MTSA From Wikipedia the free encyclopedia The initials MTSA could stand for: Metropolitan Travel Survey Archive Mobile Telecommunications Sourcing Act Maritime Transportation Security Act of 2002 Methylated-thiol-coenzyme M methyltransferase, an enzyme Topics referred to by the same term This disambiguation page lists articles associated with the title MTSA.If an internal link led you here, you may wish to change the link to point directly to the intended article.