| Saison | 1er tour | 16e de finale | 8e de finale | Quart de finale | Demi-finale | Finale / (Vainqueur) |
| 1994/1995 | | Le Havre AC 1-0 LOSC Lille | | | | (PSG) |
| 1995/1996 | | LOSC Lille 4-1 SM Caen | FC Metz 2-0 LOSC Lille | | | (FC Metz) |
| 1996/1997 | | Sporting Toulon 2-1 LOSC Lille | | | | (RC Strasbourg) |
| 1997/1998 | LOSC Lille 2-2 SM Caen
(t.a.b. 3-2) | Le Mans UC 1-0 LOSC Lille | | | | (PSG) |
| 1998/1999 | Louhans-Cuiseaux 1-0 LOSC Lille | | | | | (Lens) |
| 1999/2000 | LOSC Lille 2-2 Red Star
(t.a.b. 1-4) | | | | | (FC Gueugnon) |
| 2000/2001 | | Girondins de Bordeaux 1-0 LOSC Lille | | | | (Olympique lyonnais) |
| 2001/2002 | | LOSC Lille 0-2 AS Nancy-Lorraine | | | | (Girondins de Bordeaux) |
| 2002/2003 | | FC Istres 1-2 LOSC Lille | LOSC Lille 0-0 Nîmes Olympique
(t.a.b. 3-1) | FC Sochaux-Montbéliard 1-0 a.p LOSC Lille | | (AS Monaco) |
| 2003/2004 | | Nîmes 1-2 LOSC Lille | LOSC Lille 2-3 AS Saint-Étienne | | | (FC Sochaux-Montbéliard) |
| 2004/2005 | | LOSC Lille 3-2 a.p Olympique lyonnais | RC Strasbourg 1-1 a.p LOSC Lille
(t.a.b. 4-2) | | | (RC Strasbourg) |
| 2005/2006 | | AS Saint-Étienne 0-2 LOSC Lille | AS Monaco 1-0 LOSC Lille | | | (AS Nancy-Lorraine) |
| 2006/2007 | | FC Istres 0-1 LOSC Lille | LOSC Lille 0-1 a.p Stade rennais | | | (Girondins de Bordeaux) |
| 2007/2008 | | RC Lens 1-0 LOSC Lille | | | | (PSG) |
| 2008/2009 | | Montpellier HSC 2-2 LOSC Lille
(t.a.b. 4-2) | | | | (Girondins de Bordeaux) |
| 2009/2010 | | Exempté | LOSC Lille 3-1 (ap) Stade rennais
| Olympique de Marseille 2-1 LOSC Lille
| | (Olympique de Marseille) |
| 2010/2011 | | Exempté | LOSC Lille 4-1 SM Caen
| Montpellier HSC 2-1 LOSC Lille
| | (Olympique de Marseille) |
| 2011/2012 | | Exempté | LOSC Lille 3-1 CS Sedan | Olympique lyonnais 2-1 LOSC Lille | | (Olympique de Marseille) |
| 2012/2013 | | Exempté | LOSC Lille 1-0 Toulouse FC | SC Bastia 0-3 LOSC Lille | AS Saint-Étienne 0-0 LOSC Lille
(t.a.b. 7-6) | (AS Saint-Étienne) |
| 2013/2014 | | LOSC Lille 0-1 (ap) AJ Auxerre | | | | (PSG) |
| 2014/2015 | | Exempté | LOSC Lille 1-1 Girondins de Bordeaux (t.a.b 6-5) | LOSC Lille 2-0 FC Nantes | LOSC Lille 0-1 PSG | (PSG) |
| 2015/2016 | | LOSC Lille 2-1 ESTAC Troyes | LOSC Lille 1-0 Stade lavallois | En Avant de Guingamp 0-0 LOSC Lille
(t.a.b. 2-4) | LOSC Lille 5-1 Girondins de Bordeaux | (PSG) |
| 2016/2017 | | Exempté | PSG 3-1 LOSC Lille | | | (PSG) |
| 2017/2018 | | LOSC Lille 2-2 Valenciennes FC
t.a.b. (5-4) | LOSC Lille 1-1 OGC Nice
t.a.b. (2-3) | | | (PSG) |
| 2018/2019 | | RC Strasbourg 2-0 LOSC Lille
| | | | (RC Strasbourg) |
| 2019/2020 | | Exempté | AS Monaco 0-3 LOSC Lille | LOSC Lille 2-0 Amiens SC | Olympique lyonnais 2-2 LOSC Lille
t.a.b. (4-3) | (PSG) |
