Protein-coding gene in the species Homo sapiens
Serine/threonine-protein kinase SIK2 is an enzyme that in humans is encoded by the SIK2 gene .[ 5] [ 6]
SNF1LK2 has been shown to interact with CRTC2 .[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000170145 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037112 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Katoh M, Katoh M (May 2004). "Identification and characterization of human FOXN5 and rat Foxn5 genes in silico". International Journal of Oncology . 24 (5): 1339–44. doi :10.3892/ijo.24.5.1339 . PMID 15067358 . ^ "Entrez Gene: SNF1LK2 SNF1-like kinase 2" .^ Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR, Takemori H, Okamoto M, Montminy M (Oct 2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector" . Cell . 119 (1): 61–74. doi :10.1016/j.cell.2004.09.015 PMID 15454081 . S2CID 18616459 . Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (Jun 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research . 9 (3): 99–106. CiteSeerX 10.1.1.500.923 doi :10.1093/dnares/9.3.99 . PMID 12168954 . Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Research . 6 (9): 791–806. doi :10.1101/gr.6.9.791 PMID 8889548 . Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Research . 5 (5): 277–86. doi :10.1093/dnares/5.5.277 PMID 9872452 . Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs" . Genome Research . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . Horike N, Takemori H, Katoh Y, Doi J, Min L, Asano T, Sun XJ, Yamamoto H, Kasayama S, Muraoka M, Nonaka Y, Okamoto M (May 2003). "Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2" . The Journal of Biological Chemistry . 278 (20): 18440–7. doi :10.1074/jbc.M211770200 PMID 12624099 . Katoh M, Katoh M (Nov 2003). "Identification and characterization of human KIAA1391 and mouse Kiaa1391 genes encoding novel RhoGAP family proteins with RA domain and ANXL repeats". International Journal of Oncology . 23 (5): 1471–6. doi :10.3892/ijo.23.5.1471 . PMID 14532992 . Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR (Feb 2004). "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1" . The EMBO Journal . 23 (4): 833–43. doi :10.1038/sj.emboj.7600110 . PMC 381014 PMID 14976552 . Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR, Takemori H, Okamoto M, Montminy M (Oct 2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector" . Cell . 119 (1): 61–74. doi :10.1016/j.cell.2004.09.015 PMID 15454081 . S2CID 18616459 . Katoh Y, Takemori H, Min L, Muraoka M, Doi J, Horike N, Okamoto M (Nov 2004). "Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm" . European Journal of Biochemistry . 271 (21): 4307–19. doi :10.1111/j.1432-1033.2004.04372.x PMID 15511237 .
Activity Regulation Classification Kinetics Types
