Lithium lactate
From Wikipedia the free encyclopedia
Names | |
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Other names Lithium 2-hydroxypropanoate | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
ECHA InfoCard | 100.011.602 |
EC Number |
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PubChem CID | |
CompTox Dashboard (EPA) | |
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Properties | |
C 3H 5LiO 3[1][2] | |
Molar mass | 96.01 |
Appearance | Amorphous solid |
Density | g/cm3 |
Melting point | 300 °C (572 °F; 573 K) |
Very soluble | |
Hazards | |
GHS labelling:[3] | |
Warning | |
H315, H319, H335 | |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 | |
Related compounds | |
Other cations | Sodium lactate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Lithium lactate is a chemical compound, a salt of lithium and lactic acid with the formula CH3CH(OH)COOLi,[4] an amorphous solid, very soluble in water.[5]
Synthesis
[edit]Synthesis is by neutralization of lactic acid with lithium hydroxide:
- LiOH + CH3CH(OH)COOH → CH3CH(OH)COOLi + H2O
Physical properties
[edit]Lithium lactate forms an amorphous solid.
It dissolves very well in water[6] and organic solvents.
The compound demonstrates optical isomerism.
Lithium lactate emits acrid smoke when heated to decomposition.[7]
Chemical properties
[edit]Lithium lactate reacts with triphosgene to obtain lactic acid-O-internal anhydride.[8] It can be used as a precursor to prepare Li4SiO4,[9] Li4Ti5O12/C[10] and other materials.
Use
[edit]Lithium lactate is part of drugs that promote the excretion of uric acid from the body.[11]
It is also used as an Antipsychotic.[12]
References
[edit]- ^ "867-55-0 CAS | LITHIUM LACTATE | Laboratory Chemicals | Article No. 04444". Loba Chemie. Retrieved 17 January 2022.
- ^ "27848-80-2 - L-(+)-Lactic acid lithium salt, Thermo Scientific - Lithium Lactate - J18160 - Alfa Aesar". Alfa Aesar. Retrieved 17 January 2022.
- ^ "Lithium lactate". pubchem.ncbi.nlm.nih.gov. Retrieved 22 January 2022.
- ^ "Lithium Lactate". American Elements. Retrieved 17 January 2022.
- ^ "Lithium lactate". Sigma Aldrich. Retrieved 17 January 2022.
- ^ Lewis, Robert A. (31 May 2016). Hawley's Condensed Chemical Dictionary. John Wiley & Sons. p. 840. ISBN 978-1-118-13515-0. Retrieved 17 January 2022.
- ^ Lewis, Richard J. (13 June 2008). Hazardous Chemicals Desk Reference. John Wiley & Sons. p. 844. ISBN 978-0-470-18024-2. Retrieved 17 January 2022.
- ^ Nölle, Roman; Schmiegel, Jan-Patrick; Winter, Martin; Placke, Tobias (14 January 2020). "Tailoring Electrolyte Additives with Synergistic Functional Moieties for Silicon Negative Electrode-Based Lithium Ion Batteries: A Case Study on Lactic Acid O-Carboxyanhydride". Chemistry of Materials. 32 (1): 173–185. doi:10.1021/acs.chemmater.9b03173. ISSN 0897-4756. S2CID 213665815. Retrieved 23 January 2022.
- ^ Yang, Xinwei; Liu, Wenqiang; Sun, Jian; Hu, Yingchao; Wang, Wenyu; Chen, Hongqiang; Zhang, Yang; Li, Xian; Xu, Minghou (2016). "Preparation of Novel Li4SiO4 Sorbents with Superior Performance at Low CO2 Concentration". ChemSusChem. 9 (13): 1607–1613. doi:10.1002/cssc.201501699. ISSN 1864-564X. PMID 27312486. Retrieved 23 January 2022.
- ^ Stenina, I. A.; Sobolev, A. N.; Kuz’mina, A. A.; Kulova, T. L.; Yaroslavtsev, A. B. (1 August 2019). "Effect of the Carbon Source on the Electrochemical Properties of Li4Ti5O12/C Composites Prepared by Solid-State Synthesis". Inorganic Materials. 55 (8): 803–809. doi:10.1134/S0020168519080156. ISSN 1608-3172. S2CID 201715779. Retrieved 23 January 2022.
- ^ Handler, J. S. (October 1, 1960). "The role of lactic acid in the reduced excretion of uric acid in toxemia of pregnancy". The Journal of Clinical Investigation. 39 (10): 1526–1532. doi:10.1172/JCI104172. ISSN 0021-9738. PMC 441887. PMID 13711188.
- ^ Wang, Quan; Xu, Xinxiu; Li, Jun; Liu, Jing; Gu, Haifeng; Zhang, Ru; Chen, Jiekai; Kuang, Yin; Fei, Jian; Jiang, Cong; Wang, Ping; Pei, Duanqing; Ding, Sheng; Xie, Xin (July 5, 2011). "Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells". Cell Research. 21 (10): 1424–1435. doi:10.1038/cr.2011.108. ISSN 1748-7838. PMC 3193456. PMID 21727907.