Ravi Salgia
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Ravi Salgia | |
|---|---|
| Born | 1960 (age 63–64) |
| Citizenship | American |
| Alma mater | Loyola University of Chicago |
| Spouse | Deborah Ann Salgia |
| Children | 3 |
| Scientific career | |
| Fields | Oncology |
| Institutions | |
Ravi Salgia (born 1960) is a translational thoracic oncologist, clinician/scientist, and academician.[1]
Biography and career
[edit]Salgia is the Arthur & Rosalie Kaplan Endowed Chair of Medical Oncology at City of Hope National Medical Center in Duarte, California. He also serves as Associate Director for Clinical Sciences at City of Hope National Medical Center. Prior to joining City of Hope, he served as tenured Professor of Medicine, Pathology and Dermatology, Director of the Thoracic Oncology Program and the Aerodigestive Tract Program Translational Research Lab in the section of Hematology/Oncology, Vice Chair for Translational Research in the Department of Medicine and Associate Director for Translational Science at the University of Chicago Comprehensive Cancer Center in Chicago.[2]
During his fellowship in Professor James Griffin's laboratory at Harvard, Salgia worked on the cytoskeleton, signal transduction pathways and hematpoiesis/Chronic myelogenous leukemia.[3][4][5][6] He was the first to fully clone the focal adhesion protein paxillin (human and chicken) and demonstrate its role in oncogenic transformation.[7] As an independent clinician-scientist, Salgia's major research interests include elucidating how the receptor tyrosine kinases affect cell growth, and understanding tumor heterogeneity, including the role of cell-signaling pathways, mitochondria, immunology, and mathematical modeling[8]
Salgia was born in Indore, Madhya Pradesh, India. He earned his undergraduate degree summa cum laude in mathematics, biology, and chemistry, minor in physics and then his medical degree and Ph.D. in biochemistry and biophysics from Loyola University of Chicago.[9] There he also completed a fellowship in neurochemistry and physiology. He continued his postgraduate training with an internship and residency in internal medicine at the Johns Hopkins Hospital in Baltimore, followed by a fellowship in medical oncology at Dana–Farber Cancer Institute in Boston, during which time he also served as a clinical fellow at Harvard Medical School in Boston.[10]
Salgia has been married to Deborah A. Salgia since 1990 and they have three children.[citation needed]
References
[edit]- ^ "Ravi Salgia, MD, PhD, Joins City of Hope". ascopost.com. Retrieved 8 September 2019.
- ^ "Acclaimed oncologist/researcher Ravi Salgia joins City of Hope as chair of medical oncology". www.cityofhope.org. Retrieved 9 September 2019.
- ^ Salgia, R.; Avraham, S.; Pisick, E.; Li, J. L.; Raja, S.; Greenfield, E. A.; Sattler, M.; Avraham, H.; Griffin, J. D. (6 December 1996). "The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells". The Journal of Biological Chemistry. 271 (49): 31222–31226. doi:10.1074/jbc.271.49.31222. ISSN 0021-9258. PMID 8940124.
- ^ Salgia, R.; Pisick, E.; Sattler, M.; Li, J. L.; Uemura, N.; Wong, W. K.; Burky, S. A.; Hirai, H.; Chen, L. B. (11 October 1996). "p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene". The Journal of Biological Chemistry. 271 (41): 25198–25203. doi:10.1074/jbc.271.41.25198. ISSN 0021-9258. PMID 8810278.
- ^ Salgia, R.; Sattler, M.; Pisick, E.; Li, J. L.; Griffin, J. D. (February 1996). "p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl". Experimental Hematology. 24 (2): 310–313. ISSN 0301-472X. PMID 8641358.
- ^ Okuda, K.; Matulonis, U.; Salgia, R.; Kanakura, Y.; Druker, B.; Griffin, J. D. (October 1994). "Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1". Experimental Hematology. 22 (11): 1111–1117. ISSN 0301-472X. PMID 7925778.
- ^ Salgia, R.; Li, J. L.; Lo, S. H.; Brunkhorst, B.; Kansas, G. S.; Sobhany, E. S.; Sun, Y.; Pisick, E.; Hallek, M. (10 March 1995). "Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL". The Journal of Biological Chemistry. 270 (10): 5039–5047. doi:10.1074/jbc.270.10.5039. ISSN 0021-9258. PMID 7534286.
- ^ pubmeddev. "ravi Salgia - PubMed - NCBI". www.ncbi.nlm.nih.gov. Retrieved 9 September 2019.
- ^ "Ravi Salgia, M.D., Ph.D., Chair and Professor of City of Hope's Department of Medical Oncology & Therapeutics Research". www.cityofhope.org. Retrieved 9 September 2019.
- ^ "Acclaimed Oncologist/Researcher Ravi Salgia Joins City of Hope as Chair of Medical Oncology". www.businesswire.com. 13 January 2016. Retrieved 9 September 2019.