NCAPH2

NCAPH2
Identifiers
Aliases	NCAPH2, CAPH2, non-SMC condensin II complex subunit H2
External IDs	OMIM: 611230 MGI: 1289164 HomoloGene: 12045 GeneCards: NCAPH2
Gene location (Human)
Chr.	Chromosome 22 (human)
End	50,524,780 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	89,257,029 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; vena cava; ; ganglionic eminence; ; anterior pituitary; ; left uterine tube; ; prefrontal cortex; ; body of pancreas; ; upper lobe of left lung; ; canal of the cervix; ; right lobe of thyroid gland;
	Top expressed in
	spermatocyte; ; lip; ; corneal stroma; ; yolk sac; ; superior frontal gyrus; ; morula; ; spermatid; ; thymus; ; neural tube; ; proximal tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; chromatin binding;
Cellular component	membrane; chromosome; nucleus; nucleoplasm; cell junction; intercellular bridge; condensed chromosome; condensin complex;
Biological process	chromosome condensation; female meiotic nuclear division; meiotic chromosome condensation; T cell differentiation in thymus; chromosome organization; mitotic sister chromatid separation; female meiosis chromosome separation; mitotic chromosome condensation;
	Sources:Amigo / QuickGO
Orthologs
	29781
	52683
	ENSG00000025770
	ENSMUSG00000008690
	Q6IBW4
	Q8BSP2
	NM_001185011; NM_014551; NM_152299
	NM_001115132; NM_001271600; NM_001271601
	NP_001171940; NP_055366; NP_689512
	NP_001108604; NP_001258529; NP_001258530
	Wikidata
View/Edit Human	View/Edit Mouse

Condensin-2 complex subunit H2, also known as chromosome-associated protein H2 (CAP-H2) or non-SMC condensin II complex subunit H2 (NCAPH2), is a protein that in humans is encoded by the NCAPH2 gene.^[5] CAP-H2 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000025770 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000008690 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: non-SMC condensin II complex".

Further reading[edit]

Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
Ono T, Losada A, Hirano M, et al. (2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell. 115 (1): 109–21. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.
Talmud PJ, Drenos F, Shah S, et al. (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
Wood AJ, Severson AF, Meyer BJ (2010). "Condensin and cohesin complexity: the expanding repertoire of functions". Nat. Rev. Genet. 11 (6): 391–404. doi:10.1038/nrg2794. PMC 3491780. PMID 20442714.
Schleiffer A, Kaitna S, Maurer-Stroh S, et al. (2003). "Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners". Mol. Cell. 11 (3): 571–5. doi:10.1016/S1097-2765(03)00108-4. PMID 12667442.
Kamatani Y, Matsuda K, Okada Y, et al. (2010). "Genome-wide association study of hematological and biochemical traits in a Japanese population". Nat. Genet. 42 (3): 210–5. doi:10.1038/ng.531. PMID 20139978. S2CID 30790619.
Collins JE, Wright CL, Edwards CA, et al. (2004). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bailey SD, Xie C, Do R, et al. (2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000025770 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000008690 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: non-SMC condensin II complex".

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NCAPH2

References[edit]

Further reading[edit]

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