Monobenzyl phthalate
From Wikipedia the free encyclopedia
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| Names | |
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| Preferred IUPAC name 2-[(Benzyloxy)carbonyl]benzoic acid | |
| Other names | |
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3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.017.974 |
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PubChem CID | |
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CompTox Dashboard (EPA) | |
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| Properties | |
| C15H12O4 | |
| Molar mass | 256.257 g·mol−1 |
| Hazards | |
| GHS labelling: | |
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| Warning | |
| H319 | |
| P264, P280, P305+P351+P338, P337+P313 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Monobenzyl phthalate (MBzP) also known as 1,2-Benzenedicarboxylic acid, 1-(phenylmethyl) ester is an organic compound with the condensed structural formula C6H5CH2OOCC6H4COOH. It is the major metabolite of butyl benzyl phthalate(BBP), a common plasticizer.[2] BBP can also be metabolized into monobutyl phthalate (MBP).[3][4] Like many phthalates, BBP has attracted attention as a potential endocrine disruptor.[5][6][7]
References[edit]
- ^ a b c d e "Monobenzyl phthalate". PubChem. National Center for Biotechnology Information, U.S. National Library of Medicine. February 29, 2020. Retrieved March 5, 2020.
- ^ Chatterjee, Subhankar; Karlovsky, Petr (June 2010). "Removal of the endocrine disrupter butyl benzyl phthalate from the environment". Applied Microbiology and Biotechnology. 87 (1): 61–73. doi:10.1007/s00253-010-2570-y. PMC 2872021. PMID 20396882.
- ^ Huang, Jingyu; Nkrumah, Philip N.; Li, Yi; Appiah-Sefah, Gloria (2013). "Chemical Behavior of Phthalates Under Abiotic Conditions in Landfills". Reviews of Environmental Contamination and Toxicology. Vol. 224. New York, NY: Springer Science+Business Media. pp. 39–52. doi:10.1007/978-1-4614-5882-1_2. ISBN 9781461458814. PMID 23232918.
- ^ Saillenfait AM, Sabaté JP, Gallissot F (2002). "Comparative embryotoxicities of butyl benzyl phthalate, mono-n-butyl phthalate and mono-benzyl phthalate in mice and rats: in vivo and in vitro observations". Reproductive Toxicology. 17 (5): 575–83. doi:10.1016/s0890-6238(03)00102-3. PMID 14555196.
- ^ Du, Zuo; Cao, Yun-Feng; Li, Sai-Nan; Hu, Cui-Min; Fu, Zhi-Wei; Huang, Chun-Ting; Sun, Xiao-Yu; Liu, Yong-Zhe; Yang, Kun; Fang, Zhong-Ze (April 2018). "Inhibition of UDP-glucuronosyltransferases (UGTs) by phthalate monoesters". Chemosphere. 197: 7–13. Bibcode:2018Chmsp.197....7D. doi:10.1016/j.chemosphere.2018.01.010. PMID 29328989.
- ^ Ema M, Harazono A, Miyawaki E, Ogawa Y (July 1996). "Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the plasticizer n-butyl benzyl phthalate, in rats". Toxicology Letters. 86 (1): 19–25. doi:10.1016/0378-4274(96)03665-x. PMID 8685916.
- ^ Ema M, Harazono A, Miyawaki E, Ogawa Y (1995). "Characterization of developmental toxicity of mono-n-benzyl phthalate in rats". Reproductive Toxicology. 10 (5): 365–72. doi:10.1016/0890-6238(96)00082-2. PMID 8888408.