Tiodazosin

Tiodazosin
Names
	Preferred IUPAC name [4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][5-(methylsulfanyl)-1,3,4-oxadiazol-2-yl]methanone
Identifiers
CAS Number	66969-81-1 ;
3D model (JSmol)	Interactive image;
ChemSpider	54869;
PubChem CID	60891;
UNII	FQI0PYJ799 ;
CompTox Dashboard (EPA)	DTXSID90217180 ;
	InChI InChI=1S/C18H21N7O4S/c1-27-12-8-10-11(9-13(12)28-2)20-17(21-14(10)19)25-6-4-24(5-7-25)16(26)15-22-23-18(29-15)30-3/h8-9H,4-7H2,1-3H3,(H2,19,20,21) Key: MULPYFRDYRZMDS-UHFFFAOYSA-N;
	SMILES COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=NN=C(O4)SC)N)OC;
Properties
Chemical formula	C18H21N7O4S
Molar mass	431.47 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Tiodazosin is an α₁-adrenergic receptor antagonist.^[1]

References

^ Chiang, J; Hermodsson, G; Oie, S (1991). "The effect of alpha 1-acid glycoprotein on the pharmacological activity of alpha 1-adrenergic antagonists in rabbit aortic strips". The Journal of Pharmacy and Pharmacology. 43 (8): 540–7. doi:10.1111/j.2042-7158.1991.tb03533.x. PMID 1681068. S2CID 97860582.

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Names

Preferred IUPAC name [4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][5-(methylsulfanyl)-1,3,4-oxadiazol-2-yl]methanone
Identifiers
CAS Number	66969-81-1^Y
3D model (JSmol)	Interactive image
ChemSpider	54869
PubChem CID	60891
UNII	FQI0PYJ799^Y
CompTox Dashboard (EPA)	DTXSID90217180
InChI InChI=1S/C18H21N7O4S/c1-27-12-8-10-11(9-13(12)28-2)20-17(21-14(10)19)25-6-4-24(5-7-25)16(26)15-22-23-18(29-15)30-3/h8-9H,4-7H2,1-3H3,(H2,19,20,21) Key: MULPYFRDYRZMDS-UHFFFAOYSA-N
SMILES COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=NN=C(O4)SC)N)OC
Properties
Chemical formula	C₁₈H₂₁N₇O₄S
Molar mass	431.47 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references