BW284C51

BW284C51
Names
Preferred IUPAC name
4,4′-(3-Oxopentane-1,5-diyl)bis[N,N-dimethyl-N-(prop-2-en-1-yl)anilinium] dibromide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.129.545 Edit this at Wikidata
  • InChI=1S/C27H38N2O.2BrH/c1-7-21-28(3,4)25-15-9-23(10-16-25)13-19-27(30)20-14-24-11-17-26(18-12-24)29(5,6)22-8-2;;/h7-12,15-18H,1-2,13-14,19-22H2,3-6H3;2*1H/q+2;;/p-2
    Key: WKDURMTZOWGWTD-UHFFFAOYSA-L
  • C[N+](C)(CC=C)c1ccc(cc1)CCC(=O)CCc2ccc(cc2)[N+](C)(C)CC=C.[Br-].[Br-]
Properties
C27H38Br2N2O
Molar mass 566.422 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Toxic
GHS labelling:
GHS06: Toxic
Danger
H300, H310, H330
P260, P262, P264, P270, P271, P280, P284, P301+P310, P302+P350, P304+P340, P310, P320, P321, P322, P330, P361, P363, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

BW284C51 is a selective acetylcholinesterase inhibitor.[1] It is also a nicotinic antagonist.[2]

See also

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References

[edit]
  1. ^ FULTON, MP; MOGEY, GA (June 1954). "Some selective inhibitors of true cholinesterase". British Journal of Pharmacology and Chemotherapy. 9 (2): 138–44. doi:10.1111/j.1476-5381.1954.tb00832.x. PMC 1509427. PMID 13172421.
  2. ^ Olivera-Bravo, S; Ivorra, I; Morales, A (January 2005). "The acetylcholinesterase inhibitor BW284c51 is a potent blocker of Torpedo nicotinic AchRs incorporated into the Xenopus oocyte membrane". British Journal of Pharmacology. 144 (1): 88–97. doi:10.1038/sj.bjp.0705965. PMC 1575971. PMID 15644872.


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