Doliracetam

Doliracetam
Clinical data
ATC code	none;
Legal status
Legal status	In general: unscheduled;
Identifiers
	IUPAC name 2-(2-oxo-3-phenyl-3H-indol-1-yl)acetamide;
CAS Number	84901-45-1 ;
PubChem CID	208851;
ChemSpider	180958 ;
UNII	N70177JQTB;
ChEMBL	ChEMBL2106519 ;
CompTox Dashboard (EPA)	DTXSID20868846 ;
Chemical and physical data
Formula	C16H14N2O2
Molar mass	266.300 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1=CC=C(C=C1)C2C3=CC=CC=C3N(C2=O)CC(=O)N;
	InChI InChI=1S/C16H14N2O2/c17-14(19)10-18-13-9-5-4-8-12(13)15(16(18)20)11-6-2-1-3-7-11/h1-9,15H,10H2,(H2,17,19) ; Key:MVZYGLQQNPFARE-UHFFFAOYSA-N ;
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Doliracetam is a nootropic drug (cognition enhancer) from the racetam family used in treatment of epilepsy.^[1]^[2]

According to the Hoechst patent title, it has neuroanabolic action.

References

^ EP 62887, Kuch, Heinz & Kruse, Hansjörg, "Indolinone-2 derivatives, process for their preparation and neuro-anabolic mediums containing them", published 1982-10-20, assigned to Hoechst AG
^ Fariello RG, Ghelardini C, Di Cesare Mannelli L, Bonanno G, Pittaluga A, Milanese M, Misiano P, Farina C (June 2014). "Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain". Neuropharmacology. 81: 85–94. doi:10.1016/j.neuropharm.2014.01.029. PMID 24486381. S2CID 28039482.

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v t e Racetams
Racetams	Nootropics: Aniracetam Coluracetam Dimiracetam Doliracetam Dupracetam Fasoracetam Imuracetam Nebracetam Nefiracetam Nicoracetam Oxiracetam Piperacetam Piracetam Pramiracetam Rolipram Rolziracetam Anticonvulsants: Brivaracetam Etiracetam Levetiracetam Seletracetam
Phenylpiracetams	Nootropics and/or stimulants: Cebaracetam Methylphenylpiracetam E1R ((4R,5S)-methylphenylpiracetam) Phenylpiracetam (phenotropil; fonturacetam) MRZ-9547 ((R)-phenylpiracetam) (S)-Phenylpiracetam RGPU-95 (chlorophenylpiracetam) Anticonvulsants: Phenylpiracetam hydrazide
Racetam-like	Nootropics: Aloracetam Molracetam Omberacetam (Noopept) Tenilsetam Traneurocin (cycloprolylglycine; NA-831) Anticonvulsants: Padsevonil

Clinical data

ATC code	none
Legal status
Legal status	In general: unscheduled
Identifiers
IUPAC name 2-(2-oxo-3-phenyl-3H-indol-1-yl)acetamide
CAS Number	84901-45-1^Y
PubChem CID	208851
ChemSpider	180958^N
UNII	N70177JQTB
ChEMBL	ChEMBL2106519^N
CompTox Dashboard (EPA)	DTXSID20868846
Chemical and physical data
Formula	C₁₆H₁₄N₂O₂
Molar mass	266.300 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1=CC=C(C=C1)C2C3=CC=CC=C3N(C2=O)CC(=O)N
InChI InChI=1S/C16H14N2O2/c17-14(19)10-18-13-9-5-4-8-12(13)15(16(18)20)11-6-2-1-3-7-11/h1-9,15H,10H2,(H2,17,19)^N Key:MVZYGLQQNPFARE-UHFFFAOYSA-N^N
^NY (what is this?) (verify)