:EC 3.9 (act on phosphorus–nitrogen bonds)[edit]

Category:EC 3.10 (act on sulfur–nitrogen bonds)[edit]

Category:EC 3.11 (act on carbon–phosphorus bonds)[edit]

Category:EC 3.12 (act on sulfur–sulfur bonds)[edit]

Category:EC 3.13 (act on carbon–sulfur bonds)[edit]

Category:Lyases (EC 4) (Lyase)[edit]

Category:EC 4.1 (carbon–carbon lyases)[edit]

Category:EC 4.2 (carbon–oxygen lyases)[edit]

Category:EC 4.3 (carbon–nitrogen lyases)[edit]

Category:EC 4.4 (carbon–sulfur lyases)[edit]

Category:EC 4.5 (carbon–halide lyases)[edit]

Category:EC 4.6 (phosphorus–oxygen lyases)[edit]

Category:Isomerases (EC 5) (Isomerase)[edit]

Category:EC 5.1 (racemases and epimerases)[edit]

Category:EC 5.2 (cis-trans-isomerases)[edit]

Category:EC 5.3 (intramolecular oxidoreductases)[edit]

Category:EC 5.4 (intramolecular transferases -- mutases)[edit]

Category:EC 5.5 (intramolecular lyases)[edit]

Intramolecular lyases:
EC number Examples
EC Muconate cycloisomerase
EC 3-carboxy-cis,cis-muconate cycloisomerase
EC Tetrahydroxypteridine cycloisomerase
EC Inositol-3-phosphate synthase
EC Carboxy-cis,cis-muconate cyclase
EC Chalcone isomerase
EC Chloromuconate cycloisomerase
EC (+)-bornyl diphosphate synthase
EC Cycloeucalenol cycloisomerase
EC Alpha-pinene-oxide decyclase
EC Dichloromuconate cycloisomerase
EC Copalyl diphosphate synthase
EC Ent-copalyl diphosphate synthase
EC Syn-copalyl-diphosphate synthase
EC Terpentedienyl-diphosphate synthase
EC Halimadienyl-diphosphate synthase
EC (S)-beta-macrocarpene synthase
EC Lycopene epsilon-cyclase
EC Lycopene beta-cyclase
EC Prosolanapyrone-III cycloisomerase
EC 5.5.1.n1 D-ribose pyranase
EC Steroid Delta Isomerase

Category:EC 5.99 (other isomerases)[edit]

Category:Ligases (EC 6) (Ligase)[edit]

Category:EC 6.1 (form carbon–oxygen bonds)[edit]

6-carboxytetrahydropterin synthase

Category:EC 6.2 (form carbon–sulfur bonds)[edit]

Category:EC 6.3 (form carbon–nitrogen bonds)[edit]

Category:EC 6.4 (form carbon–carbon bonds)[edit]

Category:EC 6.5 (form phosphoric ester bonds)[edit]

Category:EC 6.6 (form nitrogen–metal bonds)[edit]

Other list of enzymes[edit]