Spybot From Wikipedia the free encyclopedia Look up spy or bot in Wiktionary, the free dictionary. Spybot may refer to: Spybot – Search & Destroy, a spyware and adware removal computer program Spybot worm, a family of computer worms Topics referred to by the same term This disambiguation page lists articles associated with the title Spybot.If an internal link led you here, you may wish to change the link to point directly to the intended article.