List of highways numbered 281
The following highways are numbered 281:
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Canada
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Japan
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United States
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U.S. Route 281
Alabama State Route 281
Arkansas Highway 281
California State Route 281
Florida State Road 281
Georgia State Route 281
Iowa Highway 281
Kentucky Route 281
Maryland Route 281
Minnesota State Highway 281 (former)
Montana Secondary Highway 281 (former)
New Mexico State Route 281
New York State Route 281
North Carolina Highway 281
North Dakota Highway 281
Ohio State Route 281
Oklahoma State Highway 281A
Oregon Route 281
Pennsylvania Route 281
South Carolina Highway 281
Tennessee State Route 281
Texas State Highway 281 (former proposed) 
Utah State Route 281 (former)
Washington State Route 281
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| Preceded by 280 | Lists of highways 281 | Succeeded by 282 |
This article includes a list of roads, streets, highways, or other routes that are associated with the same title.
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