Laboratory for Bioregenerative Medicine and Surgery
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The Laboratory for Bioregenerative Medicine and Surgery (LBMS) is a leading regenerative medicine research laboratory within the Department of Surgery at Weill Cornell Medical College in New York City. Under the leadership of its founder and director, Jason Spector, MD FACS, the LBMS has since its inception in 2006 focused its time and resources on the study of issues most directly relevant to reconstructive surgery. These involve pharmacologic means to reduce reperfusion injury,[1] the use of therapeutic ultrasound for noninvasive venous ablation,[2] and most notably, a novel approach for the creation of artificial tissues.[3]
This approach involves the fabrication of a three-dimensional construct that contains within it sacrificial microfibers that are in direct continuity with inflow and outflow macrochannels. Subsequent dissolution of the sacrificial fibers results in a construct that contains a microchannel network that closely approximates that which is found capillary beds. Most importantly, the inflow and outflow macrochannels are of sufficient size to be amenable to microsurgical manipulation, and therefore the construct is of clinical significance.[citation needed] This work has been reported on by the Associated Press,[4] National Public Radio,[5] the Discovery Channel,[6] and Planet Green.[7]
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References[edit]
- ^ Henderson, Peter W.; Singh, Sunil P.; Belkin, Daniel; Nagineni, Vamsi; Weinstein, Andrew L.; Weissich, Jacob; Spector, Jason A. (2010). "Hydrogen Sulfide Protects Against Ischemia-Reperfusion Injury in an in Vitro Model of Cutaneous Tissue Transplantation1". Journal of Surgical Research. 159 (1): 451–5. doi:10.1016/j.jss.2009.05.010. PMID 19811790.
- ^ Henderson, Peter W.; Lewis, George K.; Shaikh, Naima; Sohn, Allie; Weinstein, Andrew L.; Olbricht, William L.; Spector, Jason A. (2010). "A portable high-intensity focused ultrasound device for noninvasive venous ablation". Journal of Vascular Surgery. 51 (3): 707–11. doi:10.1016/j.jvs.2009.10.049. PMID 20045610.
- ^ Bellan, Leon M.; Singh, Sunil P.; Henderson, Peter W.; Porri, Teresa J.; Craighead, Harold G.; Spector, Jason A. (2009). "Fabrication of an artificial 3-dimensional vascular network using sacrificial sugar structures". Soft Matter. 5 (7): 1354–7. doi:10.1039/B819905A.
- ^ "Sweet! Cotton candy may help labs grow tissue". USA Today. February 11, 2009.
- ^ "Cotton Candy, A Medical Wonder?". NPR.
- ^ "Daily Planet". Discovery Channel. February 2009. Archived from the original on 2012-02-15. Retrieved 2010-06-08.
- ^ "Dean of Invention". Planet Green.