Thiomuscimol

Thiomuscimol
Names
	Preferred IUPAC name 5-(Aminomethyl)-1,2-thiazol-3-ol
Identifiers
CAS Number	62020-54-6;
3D model (JSmol)	Interactive image;
ChemSpider	5251;
PubChem CID	5448;
CompTox Dashboard (EPA)	DTXSID00211078 ;
	InChI InChI=1S/C4H6N2OS/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7) Key: QVBUOPGWPXUAHT-UHFFFAOYSA-N;
	SMILES C1=C(SN=C1O)CN;
Properties
Chemical formula	C4H6N2OS
Molar mass	130.17 g·mol−1
Melting point	140 °C (decomp.)
Acidity (pKa)	6.06 ± 0.03, 8.85 ± 0.04 (H2O, 21 °C)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Thiomuscimol is a GABA_A receptor agonist which is structurally related to muscimol.^[2]

References[edit]

^ Lykkeberg, Jytte; Krogsgaard-Larsen, Povl; Garegg, Per J.; Norberg, Thomas; Pilotti, Anne-Marie; Anthonsen, T. (1976). "Structural Analogues of GABA. Synthesis of 5-Aminomethyl-3-isothiazolol (Thiomuscimol)". Acta Chemica Scandinavica. 30b: 781–785. doi:10.3891/acta.chem.scand.30b-0781.
^ Krogsgaard-Larsen, P; Hjeds, H; Curtis, DR; Lodge, D; Johnston, GA (1979). "Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues". Journal of Neurochemistry. 32 (6): 1717–24. doi:10.1111/j.1471-4159.1979.tb02284.x. PMID 448364. S2CID 1393563.

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Names

Preferred IUPAC name 5-(Aminomethyl)-1,2-thiazol-3-ol
Identifiers
CAS Number	62020-54-6
3D model (JSmol)	Interactive image
ChemSpider	5251
PubChem CID	5448
CompTox Dashboard (EPA)	DTXSID00211078
InChI InChI=1S/C4H6N2OS/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7) Key: QVBUOPGWPXUAHT-UHFFFAOYSA-N
SMILES C1=C(SN=C1O)CN
Properties
Chemical formula	C₄H₆N₂OS
Molar mass	130.17 g·mol⁻¹
Melting point	140 °C (decomp.)^[1]
Acidity (pK_a)	6.06 ± 0.03, 8.85 ± 0.04 (H₂O, 21 °C)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references