Fibrinolysis syndrome

Fibrinolysis syndrome
Fibrinolysis syndrome
Other names	Defibrinating syndrome

Fibrinolysis syndrome is characterized by an acute hemorrhagic state brought about by inability of the blood to clot, with massive hemorrhages into the skin producing blackish, purplish swellings and sloughing.^[1]^: 826

Symptoms

Hemorrhages (this includes severe bleeding of any particular area. Be it: nasal, rectal, oral, it also includes bleeding from scrapes, cuts, bruises (big bruises that do not disappear in the first two to three days).

Cause

The cause for Fibrinolysis syndrome, is the inability of the body to produce blood-coagulates to stop bleeding. What causes the body to not produce blood-coagulates are the low levels of fibrin, or therefore non-existent fibrin.^[2]

Diagnosis

Treatment

References

^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
^ Merskey, C.; Johnson, A. J.; Kleiner, G. J.; Wom, H. (1967). "The Defibrination Syndrome: Clinical Features and Laboratory Diagnosis". Department of Medicine and the American National Red Cross Research Laboratory. 13: 528. doi:10.1111/j.1365-2141.1967.tb00762.x. PMID 6029954. S2CID 20990370. Fibrin is a non-globular protein involved in the clotting of blood.

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[Andrews-1] James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.

[Merskey-2] Merskey, C.; Johnson, A. J.; Kleiner, G. J.; Wom, H. (1967). "The Defibrination Syndrome: Clinical Features and Laboratory Diagnosis". Department of Medicine and the American National Red Cross Research Laboratory. 13: 528. doi:10.1111/j.1365-2141.1967.tb00762.x. PMID 6029954. S2CID 20990370. Fibrin is a non-globular protein involved in the clotting of blood.

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v t e Cutaneous vasculitis and other vascular-related cutaneous conditions
Cutaneous vasculitis	Erythema elevatum diutinum Capillaritis Urticarial vasculitis Nodular vasculitis
Microvascular occlusion	Calciphylaxis Cryoglobulinemic purpura/Cryoglobulinemic vasculitis vascular coagulopathy: Livedoid vasculopathy Livedoid dermatitis Perinatal gangrene of the buttock Malignant atrophic papulosis Sneddon's syndrome
Purpura	Nonthrombocytopenic purpura: Cryofibrinogenemic purpura Drug-induced purpura Food-induced purpura IgA vasculitis Obstructive purpura Orthostatic purpura Purpura fulminans Purpura secondary to clotting disorders Purpuric agave dermatitis Pigmentary purpuric eruptions Solar purpura Traumatic purpura Waldenström hyperglobulinemic purpura Painful bruising syndrome ungrouped: Paroxysmal hand hematoma Postcardiotomy syndrome Deep vein thrombosis Superficial thrombophlebitis Mondor's disease Blueberry muffin baby Fibrinolysis syndrome
Systemic vasculitis	see Template:Systemic vasculitis
Vascular malformations	Arteriovenous malformation Bonnet–Dechaume–Blanc syndrome Cobb syndrome Parkes Weber syndrome Sinusoidal hemangioma lymphatic malformation Hennekam syndrome Aagenaes syndrome telangiectasia: Generalized essential telangiectasia Hereditary hemorrhagic telangiectasia Unilateral nevoid telangiectasia
Ulcer	Venous ulcer Arterial insufficiency ulcer Hematopoietic ulcer Neuropathic ulcer Acroangiodermatitis
Lymphedema	see Template:Lymphatic vessel disease
Ungrouped vascular-related cutaneous conditions	Raynaud's phenomenon Thromboangiitis obliterans Erythromelalgia Septic thrombophlebitis Arteriosclerosis obliterans Bier spots/Marshall–White syndrome Cholesterol embolus Reactive angioendotheliomatosis Trousseau's syndrome