| Isolate | Bark source | Researched activity |
| Paclitaxel, taxanes | Taxus | chemotherapeutic |
| Paeonol | Paeonia suffruticosa[1] | various |
| Honokiol, 4-O-methylhonokiol, magnolol, obovatol | Magnolia | neurotrophic & anti-inflammatory |
| Salicylic acid | Salix alba | antipyretic, analgesic |
| Yohimbine, corynanthine, ajmalicine, rauwolscine | west African evergreen | MAOI, stimulant |
| beta-carbolines, harmala alkaloids | numerous | MAOI |
| Cinnamon, camphor, cinnamaldehyde | Cinnamomum | blood sugar stabilizer, antioxidant |
| Quinine, quinidine, cinchonidine, cinchonine | Cinchona | antipyretic, analgesic, antimalarial |
| Safrole | Sassafras | |
| Huáng bǎi | Amur cork tree (Phellodendron amurense) | TCM |
| Strictamine | Alstonia scholaris | |
| | Slippery Elm (Ulmus rubra) | demulcent |
| Geniposidic acid | Eucommia ulmoides | |
| N-methyltryptamine, serotonin analogs | numerous species from Brazil, Mexico, Taiwan | serotonin agonist, neuroimmunologic modulator |
| Quassin | Quassia amara | various |
| Celastrol | Tripterygium wilfordii[2] | various |
| Mitraphylline | Cat's claw (Uncaria tomentosa) | anti-inflammatory |
| Ellagic acid, rutin, gallic acid, ethyl gallate[3] | Ailanthus altissima | various |
| Coronaridine, voacangine, ibogamine, ibogaine, tabernanthine | Voacanga africana, Tabernanthe iboga | neuroimmunologic modulator |
| Lapachol, quercetin | Pau D'Arco (Handroanthus impetiginosus) | therapeutic naphthoquinone |
| Icariin | Eucommia | PDE5 inhibitor |
| Baicalin | Oroxylum indicum | prolyl endopeptidase inhibitor |
| Frankincense, incensole | Boswellia sacra, Boswellia | incensole is a TRPV3 agonist |
| QS21 | Quillaja saponaria (soap bark tree) | potential immunologic adjuvant |
| Sandalwood oil, α-Santalol, β-Santalol | Sandalwood (Santalum) | Ayurvedic component |
| Bergenin, α-viniferin, ε-viniferin, diptoindonesin A | Bergenia ligulata, Dryobalanops aromatica, Mallotus japonicus | component of Ayurvedic medicine "Paashaanbhed" |
| Phenolic lactones | Caesalpinia paraguariensis | component of Bolivian traditional medicine |
| Erythravine | Erythrina mulungu | Brazilian medicinal plant |
| Antimicrobial, anti-inflammatory compounds | Psidium guajava (Guava tree) | component of traditional medicine |
| Perfume resin | Agarwood / Oud Wood | aromatherapy |
| Opopanax, balsam, bdellium, bisabol | Myrrh (Commiphora) | component of Eastern-Mediterranean, Middle-Eastern, and North-African, traditional medicine |
| Rotenoids, piscidone | Jamaican dogwood (Piscidia piscipula) | component of Caribbean traditional medicine |
