Chlorbenzoxamine

Chlorbenzoxamine
Clinical data
ATC code	A03AX03 (WHO) ;
Identifiers
	IUPAC name 1-(2-[(2-chlorophenyl)(phenyl)methoxy]ethyl)-4-(2-methylbenzyl)piperazine;
CAS Number	522-18-9;
PubChem CID	71636;
ChemSpider	64700;
UNII	N52918SLYN;
KEGG	D07093;
ChEMBL	ChEMBL2110781;
CompTox Dashboard (EPA)	DTXSID80862108 ;
ECHA InfoCard	100.007.568
Chemical and physical data
Formula	C27H31ClN2O
Molar mass	435.01 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc1ccccc1C(OCCN2CCN(CC2)Cc3ccccc3C)c4ccccc4;

Chlorbenzoxamine is a drug used for functional gastrointestinal disorders.

Synthesis

References

^ Morren HG, Denayer R, Linz R, Strubbe H, Trolin S (1957). "Carbinoxamine". Ind. Chim. Belg. 22: 429.
^ GB 837986, Morren, Henri, "New piperazine derivatives and process for the preparation thereof", published 1960-06-22

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[1] Morren HG, Denayer R, Linz R, Strubbe H, Trolin S (1957). "Carbinoxamine". Ind. Chim. Belg. 22: 429.

[2] GB 837986, Morren, Henri, "New piperazine derivatives and process for the preparation thereof", published 1960-06-22

[1]

[2]

v t e Piperazines
Simple piperazines (no additional rings)	Aminoethylpiperazine Diethylcarbamazine HEPPS Midafotel Piperazine PIPES
Phenylpiperazines	2C-B-PP 3,4-CFP Acaprazine Antrafenine Aripiprazole Batoprazine Bifeprunox BRL-15,572 Ciprofloxacin CSP-2503 Dapiprazole DCPP DMPP Diphenylpiperazine Dropropizine EGIS-12,233 Elopiprazole Eltoprazine Enpiprazole Ensaculin Etoperidone Flesinoxan Fluanisone Flibanserin Fluprazine Itraconazole Ketoconazole Levodropropizine Lorpiprazole mCPP Mefway MeOPP Mepiprazole Naftopidil Naluzotan Naphthylpiperazine Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885 Sonepiprazole TFMPP Tolpiprazole Trazodone Urapidil Vesnarinone Vilazodone Vortioxetine WAY-100,135 WAY-100,635
Benzylpiperazines	2C-B-BZP 3-Methylbenzylpiperazine Befuraline Bifeprunox Buclizine BZP Chlorbenzoxamine DBZP Fipexide Imatinib MBZP MDBZP Meclozine Methoxypiperamide NSI-189 Piberaline Piribedil RN-1747 Sunifiram Trimetazidine Vesnarinone
Diphenylalkylpiperazines (benzhydrylalkylpiperazines)	AD-1211 Almitrine Amperozide BRL-15,572 Buclizine BW373U86 Cetirizine Chlorbenzoxamine Chlorcyclizine Cinnarizine Clocinizine Cyclizine DBL-583 Diphenpipenol Diphenylmethylpiperazine Dotarizine DPI-221 DPI-287 DPI-3290 GBR-12,783 GBR-12,935 GBR-13,069 GBR-13,098 GBR-13,119 Hydroxyzine JJC8-088 Lidoflazine Manidipine Meclozine MT-45 Oxatomide SNC-80 Vanoxerine
Pyrimidinylpiperazines	Buspirone Dasatinib Eptapirone Gepirone Ipsapirone Piribedil Pyrimidinylpiperazine Revospirone Tandospirone Tirilazad Trimazosin Umespirone Zalospirone
Pyridinylpiperazines	Atevirdine Azaperone Delavirdine Mirtazapine ORG-12962 Pyridinylpiperazine
Benzo(iso)thiazolyl piperazines	Lurasidone Perospirone Revospirone Tiospirone Ziprasidone
Tricyclics (piperazine attached via side chain)	Amoxapine Clopenthixol Clorotepine Clozapine Cyanothepin Doclothepin Docloxythepin Flupentixol Fluphenazine Isofloxythepin Loxapine Meperathiepin Metitepine Octomethothepin Olanzapine Opipramol Oxyclothepin Oxyprothepin Peradithiepin Perathiepin Perazine Perphenazine Pirenzepine Prochlorperazine Thiethylperazine Thiothixene Trifluoperazine Trifluthepin Zuclopenthixol
Others/Uncategorized	6-Nitroquipazine AP-238 Azimilide Bucinnazine Cinepazet Cinepazic acid Cinepazide CPD-1 Cyclohexylpiperazine EGIS-7625 Hexocyclium Indinavir JNJ-7777120 Lodenafil MK-212 Mirodenafil PB-28 Quipazine Ranolazine SA-4503 Sildenafil Tadalafil Vardenafil VUF-6002 WY-46824 Zipeprol

Clinical data

ATC code	A03AX03 (WHO)
Identifiers
IUPAC name 1-(2-[(2-chlorophenyl)(phenyl)methoxy]ethyl)-4-(2-methylbenzyl)piperazine
CAS Number	522-18-9
PubChem CID	71636
ChemSpider	64700
UNII	N52918SLYN
KEGG	D07093
ChEMBL	ChEMBL2110781
CompTox Dashboard (EPA)	DTXSID80862108
ECHA InfoCard	100.007.568
Chemical and physical data
Formula	C₂₇H₃₁ClN₂O
Molar mass	435.01 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc1ccccc1C(OCCN2CCN(CC2)Cc3ccccc3C)c4ccccc4

Chlorbenzoxamine

Synthesis

See also

References

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