Thiobutabarbital
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-Thiobutabarbital_Structural_Formula_V1.svg) | |
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| Other names | Thiobutabarbital, Inactin, Brevinarcon, 5-sec-Butyl-5-ethyl-2-thiobarbituric acid |
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| ECHA InfoCard | 100.016.600 |
| Chemical and physical data | |
| Formula | C10H16N2O2S |
| Molar mass | 228.31 g·mol−1 |
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Thiobutabarbital (Inactin, Brevinarcon) is a short-acting barbiturate derivative invented in the 1950s. It has sedative, anticonvulsant and hypnotic effects, and is still used in veterinary medicine for induction in surgical anaesthesia.[1]
Stereochemistry
[edit]Thiobutabarbital contains a stereocenter and consists of two enantiomers. This is a racemate, i.e. a 1: 1 mixture of ( R ) - and the ( S ) - form:[2]
| Enantiomers of Thiobutabarbital | |
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-Thiobutabarbital_Structural_Formula_V1.svg) (R)-Form | -Thiobutabarbital_Structural_Formula_V1.svg) (S)-Form |
References
[edit]- ^ Rieg T, Richter K, Osswald H, Vallon V (October 2004). "Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia". Naunyn-Schmiedeberg's Archives of Pharmacology. 370 (4): 320–3. doi:10.1007/s00210-004-0982-x. PMID 15549274. S2CID 25580831.
- ^ Entry on Thiobutabarbital. at: Römpp Online. Georg Thieme Verlag, retrieved 15. Juni 2014.
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