Orelabrutinib

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Orelabrutinib
Clinical data
Trade names宜诺凯
Other namesICP-022; ICP022
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 2-(4-Phenoxyphenyl)-6-(1-prop-2-enoylpiperidin-4-yl)pyridine-3-carboxamide
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC26H25N3O3
Molar mass427.504 g·mol−1

Orelabrutinib is a drug for the treatment of cancer.

In China, it is approved for patients with mantle cell lymphoma (MCL) and chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), who have received at least one treatment in the past.[1]

Orelabrutinib is an inhibitor of Bruton's tyrosine kinase.[2]

References[edit]

  1. ^ Dhillon S (March 2021). "Orelabrutinib: First Approval". Drugs. 81 (4): 503–507. doi:10.1007/s40265-021-01482-5. PMID 33704654.
  2. ^ Deng LJ, Zhou KS, Liu LH, Zhang MZ, Li ZM, Ji CY, et al. (August 2023). "Orelabrutinib for the treatment of relapsed or refractory MCL: a phase 1/2, open-label, multicenter, single-arm study". Blood Advances. 7 (16): 4349–4357. doi:10.1182/bloodadvances.2022009168. PMC 10432605. PMID 37078706.