Protein-coding gene in the species Homo sapiens
Polyadenylate-binding protein 3 is a protein that in humans is encoded by the PABPC3 gene .[ 3] [ 4] [ 5] PABPC3 is a member of a larger family of poly(A)-binding proteins in the human genome.
Marques AC, Dupanloup I, Vinckenbosch N, et al. (2006). "Emergence of young human genes after a burst of retroposition in primates" . PLOS Biol . 3 (11): e357. doi :10.1371/journal.pbio.0030357 . PMC 1251493 . PMID 16201836 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 . Féral C, Guellaën G, Pawlak A (2002). "Human testis expresses a specific poly(A)-binding protein" . Nucleic Acids Res . 29 (9): 1872–83. doi :10.1093/nar/29.9.1872 . PMC 37253 . PMID 11328870 . Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 . PMID 11230166 . Hoshino S, Imai M, Kobayashi T, et al. (1999). "The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein" . J. Biol. Chem . 274 (24): 16677–80. doi :10.1074/jbc.274.24.16677 . PMID 10358005 . PDBe-KB provides an overview of all the structure information available in the PDB for Human Polyadenylate-binding protein 3 (PABPC3)
PDB gallery
1g9l : SOLUTION STRUCTURE OF THE PABC DOMAIN OF HUMAN POLY(A) BINDING PROTEIN
1jgn : Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2
1jh4 : Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip1
2d9p : Solution structure of RNA binding domain 4 in Polyadenylation binding protein 3