Helicobacter bizzozeronii
| Helicobacter bizzozeronii | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Phylum: | Campylobacterota |
| Class: | "Campylobacteria" |
| Order: | Campylobacterales |
| Family: | Helicobacteraceae |
| Genus: | Helicobacter |
| Species: | H. bizzozeronii |
| Binomial name | |
| Helicobacter bizzozeronii Paster et al., 1991 | |
Helicobacter bizzozeronii is a species within the Helicobacter genus of Gram-negative bacteria.[1] Helicobacter pylori is by far the best known Helicobacter species, primarily because humans infected with it may develop gastrointestinal tract diseases such as stomach inflammation, stomach ulcers, duodenal ulcers, stomach cancers of the nonlymphoma type, and various subtypes of extranodal marginal zone lymphomass, e.g. those of the stomach, small intestines, large intestines, and rectumn. H. pylori is also associated with the development of bile duct cancer and has been associated with a wide range of other diseases although its role in the development of many of these other diseases requires further study.[2] Humans infected with H. bizzozeronii are prone to develop some of the same gastrointestinal diseases viz., stomach inflammation, stomach ulcers,[3] duodenal ulcers,[4] stomach cancers that are not lymphomas, and extranodal marginal B cell lymphomas of the stomach.[3] Other non-H. pylori Helicobacter species that are known to be associated with these gastrointestinal diseases are Helicobacter felis, Helicobacter salomonis, Helicobacter suis, and Helicobacter heilmannii s.s. Because of their disease associations, these four Helicobacter species plus H. bizzozeronii are often grouped together and termed Helicobacter heilmannii sensu lato.[citation needed]
Helicobacter bizzozeronii bacteria are detected in the stomachs of their natural hosts - cats, dogs, foxes, and lynxes, as well as in the saliva of dogs. Reports suggest that individuals, including children,[4] are infected with this bacterium by having close contact with these animals.[3] That is, H. bizzozeronii-associated diseases appear to be zoonotic diseases, i.e. infectious diseases that are caused by pathogen that spread from animals to humans.[3] It is important to diagnose H. bizzozeronii and the other H. heilmannii sensu lato infections in patients with the cited upper gastrointestinal tract diseases, including in particular extranodal marginal zone lymphoma of the stomach, because some of them have been successfully treated and cured using antibiotic-based drug regimens (e.g.amoxicillin, clarithromycin, plus a proton pump inhibitor[5] or metronidazole, clarithromycin, plus a proton pump inhibitor[3]) directed against the instigating bacterium.[3]
References
[edit]- ^ Péré-Védrenne C, Flahou B, Loke MF, Ménard A, Vadivelu J (September 2017). "Other Helicobacters, gastric and gut microbiota". Helicobacter. 22 (Suppl 1): e12407. doi:10.1111/hel.12407. PMID 28891140. S2CID 30040441.
- ^ Bravo D, Hoare A, Soto C, Valenzuela MA, Quest AF (July 2018). "Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects". World Journal of Gastroenterology. 24 (28): 3071–3089. doi:10.3748/wjg.v24.i28.3071. PMC 6064966. PMID 30065554.
- ^ a b c d e f Bento-Miranda M, Figueiredo C (December 2014). "Helicobacter heilmannii sensu lato: an overview of the infection in humans". World Journal of Gastroenterology. 20 (47): 17779–87. doi:10.3748/wjg.v20.i47.17779. PMC 4273128. PMID 25548476.
- ^ a b Iwanczak B, Biernat M, Iwanczak F, Grabinska J, Matusiewicz K, Gosciniak G (April 2012). "The clinical aspects of Helicobacter heilmannii infection in children with dyspeptic symptoms". Journal of Physiology and Pharmacology. 63 (2): 133–6. PMID 22653899.
- ^ Ménard A, Smet A (September 2019). "Review: Other Helicobacter species". Helicobacter. 24 (Suppl 1): e12645. doi:10.1111/hel.12645. PMID 31486233.