Oleoyl-(acyl-carrier-protein) hydrolase
From Wikipedia the free encyclopedia
| acyl-ACP thioesterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.14 | ||||||||
| CAS no. | 68009-83-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) catalyzes the reaction
- an oleoyl-[acyl-carrier-protein] + H2O an [acyl-carrier-protein] + oleate
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is oleoyl-[acyl-carrier-protein] hydrolase. Other names in common use include acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, and oleoyl-acyl carrier protein thioesterase. This enzyme participates in fatty acid biosynthesis.
Structural studies[edit]
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2OWN and 2PFF.
References[edit]
- Ohlrogge JB, Shine WE, Stumpf PK (1978). "Fat metabolism in higher plants. Characterization of plant acyl-ACP and acyl-CoA hydrolases". Arch. Biochem. Biophys. 189 (2): 382–91. doi:10.1016/0003-9861(78)90225-4. PMID 30409.
- Shine WE, Mancha M, Stumpf PK (1976). "Fat metabolism in higher plants. The function of acyl thioesterases in the metabolism of acyl-coenzymes A and acyl-acyl carrier proteins". Arch. Biochem. Biophys. 172 (1): 110–6. doi:10.1016/0003-9861(76)90054-0. PMID 3134.
