Stein Institute for Research on Aging

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Stein Institute for Research on Aging
Established1983
DirectorAlison A. Moore, MD, MPH, FACP, AGSF
Faculty150
Address9500 Gilman Drive 0664
Location
La Jolla
,
California
Websitehttp://www.aging.ucsd.edu
Stein Clinical Research Building where the Institute is housed

The Sam and Rose Stein Institute for Research on Aging (or simply the Stein Institute for Research on Aging) is a non-profit, multidisciplinary research institute at the University of California, San Diego School of Medicine located in La Jolla, California. Established in 1983, it researches healthy aging through the development and application of the latest advances in biomedical and behavioral sciences.[1]

The more than 150 scientists at the Stein Institute are investigating predictors and associations of successful cognitive and emotional aging. Understanding these processes requires contributions from basic sciences like neurobiology and genetics, along with the input from clinical medicine and social sciences, such as medical anthropology.

History

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The focus of the Stein Institute's research has shifted over the years since its inception in 1983. In the beginning, the primary emphasis was on Alzheimer's disease. Later, this scope was broadened to include various age-related disorders such as cancer and arthritis. Dilip V. Jeste, taking over as director in 2004 set the Institute's main focus on successful aging.[2][3]

Alison A. Moore, MD, MPH, FACP, AGSF, became Director in 2024 with research efforts in geroscience, or the study of factors that drive aging and differences in trajectories of health.

Activities

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Over the past 25 years, the Stein Institute has brought together many scientists,[4] encouraged and funded research published in top scientific journals (such as JAMA),[5][6][7] supported the education of students, including medical students participating in the National Institute on Aging funded MSTAR program [1][8] and presented and broadcast about 300 public lectures on aging as part of its community outreach.[9] The number of views and downloads of the Stein lectures from UCSD-TV and UCTV, as well as YouTube and iTunes has exceeded 1.2 million views in the last couple of years.[10] The Institute's work has been cited in the media, including the BBC, New York Times, NPR, U.S. News & World Report, Huffington Post, USA Today, London Times, and Scientific American, among others.[11][12][13][14]

Successful Aging Evaluation (SAGE) Study

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Stein Institute has developed the UCSD Successful Aging Evaluation (SAGE) Study - a unique cohort of 1,300 randomly selected people in the San Diego country, ranging in age from 50 to 99, with an oversampling of those over age 80. This longitudinal study focuses on the cognitive and emotional aspects of successful aging, including genetic information about various aspects of aging.[15][16][17][18]

Directors

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References

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  1. ^ "USAging". www.usaging.org. Retrieved 2023-08-08.
  2. ^ "UCSD's Stein Institute for Research on Aging Celebrates 20 Years of Exploration Into Aging Diseases". 2003. Archived from the original on 2006-09-01. Retrieved 2012-03-13.
  3. ^ "American Psychiatric Association". 2012. Archived from the original on 2012-01-20. Retrieved 2012-03-13.
  4. ^ "UC San Diego Center for Healthy Aging". Archived from the original on 2012-03-06. Retrieved 2012-03-13.
  5. ^ Meeks, T. W.; Jeste, D. V. (2009). "Neurobiology of Wisdom: A Literature Overview". Archives of General Psychiatry. 66 (4): 355–65. doi:10.1001/archgenpsychiatry.2009.8. PMC 3698847. PMID 19349305.
  6. ^ Jeste, D. V.; Harris, J. C. (2010). "Wisdom--A Neuroscience Perspective". JAMA: The Journal of the American Medical Association. 304 (14): 1602–3. doi:10.1001/jama.2010.1458. PMID 20940386.
  7. ^ "UC San Diego Center for Healthy Aging". Archived from the original on 2012-03-20. Retrieved 2012-03-13.
  8. ^ Jeste, Dilip V.; Halpain, Maureen C.; Trinidad, Geraldine I.; Reichstadt, Jennifer L.; Lebowitz, Barry D. (2007). "UCSD's short-term research training programs for trainees at different levels of career development". Academic Psychiatry: The Journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry. 31 (2): 160–167. doi:10.1176/appi.ap.31.2.160. ISSN 1042-9670. PMID 17344459.
  9. ^ "Stein Institute for Research on Aging -". Archived from the original on 2012-03-11. Retrieved 2012-03-13.
  10. ^ "UC San Diego Center for Healthy Aging". Archived from the original on 2012-03-20. Retrieved 2012-03-13.
  11. ^ Tarkan, Laurie (2008-06-24). "Doctors Say Medication Is Overused in Dementia". The New York Times. Archived from the original on 2018-02-15. Retrieved 2017-02-23.
  12. ^ "Is wisdom in the brain?". Scientific American. Archived from the original on 2012-10-19. Retrieved 2012-03-13.
  13. ^ "11 'Bad' Things We Learned May Actually Be Good For You In 2011". Huffington Post. 2011-12-12. Archived from the original on 2012-02-29. Retrieved 2012-03-13.
  14. ^ Akitunde, Anthonia (2012-11-28). "Antipsychotic Drugs: 4 Commonly Used Meds Aren't Effective Or Safe For Older Adults, New Study Finds". The Huffington Post. Archived from the original on 2012-12-02. Retrieved 2012-11-28.
  15. ^ "With Wisdom Comes Successful Aging". University of Southern California. 2012. Archived from the original on 2012-03-02. Retrieved 2012-03-13.
  16. ^ "UC San Diego Center for Healthy Aging". Archived from the original on 2012-03-06. Retrieved 2012-03-13.
  17. ^ "NBC News - Breaking News & Top Stories - Latest World, US & Local News". Archived from the original on 2012-12-11. Retrieved 2012-12-11.
  18. ^ "American Journal of Psychiatry publishes results from Successful Aging Evaluation study". 9 December 2012. Archived from the original on 7 February 2013. Retrieved 11 December 2012.
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32°52′33″N 117°14′02″W / 32.87583°N 117.23389°W / 32.87583; -117.23389

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