Peptide-transporting ATPase
From Wikipedia the free encyclopedia
| peptide-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.3.43 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a peptide-transporting ATPase (EC 3.6.3.43) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + peptidein ADP + phosphate + peptideout
The 3 substrates of this enzyme are ATP, H2O, and peptide, whereas its 3 products are ADP, phosphate, and peptide.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (peptide-exporting).
References[edit]
- Klein C, Entian KD (1994). "Genes involved in self-protection against the lantibiotic subtilin produced by Bacillus subtilis ATCC 6633". Appl. Environ. Microbiol. 60 (8): 2793–801. PMC 201725. PMID 8085823.
- JJ; Roelse, J; Howard, JC; Butcher, GW; Hämmerling, GJ; Neefjes, JJ (1994). "Selectivity of MHC-encoded peptide transporters from human, mouse and rat". Nature. 367 (6464): 648–51. doi:10.1038/367648a0. PMID 8107849.
- Binet R, Letoffe S, Ghigo JM, Delepelaire P, Wandersman C (1997). "Protein secretion by Gram-negative bacterial ABC exporters-a review". Gene. 192 (1): 7–11. doi:10.1016/S0378-1119(96)00829-3. PMID 9224868.
