Pukateine
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| Other names | (R)-11-hydroxy-1,2-methylenedioxyaporphine |
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| Formula | C18H17NO3 |
| Molar mass | 295.338 g·mol−1 |
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Pukateine is an alkaloid found in the bark of the New Zealand tree Laurelia novae-zelandiae ("Pukatea"), as well as some South American plants.[1] An extract from pukatea is used in traditional Māori herbal medicine as an analgesic.[2][3]
Bernard Cracroft Aston studied the physical and chemical characteristics of the compound, and presented a paper with his findings to the Royal Society of New Zealand on 11 May 1909.[4]
See also
[edit]References
[edit]- ^ Quiroz-Carreño S, Pastene-Navarrete E, Espinoza-Pinochet C, Muñoz-Núñez E, Devotto-Moreno L, Céspedes-Acuña CL, Alarcón-Enos J (November 2020). "Assessment of Insecticidal Activity of Benzylisoquinoline Alkaloids from Chilean Rhamnaceae Plants against Fruit-Fly Drosophila melanogaster and the Lepidopteran Crop Pest Cydia pomonella". Molecules. 25 (21). Basel, Switzerland: 5094. doi:10.3390/molecules25215094. PMC 7663414. PMID 33153001.
- ^ Dajas-Bailador FA, Asencio M, Bonilla C, Scorza MC, Echeverry C, Reyes-Parada M, Silveira R, Protais P, Russell G, Cassels BK, Dajas F (March 1999). "Dopaminergic pharmacology and antioxidant properties of pukateine, a natural product lead for the design of agents increasing dopamine neurotransmission". General Pharmacology. 32 (3): 373–9. doi:10.1016/s0306-3623(98)00210-9. PMID 10211594.
- ^ Valiente M, D'Ocon P, Noguera MA, Cassels BK, Lugnier C, Ivorra MD (July 2004). "Vascular activity of (-)-anonaine, (-)-roemerine and (-)-pukateine, three natural 6a(R)-1,2-methylenedioxyaporphines with different affinities for alpha1-adrenoceptor subtypes". Planta Medica. 70 (7): 603–9. doi:10.1055/s-2004-827181. PMID 15254852. S2CID 260249660.
- ^ Aston BC (1909). "The Alkaloids of the Pukatea". Transactions of the Royal Society of New Zealand. 42. Retrieved October 20, 2015.
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