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RmYN02 is a bat-derived strain of Severe acute respiratory syndrome–related coronavirus. It was discovered in bat droppings collected between May and October 2019 from sites in Mengla County, Yunnan Province, China. It is the second-closest known relative of SARS-CoV-2, the virus strain that causes COVID-19, sharing 93.3% nucleotide identity at the scale of the complete virus genome. RmYN02 contains an insertion at the S1/S2 cleavage site in the spike protein, similar to SARS-CoV-2, suggesting that such insertion events can occur naturally, which was the subject of a paper sent by scientists from the Wuhan Institute of Virology to Nature.
RmYN02 was collected between May and October, 2019, by the Wuhan Institute of Virology, based on an analysis of 302 feces samples collected from 227 bats were collected from Mengla County, Yunnan Province, China.
- RaTG13, 96.2% similarity to SARS-COV-2
- RacCS203, 91.5% similarity to SARS-COV-2
- Bat SARS-like coronavirus RsSHC014
- Bat SARS-like coronavirus WIV1
- Zhou, Hong; Chen, Xing; Hu, Tao; Li, Juan; Song, Hao; Liu, Yanran; Wang, Peihan; Liu, Di; Yang, Jing; Holmes, Edward C.; Hughes, Alice C. (June 8, 2020). "A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein". Current Biology. 30 (11): 2196–2203.e3. doi:10.1016/j.cub.2020.05.023. ISSN 1879-0445. PMC 7211627. PMID 32416074.
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