Protein-coding gene in the species Homo sapiens
Dihydropyrimidinase-related protein 5 is an enzyme that in humans is encoded by the DPYSL5 gene .[ 5] [ 6] [ 7]
Members of the CRMP family, such as DPYSL5, are believed to play a role in growth cone guidance during neural development.[supplied by OMIM][ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000157851 – Ensembl , May 2017 ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029168 – Ensembl , May 2017 ^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ Inatome R, Tsujimura T, Hitomi T, Mitsui N, Hermann P, Kuroda S, Yamamura H, Yanagi S (Oct 2000). "Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain" . J Biol Chem . 275 (35): 27291–302. doi :10.1074/jbc.M910126199 . PMID 10851247 . ^ Horiuchi M, El Far O, Betz H (Nov 2000). "Ulip6, a novel unc-33 and dihydropyrimidinase related protein highly expressed in developing rat brain" . FEBS Lett . 480 (2–3): 283–6. doi :10.1016/S0014-5793(00)01952-9 . PMID 11034345 . S2CID 42248702 . ^ a b "Entrez Gene: DPYSL5 dihydropyrimidinase-like 5" . Cross SA, Salomao DR, Parisi JE, et al. (2003). "Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG". Ann. Neurol . 54 (1): 38–50. doi :10.1002/ana.10587 . PMID 12838519 . S2CID 36493404 . Fukada M, Watakabe I, Yuasa-Kawada J, et al. (2001). "Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family" . J. Biol. Chem . 275 (48): 37957–65. doi :10.1074/jbc.M003277200 . PMID 10956643 . Yu Z, Kryzer TJ, Griesmann GE, et al. (2001). "CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity". Ann. Neurol . 49 (2): 146–54. doi :10.1002/1531-8249(20010201)49:2<146::AID-ANA34>3.0.CO;2-E . PMID 11220734 . S2CID 3239861 . Ricard D, Rogemond V, Charrier E, et al. (2001). "Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes" . J. Neurosci . 21 (18): 7203–14. doi :10.1523/JNEUROSCI.21-18-07203.2001 . PMC 6763003 . PMID 11549731 . Mitsui N, Inatome R, Takahashi S, et al. (2002). "Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling" . EMBO J . 21 (13): 3274–85. doi :10.1093/emboj/cdf328 . PMC 125392 . PMID 12093729 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Overview of all the structural information available in the PDB for UniProt : Q9BPU6 (Dihydropyrimidinase-related protein 5) at the PDBe-KB .