EIF3CL

EIF3CL
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3J8B, 3J8C
Identifiers
Aliases	EIF3CL, eukaryotic translation initiation factor 3 subunit C like
External IDs	GeneCards: EIF3CL
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p12.1 Start 28,379,579 bp[1] End 28,403,841 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left ventricle skeletal muscle tissue gastrocnemius muscle hippocampus proper putamen dorsolateral prefrontal cortex amygdala stromal cell of endometrium Brodmann area 9 nucleus accumbens n/a More reference expression data BioGPS n/a
Gene ontology Molecular function translation initiation factor binding translation initiation factor activity RNA binding Cellular component cytoplasm eukaryotic translation initiation factor 3 complex eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex Biological process translational initiation protein biosynthesis formation of cytoplasmic translation initiation complex cytoplasmic translational initiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 728689 n/a Ensembl ENSG00000205609 n/a UniProt B5ME19 n/a RefSeq (mRNA) NM_001099661 NM_001317856 NM_001317857 n/a RefSeq (protein) NP_001093131 NP_001304785 NP_001304786 n/a Location (UCSC) Chr 16: 28.38 – 28.4 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Eukaryotic translation initiation factor 3 subunit C like is a protein that in humans is encoded by the EIF3CL gene. ^[3]

Function[edit]

The protein encoded by this gene is a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. The encoded protein is nearly identical to another protein, eIF3c, from a related gene. The eIF3 complex binds the 40S ribosome and mRNAs to enable translation initiation. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015].

See also[edit]

• Eukaryotic initiation factor 3 (eIF3)

References[edit]

Further reading[edit]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.