Anant Parekh

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The Honourable
Anant Parekh
FRS FMedSci MAE
Born
Anant B. Parekh

Kingston upon Hull[2]
EducationHymers College[2]
Alma materUniversity of Oxford (BA, DPhil)
Scientific career
FieldsPhysiology
InstitutionsMax Planck Institute for Biophysical Chemistry
University of Oxford
ThesisStimulus-contraction coupling in circular smooth muscle of guinea-pig stomach (1991)
Doctoral advisorAlison Brading[1]
Websitewww.dpag.ox.ac.uk/team/anant-parekh

Anant B. Parekh FRS FMedSci MAE is professor of Physiology at the University of Oxford[3][4][5] and a Fellow of Merton College, Oxford.[6][7][8]

Education[edit]

Parekh was a student at Hymers College and University College, Oxford. He was awarded a Doctor of Philosophy degree by the University of Oxford in 1991 for research on smooth muscle supervised by Alison Brading.[1] He carried out postdoctoral research at the Max Planck Institute for biophysical Chemistry (Goettingen) in the laboratory of Nobel Laureate Erwin Neher, working with Walter Stuehmer and then Reinhold Penner.

Career and research[edit]

Parekh's research investigates the physiology of Calcium signalling and Calcium release activated channels (CRACs).[3][4][5][7][8] He investigates how cells communicate with one another, with an emphasis on how the ubiquitous intracellular signalling messenger calcium controls biological functions such as secretion, energy production and gene expression.[9][8][10][11][12]

Parekh's research investigates how aberrant calcium signals can contribute to ill health in humans, including allergies and asthma.[9] Using various cell model systems and human tissue, he studies the physiology, cell biology and biochemistry of store-operated calcium channel proteins.[9] Opening of these channels leads to calcium entry into the cell from the blood, triggering important physiological responses.[9] Too much or too little calcium entry can lead to disease and tissue damage which makes the Calcium release activated channels (CRAC) promising biological targets for drug discovery.[9]

Awards and honours[edit]

Parekh was elected a Fellow of the Royal Society (FRS) in 2019.[9] He was also elected member of Academia Europaea (MAE) in 2002 and a Fellow of the Academy of Medical Sciences (FMedSci) in 2012.[9][13] He was awarded the George Lindor Brown prize lecture by The Physiological Society in 2012.[9]

Personal life[edit]

Parekh is the youngest of three sons of Labour peer Bhikhu Parekh, Lord Parekh,[14] all of whom gained scholarships to study at the University of Oxford.[2]

References[edit]

  1. ^ a b Parekh, Anant B. (1991). Stimulus-contraction coupling in circular smooth muscle of guinea-pig stomach (DPhil thesis). University of Oxford. OCLC 59947010. EThOS uk.bl.ethos.292570.
  2. ^ a b c Stephenson, Barnabas (25 September 2019). "Man becomes first from Hull to be inducted into prestigious group". Hull Daily Mail. Archived from the original on 1 November 2019.
  3. ^ a b Anant Parekh publications from Europe PubMed Central
  4. ^ a b Anant Parekh publications indexed by the Scopus bibliographic database. (subscription required)
  5. ^ a b "Anant Parekh – Physiology, Anatomy and Genetics". Oxford: University of Oxford.
  6. ^ "Professor Anant Parekh". Oxford: University of Oxford.
  7. ^ a b Anant Parekh's ORCID 0000-0002-4860-1644
  8. ^ a b c Parekh, Anant B.; Putney, James W. (2005). "Store-Operated Calcium Channels". Physiological Reviews. 85 (2): 757–810. doi:10.1152/physrev.00057.2003. ISSN 0031-9333. PMID 15788710.
  9. ^ a b c d e f g h Anon (2019). "Professor Anant Parekh FRS". royalsociety.org. London: Royal Society. Archived from the original on 24 April 2019. Material was copied from this source, which is available under a Creative Commons Attribution 4.0 International License.
  10. ^ Parekh, A. B.; Penner, R. (1997). "Store depletion and calcium influx". Physiological Reviews. 77 (4): 901–930. doi:10.1152/physrev.1997.77.4.901. ISSN 0031-9333. PMID 9354808.
  11. ^ Parekh, Anant B.; Terlau, Heinrich; Stühmer, Walter (1993). "Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger". Nature. 364 (6440): 814–818. Bibcode:1993Natur.364..814P. doi:10.1038/364814a0. ISSN 0028-0836. PMID 8395025. S2CID 4339790.
  12. ^ Parekh, Anant B. (2016). "Advances in intracellular Ca2+signalling". The Journal of Physiology. 594 (11): 2811–2812. doi:10.1113/JP272230. ISSN 0022-3751. PMC 4887675. PMID 27246547.
  13. ^ Anon (2012). "Professor Anant Parekh". acmedsci.ac.uk. London: Academy of Medical Sciences.
  14. ^ Anon (2003). "Parekh". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.U30023. (Subscription or UK public library membership required.)
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