BET1

BET1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesBET1, HBet1 golgi vesicular membrane trafficking protein
External IDsOMIM: 605456; MGI: 1343104; HomoloGene: 38108; GeneCards: BET1; OMA:BET1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005868
NM_001317739

NM_009748

RefSeq (protein)

NP_001304668
NP_005859

NP_033878

Location (UCSC)Chr 7: 93.96 – 94 MbChr 6: 4.08 – 4.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BET1 homolog is a protein that in humans is encoded by the BET1 gene.[5][6][7]

This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105829Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032757Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhang T, Wong SH, Tang BL, Xu Y, Peter F, Subramaniam VN, Hong W (Dec 1997). "The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus". J Cell Biol. 139 (5): 1157–68. doi:10.1083/jcb.139.5.1157. PMC 2140212. PMID 9382863.
  6. ^ Waters MG, Pfeffer SR (Nov 1999). "Membrane tethering in intracellular transport". Curr Opin Cell Biol. 11 (4): 453–9. doi:10.1016/S0955-0674(99)80065-9. PMID 10449330.
  7. ^ a b "Entrez Gene: BET1 BET1 homolog (S. cerevisiae)".

Further reading

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