Methyl caffeate
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Chemical structure of methyl caffeate | |
Names | |
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Preferred IUPAC name Methyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate | |
Other names | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
ECHA InfoCard | 100.236.052 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C10H10O4 | |
Molar mass | 194.186 g·mol−1 |
Related compounds | |
Related compounds | Caffeic acid, Ethyl caffeate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Methyl caffeate is an ester of caffeic acid, a naturally occurring phenolic compound. It is an α-glucosidase inhibitor.[1] Its physical form is a powder.
Natural occurrences
[edit]Methyl caffeate can be found in the fruit of Solanum torvum.[2]
Health effect
[edit]Methyl caffeate shows an antidiabetic effect in streptozotocin-induced diabetic rats.[2]
References
[edit]- ^ Takahashi, Keisuke; Yoshioka, Yasuyuki; Kato, Eisuke; Katsuki, Shigeki; Iida, Osamu; Hosokawa, Keizo; Kawabata, Jun (2014). "Methyl Caffeate as an α-Glucosidase Inhibitor from Solanum torvum Fruits and the Activity of Related Compounds". Bioscience, Biotechnology, and Biochemistry. 74 (4): 741–745. doi:10.1271/bbb.90789. hdl:2115/53430. PMID 20378981. S2CID 23067847.
- ^ a b Gandhi, Gopalsamy Rajiv; Ignacimuthu, Savarimuthu; Paulraj, Michael Gabriel; Sasikumar, Ponnusamy (2011). "Antihyperglycemic activity and antidiabetic effect of methyl caffeate isolated from Solanum torvum Swartz. Fruit in streptozotocin induced diabetic rats". European Journal of Pharmacology. 670 (2–3): 623–631. doi:10.1016/j.ejphar.2011.09.159. PMID 21963451.