Protein-coding gene in the species Homo sapiens
GPI transamidase component PIG-T is an enzyme that in humans is encoded by the PIGT gene .[ 5] [ 6] [ 7]
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase . GPI transamidase mediates GPI anchoring in the endoplasmic reticulum , by catalyzing the transfer of fully assembled GPI units to proteins.[ 6]
PIGT has been shown to interact with PIGK [ 8] GPAA1 .[ 7] [ 9]
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