Lanthanum carbonate
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| Names | |
|---|---|
| IUPAC name Lanthanum carbonate | |
| Other names Fosrenol | |
| Identifiers | |
3D model (JSmol) | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.008.728 |
| EC Number |
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| KEGG | |
PubChem CID | |
| UNII | |
CompTox Dashboard (EPA) | |
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| Properties | |
| La2(CO3)3 | |
| Molar mass | 457.838 g/mol |
| Appearance | White powder, hygroscopic |
| Density | 2.6–2.7 g/cm3 |
| Melting point | decomposes |
| negligible | |
| Solubility | soluble in acids |
| Pharmacology | |
| V03AE03 (WHO) | |
| Legal status |
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| Related compounds | |
Other anions | Lanthanum(III) oxide |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Lanthanum carbonate, La2(CO3)3, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal (bastnäsite), along with monazite.
Chemistry
[edit]Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example
- for production of lanthanum strontium manganite, primarily for solid oxide fuel cell applications;
- for production of certain high-temperature superconductors, such as La2-xSrxCuO2.
Medical uses
[edit]Lanthanum carbonate is used in medicine as a phosphate binder.[1] As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Due to its large size (1000 mg tablet is 2.2 cm in diameter), it may be possible to choke on the tablet if it is not chewed. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats with hyperphosphatemia it is available under the trade name Renalzin by Bayer Animal Health.[2]
However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.[3]
Other applications
[edit]Lanthanum carbonate is also used for the tinting of glass,[citation needed] for water treatment, and as a catalyst for hydrocarbon cracking.
References
[edit]- ^ Editorial Staff (December 2004). "Lanthanum Carbonate". All Micromedex Systems. Micromedex, Inc. Archived from the original on 2007-09-14. Retrieved 2007-11-25.
- ^ Bayer Animal Health (26 September 2008). "Bayer Animal Health launches Renalzin for Cats" (PDF). Archived from the original (PDF) on 7 July 2011. Retrieved 2008-09-30.
- ^ Tonelli, Marcello; Pannu, Neesh; Manns, Braden (2010). "Oral Phosphate Binders in Patients with Kidney Failure". New England Journal of Medicine. 362 (14): 1312–24. doi:10.1056/NEJMra0912522. PMID 20375408. S2CID 22322676.
External links
[edit]- Lanthanum - medlineplus.org
- Fosrenol.com - the manufacturer's web site
- Fosrenol - Drugs.com
- Fosrenol - Medscape.com
- PhosphorusControl.com - PhosphorusControl.com
- Bayer Animal Health